Daren Fearon

Accelerating Drug Discovery With High‐Throughput Crystallographic Fragment Screening and Structural Enablement Crystallographic fragment screening has become highly efficient, overcoming previous challenges of low throughput and time consumption, due to advances in synchrotron technology and the establishment...

Folks can also read about our experiences in fragment screening and elaboration, which have helped shape the FFF pipeline, in our recent perspective: doi.org/10.1002/appl...

08.01.2025 11:59 — 👍 4    🔁 1    💬 0    📌 1

Acknowledgement slide for joint talk of Frank von Delft and Warren Thompson from Diamond of fragment based drug discovery with MX DUC rep Dave Briggs on stage

Summary of xchem from frank von delft and follow on work and the tools being developed to help users to develop these fragment hits into hits and accelerate the drug discovery pipeline ..lots of new tools including fragalysis, fragmentstein, car encapsulated as fas forward fragments or f^3 i guess

07.01.2025 15:42 — 👍 5    🔁 2    💬 1    📌 0