Kayson Fakhar

Congrats 🥳🎉

Or… MORE TASKS

🚨 Fresh preprint w/ @helenblank.bsky.social!

How does the brain acquire expectations about a conversational partner, and how are priors integrated w/ sensory inputs?

Current evidence diverges. Is it prediction error? Sharpening?

Spoiler: It's both.👀

🧵1/16

www.biorxiv.org/content/10.1...

Love these exhaustive type of works that lay out all possible combinations of something and leave no room for another “what if”

A neural manifold view of the brain - Nature Neuroscience Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds. Understanding how nature, nurture...

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world!

🔗: www.nature.com/articles/s41...
📄: rdcu.be/ex8hW

There’s a whole page full of these

The future of science communication has arrived.

Brain Surfaces of 70 primate species

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To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised!

🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

Brain wiring economics, network organisation and population-level genomics Abstract. What role do our genes play in shaping the structural organisation of the living human brain? Across a sample of 2,153 children (9–11 years old), we address this question, focusing on common...

*New Paper* How genes for IQ shape brain organisation. Amazing work led by Alicja Monaghan @mrccbu.bsky.social reveals 2 ways. First, they’re associated w/ the ‘costs’ of network formation. Second, they define ‘high value’ areas within the network. How she did it…🧵
doi.org/10.1162/IMAG...

GitHub - hsayama/PyCX: PyCX is a Python-based sample code repository for complex systems research and education. PyCX is a Python-based sample code repository for complex systems research and education. - hsayama/PyCX

I finally had time to update PyCX to ver. 1.2! Many new models and bug fixes. Enjoy!!
github.com/hsayama/PyCX

Description Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

Hiring a post-doc at Imperial in EEE. Broad in scope + flexible on topics: neural networks & new AI accelerators from a HW/SW co-design perspective!

w/ @neuralreckoning.bsky.social @achterbrain.bsky.social in Intelligent Systems and Networks group.

Plz share! 🚀: www.imperial.ac.uk/jobs/search-...

How can we best use AI in science?

Myself and 9 other research fellows from @imperial-ix.bsky.social use AI methods in domains from plant biology (🌱) to neuroscience (🧠) and particle physics (🎇).

Together we suggest 10 simple rules @plos.org 🧵

doi.org/10.1371/jour...

🔥🔥🔥🔥🔥

Congrats! 1/5th is done ✅

Beyond Rate Coding: Surrogate Gradients Enable Spike Timing Learning in Spiking Neural Networks We investigate the extent to which Spiking Neural Networks (SNNs) trained with Surrogate Gradient Descent (Surrogate GD), with and without delay learning, can learn from precise spike timing beyond fi...

New preprint for #neuromorphic and #SpikingNeuralNetwork folk (with @pengfei-sun.bsky.social).

arxiv.org/abs/2507.16043

Surrogate gradients are popular for training SNNs, but some worry whether they really learn complex temporal spike codes. TLDR: we tested this, and yes they can! 🧵👇

🤖🧠🧪

Genetic foundations of interindividual neurophysiological variability Individual brain activity profiles are shaped by lifelong genetic influences.

🧬🧠 Our latest study shows that individual brain dynamics are partly written in our genes. We found that heritable neurophysiological traits align with adult cortical gene expression and psychological function.

www.science.org/doi/10.1126/...

@theneuro.bsky.social @mcgill.ca

We are hiring for several research positions for this grant, starting early next year. Please reach out if you're interested!
More details on the jobs here: devcompsy.org/wp-content/u...

Deadline for this funded PhD to work with me and @duncanastle.bsky.social is soon! 26 July.

The student must be a woman (because it’s based at Newnham College) and eligible for UK home fees.

Mapping human thalamocortical connectivity with electrical stimulation and recording - Nature Neuroscience Intracranial stimulation maps human brain causal connectivity, uncovering distinct pathways. The authors show that thalamic pulses uniquely evoke delayed theta oscillations, offering new insights into...

Stimulating and recording with intracranial electrodes implanted in cortical regions and thalamic nuclei across 4,864 sites in 27 human participants reveals distinct spectral signatures elicited by perturbations of specific brain areas

www.nature.com/articles/s41...

“Top-down and bottom-up neuroscience: overcoming the clash of research cultures”
doi.org/10.1038/s415...
Small contribution in this piece by @frosas.bsky.social and colleagues on how we need both types of research culture in neuroscience.
#neuroskyence

What drives the self-organization of life? By linking three major ecological theories, we show that ecosystems maximize power at intermediate efficiency close to bifurcation points. Energy flux meets life's organizing principles. @sfiscience.bsky.social www.biorxiv.org/content/10.1...

Concern About Predictive Performance of a Pain Sensitivity Biomarker To the Editor Chowdhury et al1 evaluated a biomarker for pain sensitivity, combining peak alpha frequency and corticomotor excitability. The authors report outstanding performance (validation set area...

Serious concerns about a new cortical biomarker for pain sensitivity

jamanetwork.com/journals/jam...

We (with @tspisak.bsky.social, @christianbuchel.bsky.social) published a commentary on Chowdhury, Bi et al. (2025, JAMA Neurology) raising serious concerns about their reported results.

👇 1/13

Boundary constraints can determine pattern emergence The robust patterning of cell fates during embryonic development requires precise coordination of signalling gradients within defined spatial constraints. Using a geometrically confined in vitro syste...

New work with Saunders & Charras labs

Physical boundaries guide cell fate decisions during human trunk development

Reaction Diffusion model shows how geometry shapes biology with TBXT expression forming consistent domains regardless of colony size & shape

www.biorxiv.org/content/10.1...

Finally out in PRX Life. Enjoy 😄 journals.aps.org/prxlife/abst...
Social Cohesion, residence time, and habitat-choice accuracy emerge as key metrics shaped by social interaction, revealing exploration-exploitation trade-offs in collective foraging of egalitarian groups. @cbehav.bsky.social

Boats on Kieler Förde

Do you like neuronal networks and maybe also programming? 🧮🕸️💻
I am looking for a research assistant to work on the general topic of neuronal network models, either theoretically or with a link to specific model organisms. Please see below for more details. ⬇️
#research #neuronalnetworks #kiel #cau

Top-down and bottom-up neuroscience: overcoming the clash of research cultures - Nature Reviews Neuroscience As scientists, we want solid answers, but we also want to answer questions that matter. Yet, the brain’s complexity forces trade-offs between these desiderata, bringing about two distinct research app...

Finally published:
“Top-down and bottom-up neuroscience: overcoming the clash of research cultures”
www.nature.com/articles/s41...

Looking for ways to better understand different neuroscientific perspectives and enable productive collaborations

The development of aperiodic neural activity in the human brain header

How is prefrontal neural activity refined as we age?

Out today in @nathumbehav.nature.com‬! This study, from Elizabeth Johnson, uncovers how subtle changes in neural 'noise' impact our attention, memory, and cognition through development.

Proud to have contributed!

www.nature.com/articles/s41...

Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model Overview of our approach for extreme value statistics. First, we fit a normative model to imaging phenotypes, before employing a ‘peaks-over-threshold’ approach widely used in meteorology and finance....

👀

Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
onlinelibrary.wiley.com/doi/full/10....

New 2 year position as an Imaging Data Infrastructure Specialist

Located a the Hunter Medical Research Institute (HMRI) & the University of Newcastle (UoN), in partnership with the National Imaging Facility (NIF),

Apply here: www.seek.com.au/job/85537666