Martin Grininger

With our research, we are one step closer to biotechnological palm oil alternatives 🌱
rdcu.be/e2nbH

📺📻 Featured on TV, radio, and online media, e.g.:
www.tagesschau.de/inland/regio...

#Sustainability #GreenBiotechnology #Biotechnology #SyntheticBiology #MetabolicEngineering #PalmOil #PalmOilFree

From Palm Oil to Designer Enzymes: Frankfurt Researchers Reprogram Yeast Cells | Aktuelles aus der Goethe-Universität Frankfurt Protein Engineering Enables Sustainable Production of Industrially Important Fatty Acids Fatty acids derived from palm oil and coconut oil are found in countless everyday products, but their extractio...

Thanks @goetheuni.bsky.social for featuring our work in fatty acid synthase engineering! A culmination of years of shared effort ✨
aktuelles.uni-frankfurt.de/english/from...

Happy to have contributed to this issue! doi.org/10.1016/j.ti...

Short fatty acids, custom synthesized by engineered yeast 🧫
Here it is: doi.org/10.1038/s415...

🤝✨ Fantastic team effort — thanks to Yongjin Zhou!
Science made possible at @goetheuni.bsky.social 🏛️🔬

Design of a Multienzyme Derived from Mouse Fatty Acid Synthase for the Compartmentalized Production of 2‐Pyrone Polyketides A multienzyme was formed and evaluated by covalently linking 4-coumarate ligase (4CL1) from Piper methysticum to a non-reducing murine fatty acid synthase. 4CL1 acylates the acyl carrier protein (ACP....

New in Angewandte 🔥: With two engineered changes, we reprogram mammalian fatty acid synthase to make pyrones instead of fatty acids! 🧬 Congrats Felix, Nadja & Caro! We delete the processing part + tweak the KS pocket, even mimicking PKS-like initiation. Paper: doi.org/10.1002/anie...

Great meeting in Shenzhen by @asm.org and SIAT! Really appreciated the microbiology insights — amazing how central microbes are to so many of today’s challenges. @vscooper.micropopbio.org @rebeleinlab.bsky.social @helgebode.bsky.social @friedrich-group.bsky.social
www.greeninger-chemistry.com/

📝 Online now - the Review "Molecular mechanisms of the mammalian fatty acid cycle" from Christian Gusenda and @m-grininger.bsky.social.

#FattyAcidBiosynthesis #FattyAcidSynthase #FAS #mFAS #AcylCarrierProtein #ACP

Read it here 👉 authors.elsevier.com/sd/article/S...

📣 Open call for a Full Professorship (W3) in Organic Synthesis.

🌍 University Frankfurt, Germany

🗓️ Application Deadline approaching: 23rd of May

Join one of Germany’s leading universities. @goetheuni.bsky.social #ScienceCareers #JobOpportunity #FacultyPosition #OrganicChemistry

Excited to share my first post on Bluesky: I’ve recently been appointed as a Professor at Goethe University Frankfurt! 🎉

The Stephan Lab will use advanced bioimaging 🔬🧫 to explore how organelles collaborate to maintain subcellular architecture and metabolism.

Professor (W3) in Organic Synthesis - Frankfurt am Main, Hessen (DE) job with Johann Wolfgang Goethe-Universität Frankfurt | 12838450 Goethe University Frankfurt am Main invites applications for the position of Professor (W3) in Organic Synthesis at the Faculty of Biochemistry, Ch...

📢 The University of Frankfurt (Germany) is hiring a Full Professor in Organic Synthesis

-->Cutting-edge research in an open, collaborative environment? Check out the call and join one of Germany’s leading research universities.

#AcademicJobs #FacultyPosition

www.nature.com/naturecareer...

Design principles imprinted by evolution Nature Chemical Biology - Redesigning polyketide biosynthesis to either derivatize polyketides or develop new ones is highly desirable, but engineered pathways usually suffer from low product...

🚗💥 Henry Ford’s car assembly line is the perfect analogy for how nature builds polyketide natural compounds. But can we rearrange nature's assembly lines to make novel polyketides?

🔬 Recent breakthroughs are promising 📖 Read my perspective on how this vision is becoming reality.

rdcu.be/ei12O