Lucie Berkovitch

Lucie Berkovitch

@lucieberko.bsky.social

MD. PhD. Psychiatrist and researcher at GHU Paris psychiatrie & neurosciences - Psychedelics, consciousness and psychiatry https://lucie-berkovitch.fr https://scholar.google.com/citations?user=7ShQ

700 Followers 427 Following 52 Posts Joined Nov 2024
1 month ago
Lucie Berkovitch Site personnel de Lucie Berkovitch, psychiatre et chercheuse spécialisée dans l'utilisation des psychédéliques pour le traitement de la santé mentale

Mon site internet personnel est en ligne !

lucie-berkovitch.fr/fr

Il rassemble mes publications, interventions en congrès ou dans les médias, et les éléments principaux de mon parcours🎢

🌈 Vous verrez, je me suis fait plaisir avec les liens cliquables qui ont une petite touche #psychédélique !

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1 month ago
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My personal website is now live!

lucie-berkovitch.fr/en

It showcases my publications, talks, and media interviews, as well as the key milestones of my career 🎢

🌈 You'll see that I had fun with the clickable links, which have a slightly #psychedelic touch!

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2 months ago

Et au passage je vous souhaite à toutes et à tous une très belle année 2026 ✨

🎧 Bonne écoute !

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2 months ago

L'occasion d'aborder les contrevérités circulant sur ces substances et de souligner leur potentiel thérapeutique 💊

Un grand merci à @quentinlafay.bsky.social, @juliettemouellic.bsky.social et à toute l'équipe !

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2 months ago
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Champignons, LSD : un espoir pour la psychiatrie ? Les recherches sur les psychédéliques avancent et interrogent. Ces substances, longtemps interdites, sont de nouveau utilisées pour traiter les souffrances de patients touchés par une dépression, ou e...

🌚 Questions du soir, bonjour ! @questionsdusoir.bsky.social

🎙️ Emission de rentrée consacrée aux #psychédéliques en direct hier sur @franceculture.fr en compagnie de @vincent-verroust.bsky.social de la Société psychédélique française @psychedelique-fr.bsky.social
www.radiofrance.fr/francecultur...

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4 months ago

💊 We conclude that ketamine may induce psychotic-like symptoms by disrupting consciousness.

📣 Please enjoy, share, and give feedback!

Many thanks to my colleagues who supported me in this epic tale!
Raphaël Gaillard, @standehaene.bsky.social, @thomasandrillon.bsky.social and Alexandre Salvador

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4 months ago
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👀 We used a visual masking paradigm and found that healthy volunteers under ketamine were less able to perceive a digit.

🧠 These effects were related to a decreased early brain activity in EEG (N1) and to the intensity of experienced psychotic-like symptoms.

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4 months ago
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Ketamine disrupts consciousness in healthy participants in relation with psychotic-like symptoms Ketamine is an NMDA-receptor antagonist, which alters the state of wakeful consciousness at high doses. At lower doses, it induces reversible psychotic-like symptoms and has been used as a pharmacolog...

" #Ketamine disrupts #consciousness in healthy participants in relation with #psychotic-like symptoms"

🥸 This is the title of our last preprint @biorxiv-neursci.bsky.social giving some insights on how ketamine at subanesthetic doses mimicks psychosis symptoms!

www.biorxiv.org/content/10.1...

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6 months ago

Thank you so much @haunted.audio, it is an amazing series!

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6 months ago

This amazing series by Tim Hayward and Richard Ward @haunted.audio (🙏🙏🙏) also featured renowned neuroscientists such as @christimmermann.bsky.social, @katrinpreller.bsky.social, Gul Dölen, as well as nurses, historians, philosophers, sociologists, etc.

Enjoy! 🎧

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6 months ago
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BBC Radio 4 - Understand, The Trip, 10. Unknown unknowns What more is there to learn about psychedelics? Tim Hayward makes a case for curiosity.

In the first episode, I explain what is specific about psychedelics as treatment in psychiatry.
In last episode, dealing about the future of psychedelics, I talk about the possible dissociation between the psychedelic experience and the therapeutic effects:

www.bbc.co.uk/programmes/m...

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6 months ago

🎙️ I am very proud to have participated (with a very strong French accent) to the BBC Radio 4 program Understand entitled "The Trip", about the science, culture, history and future of psychedelics 🌈

www.bbc.co.uk/programmes/m...

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6 months ago
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A few moments from our ongoing MESEC 2025 Workshop (‘Centering Experience in Mental Health: Uniting Psychiatry and Consciousness Science’) at the beautiful Lago di Bolsena!

