Salomé CARCY

Optimized detection and inference of immune cell type names in single-cell RNA sequencing data Abstract. Accurate identification of immune cell subsets in single-cell RNA sequencing (scRNA-seq) data is critical for understanding immune responses in a

Researchers developed optimized detection and inference of names in scRNA-seq data (scODIN) to enhance the understanding of immune cell heterogeneity and immune regulation. Read more to see the broad implications for immunology and personalized medicine: ow.ly/InOb50XS9k2.

And we're live, Lecture A1 is online. Introduction to Bayesian workflow, generative models, estimands, estimators, estimates, error checking, beginnings of probability theory and Bayesian updating. www.youtube.com/watch?v=ztbY...

Table titled "Guidance for Communicating With Patients About Medical Numbers". Columns: Recommendation, Potentially Problematic Communication, and Preferred Communication. Examples include using numbers to convey risk and providing context.

Clinicians can enhance patient understanding by using numerical data instead of verbal probabilities, consistent denominators, absolute risk comparisons, and clear context for unfamiliar data types.

ja.ma/3KW7LI0

Reaching maturity: Thymic γδ T cell differentiation in mice and humans γδ T cell differentiation into specialized effector subsets during both early life and adulthood is reviewed.

Reaching maturity: Thymic γδ T cell differentiation in mice and humans

#gdTcells

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Guidelines for T cell nomenclature - Nature Reviews Immunology This Consensus Statement clarifies the existing subset-based nomenclature for T cells. Furthermore, it proposes an alternative modular nomenclature that is designed to be brief and flexible and to avo...

..cross your 't's folks.. here's how!

www.nature.com/articles/s41...

J-2 congrès SFI 💛

Paris is remembering the victims of the November 13, 2015 attacks. To mark ten years since the terrorist attacks, the city is organizing a tribute at Place de la République. Starting November 8, people can come by to leave a candle or flower in memory of the victims.

Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold.

Want to get a tough sample, like lung, looking like this? Read more!

www.biorxiv.org/content/10.1...

Il y a 4 jours, le sénat -à moitié vide- a voté une modification du système de formation en médecine, qui est -selon moi - assez problématique :
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Have you considered submitting a paper to @jhumimmunity.org ?

To know more about us, please read our inaugural editorial: rupress.org/jhi/article/...

Med student paradise: two entire rows of highlighters

#medstudent
#medschool

Cancer immunotherapy by γδ T cells The premise of cancer immunotherapy is that cancers are specifically visible to an immune system tolerized to healthy self. The promise of cancer immunotherapy is that immune effector mechanisms and i...

γδ T cells are a unique population of immune cells that can recognize and kill tumors.

A 2024 #ScienceReview explores current research efforts focused on how γδ cells naturally discriminate cancers from healthy tissues. https://scim.ag/3L4i3oU #ScienceMagArchives

Yang, Farber and colleagues @columbiamed.bsky.social show how lung tissue resident memory T cells optimize protection through IL-10 production which regulates #macrophage-mediated #inflammation in the lungs. rupress.org/jem/article/...

#InnateImmunity #MucosalImmunology

CD2 and its ligands are involved in development and activation of #MAITcells, say Kaiwen Zhu, Yan Lu, André Veillette et al. @ircm.bsky.social rupress.org/jem/article/...

#InnateImmunity #LymphocyteBiology

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56e Congrès Annuel de la Société Française d'Immunologie
📅 12-14 novembre 2025
📍 Cité des Sciences et de l'Industrie, Paris

📢 Soumission des abstracts : 4 septembre 2025
💸 Tarifs réduits: 15 septembre
Tarifs préférentiels membres SFI lnkd.in/dujxvKki

🚀 Go ➡️ www.alphavisa.com/sfi/2025/fr/

The MAIT cell response to controlled oral enterotoxigenic E. coli challenge Abstract. Mucosal-associated invariant T (MAIT) cells recognize conserved microbial antigens presented by the non-polymorphic MR1 molecules and play import

Pleased to share our latest paper providing new insights regarding the human MAIT cell response to gastrointestinal bacterial infection (ETEC). @ki.se academic.oup.com/jimmunol/adv...

🚨 New review from @taghonlab.bsky.social: We summarise the current state of knowledge about the identity and molecular biology of human thymus seeding progenitors.
📖 Read it now in JACI: www.sciencedirect.com/science/arti...
@ugent-fge.bsky.social

Got new #TCR-pMHC data to send our way into BATCAVE? Wanna try BATMAN to predict targets of your #TCR? We would love to hear from you!

💽Database+codes: github.com/meyer-lab-cs...

💻BATMAN software + tutorials: github.com/meyer-lab-cs...

🦇Lets decode TCR-pMHC logic, one mutation at a time🦇

T cell receptor cross-reactivity prediction improved by a comprehensive mutational scan database Banerjee et al. present a comprehensive T cell receptor cross-reactivity database and a hierarchical Bayesian framework to predict T cell receptor targets. Together, they reveal structural and biochem...

Check out how we tackled one of the fundamental challenges in immunology, out today @cp-cellsystems.bsky.social: www.cell.com/cell-systems.... Our major innovations are BATCAVE and BATMAN, two new players to get us closer to solving TCR-pMHC predictions!

Ponction lombaire réussie ⇒ externe ramène un dessert ! 😇 Il y aura de la mousse au chocolat demain quelque part à @hopitalbretonneau.bsky.social 😋

Lumbar puncture success ⇒ med student must bring a dessert ! 😇 Chocolate mousse on the menu tomorrow @ Hôpital Bretonneau 😋

Human MAIT cell response profiles biased toward IL-17 or IL-10 are distinct effector states directed by the cytokine milieu | PNAS Mucosal-associated invariant T (MAIT) cells are unconventional T cells that mediate rapid antimicrobial immune responses to antigens derived from m...

Good evening Bluesky! This my first message in this forum:
Proud to share our latest findings out yesterday in @pnas.org showing how human mucosal-associated invariant T (#MAIT) cells rapidly adapt their functional response profile to cues in the microenvironment www.pnas.org/doi/10.1073/...
@ki.se

Beautiful peacock wandering around in the botanical garden in #Tours, just across the street from the lab…

It’s the end of a week at Christophe Paget’s lab @cepru1100.bsky.social It was so refreshing to think scientifically again, especially to have debates with Paget’s lab members! Can’t wait to come back whenever I have another week of med school vacation 😇

Back to geriatrics rotation on Monday 🩺

Beautiful peacock wandering around the botanical garden in #Tours, across the street from the lab…

Distinct type I and II interferon responses direct cortical and medullary thymic epithelial cell development Single-cell transcriptomics identifies type I and II interferons as regulators of cortical and medullary thymic epithelial differentiation.

In #Science #Immunology, researchers at @stanfordmedicine.bsky.social studied #IFNs in human #fetal #thymus development. They found type I & II IFNs play distinct but critical roles in cortical & medullary thymic #EpithelialCell differentiation!

The same lady sat down next to us at hospital and gave us a new origami 🥹

Source temps de travail moyen des internes: isni.fr/wp-content/u... (enquête 2023 menée auprès de 2277 internes)