Stuart Oldham

Postdoctoral Research Associate (Physics) Full time, 2-year fixed term position with potential to extend. Located on the Camperdown Campus at the School of Physics. Exciting opportunity to conduct research in a world-leading interdisciplinary...

Are you interested in our work on complex physical systems and applications (to neural systems)?

Wanna join us in Sydney? 🐨 🦘

We have two open positions:

1. Postdoc position: usyd.wd105.myworkdayjobs.com/USYD_EXTERNA...

2. Fully-funded PhD position: www.sydney.edu.au/scholarships...

Personalized Adaptive Cortical Electro-stimulation (PACE) in Treatment-Resistant Depression

Punchline: PERSONALIZED network neuroscience works.

*Easily* the most important paper I’ve been part of.

Read the manuscript for details. Watch the movies for *amazing* testimonial.

1/2

Spatial transcriptomics reveals human cortical layer and area specification - Nature Multiplexed error-robust fluorescence in situ hybridization (MERFISH) together with deep-learning-based nucleus segmentation enabled the construction of a highly detailed and informative spatially res...

Spatial transcriptomics reveals human cortical layer and area specification www.nature.com/articles/s41... - early emergence of layers; graded differentiation along A/P axis, w/ early, sharp V1/V2 boundary

New paper in Imaging Neuroscience by Kane Pavlovich, Alex Fornito, et al:

The efficacy of resting-state fMRI denoising pipelines for motion correction and behavioural prediction

doi.org/10.1162/IMAG...

New Method Is the Fastest Way To Find the Best Routes | Quanta Magazine A canonical problem in computer science is to find the shortest route to every point in a network. A new approach beats the classic algorithm taught in textbooks.

For the first time in four decades, a new algorithm has improved upon the speed limit for calculating the fastest route to every point in a network. @benbenbrubaker.bsky.social‬ reports: www.quantamagazine.org/new-method-i...

Integrating and interpreting brain maps | doi.org/10.1016/j.ti...

Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️

CogSci 2025 The 47th Annual Meeting of the Cognitive Science Society presents the latest research across cognitive science and highlights the theme of Cognition in Context.

At 18:30 UK time, I will be presenting my work on learning and exploration across development at the @cogscisociety.bsky.social Glushko Dissertation Prize Session! #CogSci participants can join at this link: underline.io/events/489/s...

Interested in cortical wave dynamics? Check out our new preprint led by J Cruddas with @jchrispang.bsky.social where review the physics and physiology of cortical waves and their implications for psychological function:

osf.io/preprints/ps...

@nsb-lab.bsky.social

Updated version of this preprint, with brand new title and everything: www.biorxiv.org/content/10.1...

An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus - Nature Neuroscience The topographical organization of cells in the hippocampus reflects its ability to regulate mood and cognition. Here the authors generate a spatially resolved gene expression map in the human hippocam...

Great resource, out today in @natneuro.nature.com:
An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampus
@stephaniehicks.bsky.social @martinowk.bsky.social & colleagues
🧪🧠🧬
www.nature.com/articles/s41...

Research Officer Job in Parkville, Melbourne VIC - SEEK We are seeking a Postdoctoral Research Officer to drive international neuroimaging research into childhood NF1 brain development.

JOB ALERT! We're seeking a postdoctoral scientist to join Developmental Imaging at @mcri.bsky.social in Melbourne.

Role will involve working with international partners on a new project charting brain growth in children with NF-1

Please reach out for more information

www.seek.com.au/job/86090834

Brain Surfaces of 70 primate species

1
To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!

🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

Better version of the meme.

4-panel comic. (1) [Person 1 with ponytail flanked by person with short hair and another person speaking into microphone at podium] PERSON 1: In the early 2010s, researchers found that many major scientific results couldn’t be reproduced. (2) PERSON 1: Over a decade into the replication crisis, we wanted to see if today’s studies have become more robust. (3) PERSON 1: Unfortunately, our replication analysis has found exactly the same problems that those 2010s researchers did. (4) [newspaper with image of speakers from previous panels] Headline: Replication Crisis Solved

Replication Crisis

xkcd.com/3117/

Fab new work from @kanepav.bsky.social with @jchrispang.bsky.social looking at how different measures of inter-regional FC are resistant to motion-related noise and how they can improve (or not) BWAS effect sizes. Peep the thread!

