#VAMP7-dependent late endosomal #secretion of #ER and #mitochondrial proteins impacts the #tumor #microenvironment and #macrophage engagement
www.nature.com/articles/s41...
Our article on how to use micropatterned presynapses-on-glass is out in its final form in the latest issue of the Journal of Neuroscience @sfnjournals.bsky.social: www.jneurosci.org/content/46/8...
The cover went to the special section on social neuroscience, so here's our #notthecover attempt
Gotta love Nature's opinion pieces
"Science funding needs fixing - but not like that"
"Academic publishing is broken - but publishing less is not the solution"
"AI will kill science - how can researchers use it to be more efficient?"
FCHo2, not talin, enables inside-out activation of integrin ΙvΞ²5 in curved adhesions
www.nature.com/articles/s41...
A menagerie of COS cells for #MicroscopyMonday π§ͺ
My personal obituary for Richard Hynes now live on the Manchester Cell-Matrix Centre website. www.manchester-matrix.org/news/profess...
This is finally out in J Neuroscience! A micropatterned presynapse-on-glass approach to resolve the nanoscale architecture and function of presynapses
www.jneurosci.org/content/earl...
Excited to share our work engineering caveolin-derived nanoparticles βcaveospheresβ. We show their use for targeted transfection in cultured cells and effective targeted delivery and tumor killing in vivo.
pubs.acs.org/doi/full/10....
π¨The Neurocyto lab is branching out in our latest preprint! We used tubulin microinjection to directly visualize microtubule turnover in developing hippocampal neurons, demonstrating the presence of in-lattice repair and a selective stabilization in the nascent axon. Check below, or read on 𧡠1/9
Latest paper is now out and features on the cover of Science Advances π tinyurl.com/vea5862x
Very grateful Igor Bonacossa Pereira, Dat Le & Massimo Hilliard @hilliardlab.bsky.social for their creativity & passion.
Read more about it π
tinyurl.com/56awjda5
& π tinyurl.com/2vp8p8uk
What a great start for 2026 for the EVICAT team!!!
Everything you need to know about extracellular vesicles' recipient cells and how to harness these pathways for therapeutic purposes
Thanks to all co-authors!
bit.ly/3N9InyW
A tribute to Stuart Kornfeld, pioneering #glycotime scientist whose work on mannose-6-phosphate receptor lysosomal trafficking (among many other contributions) was highly influential to our work π«‘
www.jci.org/articles/vie...
New paper out!
We show how mechanosensitive adherens junction proteins link actomyosin contractility to actin assembly using in vitro reconstitution.
Huge congrats to AurΓ©lie Favarin, Rayan Said, & all authors!
In Science Advances: www.science.org/doi/10.1126/...
#actin #myosin #mechanobiology
Optogenetic SH3 nanoclustering of SRC and HCK uncovers the functional specificity of these redundant kinases in macrophages. https://www.biorxiv.org/content/10.64898/2025.12.27.692121v1
A comprehensive article for our unique Live-to-HPF CLEM workflow in Scientific Reports!π¬βοΈ Thanks to all who supported our long journey!
Images are taken @ImagoSeine @ijmonod.bsky.social @imagerie-gif.bsky.social @i2bcparissaclay.bsky.social @jeoleurope.bsky.social
www.nature.com/articles/s41...
@natcellbio.nature.com - Finally out! Skin cells mechanically protect their genome from UV by positioning melanin above nucleus. Keratin filaments & microtubules drive the process. Led by Silvia Benito-Martinez & @laurasalavessa.bsky.social @membramics-lab.bsky.social www.nature.com/articles/s41...
#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musΓ©e d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.
Today, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published:
journals.biologists.com/jcs/article/...
The result of a fantastic Iwasa-Drubin lab collaboration.
@margotriggi.bsky.social @jiwasa.bsky.social
movie.biologists.com/video/10.124...
Great collaborative work led by Christopher Toepfer and his team at the University of Oxford
is there a direct crosstalk between actin and vimentin intermediate filaments? Our work shows that vimentin promotes actin assembly by stabilizing ATP-subunits at the barbed end.
Fantastic work done by @lilianpaty.bsky.social with @romet-jegou-lab.bsky.social
www.biorxiv.org/content/10.1...
I am thrilled to share our new article entitled 'Alternative splicing of SORBS1 affects neuromuscular junction integrity in myotonic dystrophy type 1 onlinelibrary.wiley.com/doi/10.1002/...
@cecilemartinat.bsky.social
PhD student management tip from his advisor RenΓ© Couteaux, discoverer of the neuromuscular junction: "*points at 50 cm of lab bench* here's where you'll work. I'll be back in three months to see what you've done"
I'm at the French Society for Myology meeting with @stefvass.bsky.social! He just made a book about the late Michel Fardeau, first president of the society, pioneer of electron microscopy for muscle and muscle disease
en.wikipedia.org/wiki/Michel_...
Want to hear a mid-career PI pontificate about science, career and cooking? Today's your lucky day thanks to The Microscopists podcast! Thanks Peter @yorkbioimaging.bsky.social for having me ποΈπ§
themicroscopists.bitesizebio.com/episodes/chr...
New NeuroCyto preprint about to drop! @wiesner-t.bsky.social πβ³
www.sciencedirect.com/science/arti...
check out the recent dispatch on endolysosomes and melano-biology interplay in @currentbiology.bsky.social by @delevoyecedric.bsky.social & @laurasalavessa.bsky.social from @membramics-lab.bsky.social
If you're interested in trafficking of #myelin constituents in #oligodendrocytes, and of course you are, you may want to check out our new preprint. It's very nice PhD work by @sophiesiems.bsky.social, and we're grateful to all who contributed!
www.biorxiv.org/content/10.1...
Happy to contribute to this new work from @micoxscopy.bsky.social et al, helping apply SSQUASH to analyse the shape of spectrin rings along axons. Data analysis is the next frontier in SMLM, and I'm always up for chatting, sharing data and see how we can push things further!
how did I miss this fantastic paper...congrats Marko @kaksonen.bsky.social and team!!
Diving into "le AIS"π€Ώ