@lucieberko.bsky.social
@tehseennoorani.bsky.social

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6 months ago
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Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia Abstract. Disruption of conscious access contributes to the advent of psychotic symptoms in schizophrenia and could also explain lack of insight in other p

🚨 New article in #NCONSC

Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia
academic.oup.com/nc/article/2...

@lucieberko.bsky.social

#consciousness
🧠🧪

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6 months ago

🙏 A huge thanks to my co-authors Selim Tümkaya, Bengü Yücens, Mohamed Gunduz and Maxime Maheu @maheump.bsky.social

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6 months ago

In sum :
✅ Consciousness disruption translates into various symptomatic expressions according to the psychiatric disorder
✅ In patients with OCD, consciousness disruption delineates two distinct subgroups in terms of cognitive deficits and clinical features

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6 months ago

‼️ Patients with SCZ have consciousness disruption in relation with positive symptoms
‼️ Patients with OCD who have a poor insight exhibit similar consciousness deficits as patients with schizophrenia
‼️ Patients with OCD and good insight performed similarly to controls ⤵️

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6 months ago

We compared consciousness measures in patients with #OCD and with #schizophrenia as a function of symptom relevant dimensions.

😮 We found pretty surprising results: ⤵️

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6 months ago
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Disruption of consciousness depends on insight in obsessive-compulsive disorder and on positive symptoms in schizophrenia Abstract. Disruption of conscious access contributes to the advent of psychotic symptoms in schizophrenia and could also explain lack of insight in other p

🗞️ First article as #lastauthor published in Neuroscience of Consciousness @nconsc.bsky.social 🥳 🥳 🥳

academic.oup.com/nc/article/d...

🔍 In this study, we examine how #consciousness disruption translates into clinical manifestations in different #psychiatric disorders. 🧶⤵️

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6 months ago
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Les substances hallucinogènes peuvent-elles soigner l’alcoolisme et la dépression ? La dépendance à l’alcool serait, selon le ministère de la Santé, responsable chaque année de 49 000 décès. Mais selon une étude menée par le CHU de de Nîmes, les champignons hallucinogènes pourraient ...

Berko on air de bon matin sur @franceculture.fr

www.radiofrance.fr/francecultur...

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6 months ago

Thanks to all my collaborators!!

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6 months ago

Overall, our results underscore that a univariate data-driven symptom improvement measure can be more sensitive to detect antidepressant action and is specifically associated with baseline neurobehavioral features.

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6 months ago
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Moreover, improvement was more robustly predicted by baseline neural and clinical features under antidepressant compared to placebo.

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6 months ago
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However, the intensity of antidepressant and placebo response significantly differs (in previous papers on this dataset, scale level measures of improvement could not distinguish between the two).

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6 months ago
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We applied principal component analysis (PCA) on the variations of items from multiple clinical scales and strikingly observed a similar pattern of clinical improvement across antidepressant and placebo arms.

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6 months ago
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We explored clinical response in patients with major depressive disorder from the EMBARC dataset.

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6 months ago
A common symptom geometry of mood improvement under sertraline and placebo associated with distinct neural patterns | Psychological Medicine | Cambridge Core A common symptom geometry of mood improvement under sertraline and placebo associated with distinct neural patterns - Volume 55

New paper out in Psychological Medicine where we found that #sertraline and #placebo strikingly induce a similar clinical improvement predicted by distinct neural configurations!

doi.org/10.1017/S003...

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9 months ago

A big thank to my colleagues Baptiste Fauvel, @katrinpreller.bsky.social and Raphaël Gaillard

Please find here the link for free access until 27th of July:
authors.elsevier.com/a/1lE1NY3M3l...

Enjoy!!

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9 months ago

🧠 No fewer than 81 articles are described in depth and put together to provide an overview of the neurocognitive effects of psilocybin in healthy volunteers and people with medical conditions.

😅 Believe me, it was quite a long journey before it was published in Neuroscience & Biobehavioral Reviews!

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9 months ago
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Neurocognitive effects of psilocybin: A systematic and comprehensive review of neuroimaging studies in humans Psilocybin is a psychedelic serotonergic compound that is renowned for its potent psychoactive effects. Over the past 15 years, an increasing number o…

📚 Just another #review about #psychedelics? Maybe... but in this paper we systematically reviewed ALL neuroimaging articles involving #psilocybin intake in humans.
www.sciencedirect.com/science/arti...

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