In the absence of high quality evidence wouldn't it be better to encourage participation in REMAP-CAP and Recovery trials for influenza? Guidelines can be an obstacle to evidence generation.
Entitled imperialists with rose-tinted spectacles.
Remap-cap or Recovery. Randomise is better than random care.
I think the evidence for treatment is lacking and we should randomise to remap-cap or recovery rather than administering random care.
A joint call for action on sepsis from the ICS and BIA urges a simple but vital change in antibiotic administration to save lives.
Continuous infusions can reduce sepsis deaths in critical care. More on this update in the full statement: bit.ly/StatementSepsis
#IntensiveCare #SepsisAwareness
New:
Greater recovery after critical illness (GRACE): a call to action to create a new roadmap for critical illness research
thorax.bmj.com/content/earl...
Hopefully, not an insignificant ask.
There is another similar but different study nearing completion called Mega-ROX. This will hopefully give us a better signal for certain subgroups of patients.
#VisualAbstract A 7-day course of hydrocortisone in severe community-acquired pneumonia was unlikely to reduce 90-day mortality and may pose potential harm, despite a possible reduction in shock duration. zurl.co/Z9lKj
Conservative Oxygen Therapy With Mechanical Ventilation
jamanetwork.com/journals/jam...
Conservative oxygen therapy with a target SpO2 of 90% did not reduce 90-day all-cause mortality compared to usual oxygen therapy in mechanically ventilated adult patients.
#CCR25 @criticalcarereviews.com
https://ja.ma/4kG5gWK
Our @ICNARC CMP data shows our demographic is not very ethnically diverse. >97% white.
Today's Paper of the Day is:
Interhospital Transfer of Patients With Acute Pulmonary Embolism
https://criticalcarereviews.com/latest-evidence/paper-of-the-day
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
New report out today!
A review of the quality of rehabilitation care after an ICU admission: ncepod.org.uk/2025icur.html @Davido744 @BACCNUK @ICS_updates
@theRCOT @thecsp @BDA_Dietitians @rcgp
@RCSLT @FICMNews
@ICUsteps @UKCCNA
@RCoANews @GeriSoc @hqip.bsky.social
Heading over to #CCR25, hoping that my plane isn’t delayed and I also catch the ICC-CTN meeting tomorrow.
Editorial: Rapid sequence induction: a modern-day example of Theseus' Paradox?
Stept and Safar described ‘rapid induction/intubation’ in 1970.
PUMA recently issued a consensus statement on RSI.
Let's compare.
@sthjournalclub.bsky.social
#AnSky #AirwaySky
doi.org/10.1111/anae...
Hypernatremia of critical illness
CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch
Effect of Ventilator Mode on Ventilator-Free Days in Critically Ill Adults: A Randomized Clinical Trial
CCR Journal Watch - tracking the critical care literature daily
https://criticalcarereviews.com/latest-evidence/journal-watch
Please consider responding to this important survey following on from publication of the ADAPT-Sepsis trial
jamanetwork.com/journals/jam...
#IDsky #Medsky #ICUsky #Ansky 🧪
🚑 New Episode of Clinical Conversations🎙️
Pre-hospital sedation carries serious ethical and clinical risks. In this episode of Clinical Conversations, @expensivecare.bsky.social and I explore why it’s risky and how to make it safer.
#Paramedicine #PreHospitalCare #EmergencyMedicine #Sedation #EMS
Today's Paper of the Day is:
Use of Inotropic Agents in Advanced Heart Failure
https://criticalcarereviews.com/latest-evidence/paper-of-the-day
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
This video from NEJM Evidence explores the basis for non-inferiority trials, the meaning of non-inferiority margins, and the interpretation of a non-inferiority trial’s results.
Check out our Stats, STAT! playlist on YouTube to explore more statistical concepts: youtube.com/playlist?lis...
#MedSky
There may still be time for Northumbria to recruit to the MARCH trial, although I think they are hoping to complete recruitment fairly soon.
Managing Immune Checkpoint Inhibitor Pneumonitis in the ICU
CCR Journal Watch
criticalcarereviews.com/latest-evide...
Get the latest critical care literature every weekend via the CCR Newsletter - subscribe at criticalcarereviews.com/newsletters/...
Today's Paper of the Day is diagnosis and management of alcohol-associated hepatitis
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Today's Paper of the Day is acute kidney injury in patients with cirrhosis
criticalcarereviews.com/latest-evide...
Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025
Acute Onset of Impaired Consciousness
CCR Journal Watch
https://criticalcarereviews.com/latest-evidence/journal-watch
Get the latest critical care literature every weekend via the CCR Newsletter - subscribe at https://criticalcarereviews.com/newsletters/subscribe
It feels like the use of oseltamivir is strongly adhering to Brandolini's law.
