Danny

Detecting Protein-DNA binding in single molecules using antibody guided methylation - Epigenetics & Chromatin Characterization of DNA binding sites for specific proteins is of fundamental importance in molecular biology. It is commonly addressed experimentally by chromatin immunoprecipitation and sequencing (...

Our ChAMP paper is out!
epigeneticsandchromatin.biomedcentral.com/articles/10....

02.07.2025 08:10 — 👍 0    🔁 0    💬 0    📌 0

information loss in the liver. Thanks to the
Goldstein lab that provided much of the data and the ChIP-seq analysis. biorxiv.org/content/10.1...

P.S. the preprint isn't really new, but you aren't following me on twitter, so it's new for you.

14.06.2025 19:04 — 👍 1    🔁 0    💬 0    📌 0

and some diseases. Here, we show that these sites causally contribute to aging: both pathogenic SNPs and causal epigenetic clocks (DamAge) are enriched for these sites. Information loss is also reversible: in mice, repeated fasting (but not a single fast) reverses this 2/3

14.06.2025 19:04 — 👍 0    🔁 0    💬 1    📌 0

Our preprint "Reversible and Causal Epigenetic Information Loss in Liver Aging and Disease" is out! We've previously shown that looking at methylation sites that are very different in one tissue from all others allows us to observe epigenetic information is loss upon aging 1/3

14.06.2025 19:04 — 👍 2    🔁 0    💬 1    📌 1

Woodstock.bio2 & Night Science 2025 playlist Playlist · Vojtěch Svoboda · 99 items · 2 saves

open.spotify.com/playlist/1As...

13.06.2025 11:51 — 👍 9    🔁 3    💬 0    📌 2

Where can I buy the official CD? #TCTeAC

13.06.2025 08:37 — 👍 17    🔁 2    💬 2    📌 0

#TCTEAC

12.06.2025 19:50 — 👍 1    🔁 0    💬 0    📌 0

12.06.2025 19:48 — 👍 3    🔁 0    💬 1    📌 0

Fun fact - this was the inspiration for the review process in journal XXX.

12.06.2025 09:34 — 👍 1    🔁 0    💬 0    📌 0