The Motion Sensitivity and Predictive Utility of Different Estimates of Inter-regional Functional Coupling in Resting-state Functional MRI. Numerous methods exist for quantifying statistical dependencies, termed functional coupling (FC), between regional brain activity recorded with resting-state functional magnetic resonance imaging (rs-...

New pre-print from @alexfornito.bsky.social, @jchrispang.bsky.social, and myself looking at the sensitivity of different methods used to estimate FC/EC in relation to residual motion artifacts and behavioural prediction
www.biorxiv.org/content/10.1...

New 2 year position as an Imaging Data Infrastructure Specialist

Located a the Hunter Medical Research Institute (HMRI) & the University of Newcastle (UoN), in partnership with the National Imaging Facility (NIF),

Apply here: www.seek.com.au/job/85537666

Frontiers | Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness IntroductionConsciousness relies on both cortical and subcortical structures and their feedforward and feedback pathways. Within this framework, the thalamus...

Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness

www.frontiersin.org/journals/neu...

Barcoded Rabies In Situ Connectomics for high-throughput reconstruction of neural circuits Sequencing of oligonucleotide barcodes holds promise as a high-throughput approach for reconstructing synaptic connectivity at scale. Rabies viruses can act as a vehicle for barcode transmission, than...

1/ Mapping synaptic connectivity between individual neurons is extremely laborious. We developed BRISC, a new method that makes it possible to map inputs onto 100s of neurons in the same animal in a matter of weeks! Led by Alex Becalick and @antblot.bsky.social. 🧵

www.biorxiv.org/content/10.1...

Have you been using ABCD data? Are you measuring psychopathology with the CBCL? You will want to check out our latest preprint, led by @kanepav.bsky.social, which shows that the constructs measured by the tool fail to meet many basic validity tests. Peep the thread!

GitHub - dionnecargy/melbourne: A package love letter to Melbourne A package love letter to Melbourne. Contribute to dionnecargy/melbourne development by creating an account on GitHub.

Have you ever been transfixed by the colour palette of the Melbourne tram network?

Well I have... so I made a package called {melbourne}! So far it includes a colour palette called "melb_trams()". More to come, stay tuned!

🔗 Check it out: github.com/dionnecargy/...

#RStats #DataScience #Rcoding

1000s of studies have been published mapping neuroanatomical changes in psychiatric disorders. Can we ever converge on robust disease phenotypes? Our latest PP led by Trang Cao in a huge collab effort investigates this question...

@nsb-lab.bsky.social

Competing Programs Shape Cortical Sensorimotor-Association Axis Development The neocortex is organized along a dominant sensorimotor-to-association (S-A) axis, anchored by modality-specific primary sensorimotor areas at one end and transmodal association areas that form distr...

Thrilled to present MIND!

A model for how the sensorimotor–association axis of the neocortex develops.

Huge thanks to the incredible multidisciplinary team who made this happen.

www.biorxiv.org/content/10.1...

Latest work from the Sestan lab exploring the development of cortical organisation along the sensorimotor-association axis.

Using developmental transcriptomics, in vivo genetic models, viral circuit tracing, histology, neuroimaging & more —across species. Something for everyone, hopefully!

I really cooked with this one

How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...

Good morning folks. If you’re around #OCNS2025, maybe come by today for a chat about optimal communication in brain networks? ✨

The OHBM Time Machine places all recorded talks/sessions from OHBM annual meetings onto YouTube *for free*.

Sessions from 2015-2024 are available to watch now, with 2025's recordings coming in the next couple of months - watch this space.

Explore the time machine yourself: www.youtube.com/@OHBM

🚨 Apply NOW for the 2025 Neuro–Irv & Helga Cooper Foundation Open Science Prizes!
Rewarding #OpenScience in neuroscience - the Tanenbaum Open Science Institute

💡 $80K Main Prize
🎓 $10K Intl. Trainee Prize
🍁 $5K Canadian Trainee Prize

🔗 www.mcgill.ca/neuro/open-s...)
🗓️ Aug 15

New preprint!

Why are long-range connectomic interactions in the cortex dominant in shaping dynamics in some experiments but apparently negligible in others?

We (w/ R Maran, @elimuller.bsky.social) address this question by studying a new hybrid model of cortical dynamics.

arxiv.org/abs/2506.19800