@ivlrose.bsky.social
Uses functional genomics to study astrocytes in neurodegenerative disease 🧪. Neuroscience PhD candidate at UCSF (Kampmann Lab). He/him 🏳️🌈
National Cancer Institute projection of a 4% pay line in FY2026.
Good grief, the US National Cancer Institute projects it will fund only one in 25 RO1 grant applications in 2026. This is massively defunding cancer research. Despicable vandalism. www.cancer.gov/grants-train...
24.07.2025 10:32 — 👍 304 🔁 153 💬 6 📌 19
Tenure-track faculty search of the UCSF Biochemistry & Biophysics Department is open for applications!
We are looking for creative, innovative scientists asking fundamental questions in any area of biology.
Join our vibrant, collaborative, and supportive community!
aprecruit.ucsf.edu/JPF05702
Astrocytes connect specific brain regions through plastic gap junctional networks https://www.biorxiv.org/content/10.1101/2025.07.18.665573v1
22.07.2025 19:15 — 👍 14 🔁 4 💬 1 📌 4
Pooled #CRISPR screens are a staple of functional genomics in mammalian cells. Yet somehow in the best genetic model™ no equivalent system was available. Until now! The @perrimonlab.bsky.social lab now presents efficient pooled CRISPR screening in #Drosophila cells.
www.nature.com/articles/s41...
Look at that lovely single layer of astrocytes on the retinal surface!
27.06.2025 12:48 — 👍 1 🔁 0 💬 1 📌 0Still the ggoat
11.06.2025 01:34 — 👍 36 🔁 6 💬 0 📌 0Maybe, idk. In previous labs I’ve used decades old ultracentrifuges and rotors without issue. This one just feels like a cash grab
07.06.2025 18:38 — 👍 1 🔁 0 💬 1 📌 0Exactly! It feels like pure extortion on the part of the company
07.06.2025 16:04 — 👍 0 🔁 0 💬 1 📌 0
Today I learned that ultracentrifuge rotors expire?? And need to be repurchased periodically? These things still feel brand new and should last decades...
06.06.2025 19:23 — 👍 1 🔁 0 💬 1 📌 0
The side of a box of Parafilm that features the flask, dish, and beaker. Text has been added under them. The flask is labelled chemistry, the dish biology, and the beaker jam making. Jam making is written in a different handwritten font
At times like these it's important to remember the 3 branches of science
26.05.2025 22:04 — 👍 76 🔁 22 💬 3 📌 1
"to run a contest that you end up not funding as a private organization at this time is… both extremely wasteful of these people’s time, and just devastating in terms of morale."
I spoke with @aniloza.bsky.social at STAT today about HHMI's decision not to fund this round of Hanna Gray applicants.
A graphical abstract for the linked paper. It depicts an adorable calico cat on a pink background. There are two caption bubbles pointing to the cat: one black and the other orange. These two bubbles respectively contain depictions of the ARHGAP36 gene in both orange and black/brown fur expression.
The mutation responsible for orange coloration in domestic cats has been identified! This effect in ARHGAP36, an X-linked gene, explains why male cats are more likely to be orange. 🧪
www.cell.com/current-biol...
It’s quite the dance!
15.05.2025 04:21 — 👍 1 🔁 0 💬 0 📌 0My ongoing request:
If your NSF or NIH grant was terminated--whether at Harvard or elsewhere--please report it here.
NSF: grant-watch.us/submit-nsf.h...
NIH: grant-watch.us/submit-nih.h...
Our trackers are actively used in lawsuits and are often the only record that terminations ever occurred.
P.S. - 51 weeks a year this is a science account, but for one glorious week we're talking Eurovision!
14.05.2025 02:48 — 👍 2 🔁 0 💬 1 📌 0
Not sure how it made it through the Semifinal 1, but I'm so glad it did! #Eurovision www.youtube.com/watch?v=5MS_...
14.05.2025 02:47 — 👍 1 🔁 0 💬 1 📌 0Thrilled to announce that my lab is now open at Ohio State! We study astrocytes as gene therapy targets for brain repair after ischemic stroke and in vascular dementia, developing new viral tools along the way. If you're interesting in joining or collaborating, please reach out!
gleichmanlab.com
🧬The interactive RNA sequencing resource from the Daneman Lab is now live!🧬
Built by Ben Gastfriend, this user-friendly tool lets you explore gene expression changes across multiple conditions!
Check it out here: danemanlab.shinyapps.io/bbbtranscrip...
Summer Research Program in Neuroscience & Computation For undergrads interested in exploring the brain and learning how to code No prior experience necessary! June - August 2025 UCSF Mission Bay campus 25-30 hours/week commitment Learn more & apply: http://tiny.cc/ucsfcompneuro/ Students from backgrounds historically underrepresented in STEM are encouraged to apply!
New opportunity for Bay Area undergrads to gain computational neuroscience exposure and training!
I’m teaming up with @neuronush.bsky.social to offer this to students in our communities 💕🧠🧪
Please share with any students who might be interested!
Tiny.cc/ucsfcompneuro
Huge opportunity for postdocs gearing up for an academic job search, hosted by @stanford-chemh.bsky.social @berkeleymcb.bsky.social and UCSF!
25.04.2025 23:46 — 👍 51 🔁 34 💬 0 📌 0They’re beautiful!
16.04.2025 15:26 — 👍 1 🔁 0 💬 1 📌 0New preprint evaluating the recent claim of epigenetically regulated immune memory in astrocytes.
We believe this finding was likely artifactual, resulting from immune cell contamination & cell type mis-annotation across multiple transcriptomics experiments:
I saw a cell that looked just like him! Let me find it…
04.04.2025 03:22 — 👍 0 🔁 0 💬 1 📌 0
Immunocytochemistry micrograph showing cells appearing to make little faces. Some are aghast and some are just chilling with little sunglasses.
All the little cells are making faces at me
03.04.2025 22:35 — 👍 3 🔁 0 💬 1 📌 0
Congratulations Dr. @parkergrosjean.bsky.social! 🎓🎉🎉🎉
Thank you for your contributions to the Kampmann lab & UCSF - combining AI/ML with functional genomics to uncover regulators of neuronal activity.
We are missing you already - but excited for your next adventures at @insitro.bsky.social!
Real consequences to Trump.
Dr. Marc Ruel, one of the world's top heart surgeons, was set to move from Ottawa to San Francisco this year.
He backed out because of the political situation here and the mistreatment of Canada by Trump through tariffs and annexation
www.kqed.org/news/1203279...
I’m surprised to hear that these might be one continuous cell instead of two twin cells. I’ve seen instances where I transduced one with an AAV but not the other
21.03.2025 19:05 — 👍 2 🔁 0 💬 0 📌 0
