Delighted to share our new collaborative study led by Anne Mette Madsen (nfa.dk) on microbial & dust exposures in waste-recycling workers and links to inflammation. sciencedirect.com/science/articl… #EXIMIOUS (eximious-h2020.eu)

Delighted to be able to share (Early View) our new paper “Molecular endotyping in people with bronchiectasis based on response to antibiotic treatment: iBEST study” in ERJ Open Research publications.ersnet.org/content/erjor/… #Bronchiectasis #qPCR #Microbiome #endotype

Delighted to be a part of this and being able to share the Early View of our multi-centre CFMATTERS study in ERJ (@ERSpublications)!
Can microbiome-guided antibiotics improve PEx treatment in pwCF?
🔗 doi.org/10.1183/139930…
�� cfmatters.s.eu
#CF #Microbiome #Antibiotics #CFMATTERS

Fantastic to see the CF-Tracker study taking off!

Looking forward to hear more about this very interesting study in the future!

tunney PhD Projects, Programmes & Scholarships FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in tunney. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.

Three fully funded PhD’s available!
Looking for talented applicants with microbiology experience to study the role of microbes in cystic fibrosis exacerbations as part of the PULSE-CF Innovation Hub www.pulse-cf.com

Find out more and apply at: go.qub.ac.uk/CFPhDs

Gutting the CDC right as we’re on the cusp of major outbreaks of transmissible diseases is a very bad idea.

Delighted to be presenting our poster on “Beyond the cuff - characterising biofilm-forming microorganisms on endotracheal tubes in critically ill patients” at the #RTI2025 in Glasgow a project funded by Northern Ireland Chest Heart and Stroke @nichstweets

Great PhD opportunity as part of a large and exciting new research hub in cystic fibrosis! More info below or www.pulse-cf.com

Our second presentation within the Infection and Antimicrobial Resistance theme is by
Thomas Thompson on 'Harnessing Cold Plasma to Combat Biofilm-Associated Infections'

At our second monthly joint meeting within the Infection and Antimicrobial Resistance theme here at the School of Pharmacy QUB we kick off with our first ever presentation within the theme by Caitlin Miskelly: ‘Developing mucosal vaccines against the ESKAPE pathogens’

Airway total bacterial density, microbiota community composition and relationship with clinical parameters in bronchiectasis This study explored the relationship between total bacterial density, airway microbiota composition and clinical parameters in bronchiectasis. We dete…

Delighted to be a part of this recent paper led by Zina Alfahl and colleagues from the BRONCH-UK Clinimetrics Study (bronchiectasisuk.hicservices.dundee.ac.uk/clinimetrics...) on Bronchiectasis published in Respiratory Medicine
sciencedirect.com/science/arti....
@qubelfastofficial.bsky.social

University of Birmingham, Department of Microbes, Infections and Microbiomes PhD Projects, Programmes & Scholarships FindAPhD. Search Funded PhD Projects, Programmes & Scholarships at University of Birmingham, Department of Microbes, Infections and Microbiomes.

If you want to join the group then multiple opportunities available at the moment. If you don't like what we do then we've got you covered there too! Funded PhD projects for UK and Overseas students in our Department here www.findaphd.com/phds/departm... come and join a lovely bunch of talented PGRs

Macrophages and the microbiome in chronic obstructive pulmonary disease COPD is a heterogeneous disease of the lungs characterised by restricted airflow. Chronic inflammation and recurrent bacterial infections are known to be important driving factors in exacerbations of this disease. Despite a marked increase in the number of alveolar macrophages present in the lungs of COPD patients, there is evidence of reduced clearance of pathogenic bacteria, leading to recurrent infection, exacerbation and subsequent lung function decline. This is thought to be attributed to a defect in the phagocytic capability of both alveolar and monocyte-derived macrophages in COPD. In addition to this defect, there is apparent selectivity in bacterial uptake by COPD macrophages because certain pathogenic genera, such as Haemophilus, Moraxella and Streptococcus, are taken up more readily than others. The respiratory microbiome plays a key role in regulating the host immune response both in health and during chronic inflammation. In patients with COPD, there are distinct changes in the composition of the respiratory microbiome, particularly the lower respiratory tract, where dominance of clinically relevant pathogenic species is commonly observed. Whether there are links between these changes in the microbiome and dysfunctional macrophage phagocytosis has not yet been widely studied. This review aims to discuss what is currently known about these phenomena and to explore interactions between macrophages and the respiratory microbiome.

Publication day for us and a very first, first author review for Karanjot Sandhu 🥳 publications.ersnet.org/content/erre...
Karan's summarised the respiratory microbiome in COPD, the importance of macrophages in the disease and how we think these might be interacting with each other.

📢 #PhD Opportunity 3! Investigate how the airway microbiome shapes pulmonary exacerbations in pwCF. Join us @qubelfastofficial.bsky.social to uncover the links between microbial dynamics and clinical outcomes. 🧬🌬️ Apply here: tinyurl.com/2bmm3yqn

#PhD #Microbiome #CF #CFResearch #PULSECF

#PhD Opportunity 2! Explore enhanced microbiological surveillance in pwCF. Join @qubelfastofficial.bsky.social cutting-edge PULSE-CF initiative to improve understanding and management of CF-related infections.🌟Learn more & apply: tinyurl.com/27o2purp
#PhD #Microbiology #CF #CFResearch #PULSECF

💡 Exciting #PhD Opportunity 1! Dive into the role of polymicrobial communities in #CF airways and their impact on infection & pulmonary exacerbations. Join us and contribute to cutting-edge research on chronic respiratory disease. 🌟 Learn more & apply: tinyurl.com/2676cbld

PULSE-CF is led by Prof. Alex Horsley from @official-uom.bsky.social and Manchester CF and Prof. Michael Tunney (tinyurl.com/28njlxx5) here @qubelfastofficial.bsky.social and is a CF Innovation Hub aiming to better understand and prevent exacerbations in CF. Here at QUB we have three PhD on offer!

PULSE-CF

Thrilled to be part of the upcoming PULSE-CF study! 🌟 This ground-breaking research aims to unravel the complexities of polymicrobial communities in the CF airways and their role in pulmonary exacerbations.

Learn more: www.pulse-cf.com

#CF #Microbes #Viruses

Microbiome ecology approaches reveal bacterial interactions underpin worse lung function in #CysticFibrosis

#CF Lung infections are not caused by 1 pathogen in isolation but instead by interplay of complex lung microbiota of many different microbes interacting with each other & the lung environment

Very interesting study focused on co-occurrence between taxa, many “non-pathogens”, and how they are linked to poorer lung function. Chronic lung infections in #CF are more complex than just single pathogens!

The two best boys!