Tony Bruns (Bruns Lab Aachen)'s Avatar

Tony Bruns (Bruns Lab Aachen)

@brunslab.bsky.social

Liver Disease Research. Our primary objective is to improve patient care focussing on the gut-liver axis in cirrhosis, peritoneal immunity & spontaneous bacterial peritonitis, acute-on-chronic liver failure, and cirrhosis-related immune dysfunction.

556 Followers  |  497 Following  |  1 Posts  |  Joined: 24.12.2023  |  1.5456

Latest posts by brunslab.bsky.social on Bluesky

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At the beautiful European mucosal immunology group conference #emig in Aachen ready for two days of great #mucosalimmunology sciences #interferosky #gastrosky 🧪

21.07.2025 07:57 — 👍 8    🔁 1    💬 0    📌 0
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🔥 We’ve hit 50% recruitment in the #COMBATtrial!
Huge thanks to all involved!💙
@rautoupe.bsky.social @hopitalbeaujon.bsky.social @hospitalclinic.bsky.social @rwth.bsky.social @uni-muenster.de @brunslab.bsky.social @medblab.bsky.social @frankuschner.bsky.social

#LiverSky #ClinicalTrial

30.06.2025 15:57 — 👍 2    🔁 2    💬 0    📌 0
a woman wearing glasses and a red jacket

a woman wearing glasses and a red jacket

Check out this electric insight from our Rising Star 2025, Carolin Schneider!
⭐ UEG Rising Star Awards are annually given to 10 of the most promising, emerging scientists. 🏆
🏆 Access Carolin's publication: https://bit.ly/3DDKzdX
#myUEGcommunity

12.05.2025 09:00 — 👍 4    🔁 1    💬 0    📌 0
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💉 Albumin duration & AKI response in cirrhosis
Eva M. Schleicher (Mainz) – #EASL2025
🕒 24h albumin new rule questioned
🏆 EASL AKI response definition wins
📈 20% of 24h NR improved at 48h
⚖️ Early vs late responders: Same mortality
🚨 Cr ↑ >16% @24h → terlipressin!
👇

09.05.2025 15:01 — 👍 4    🔁 2    💬 1    📌 0
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Back in the Abstract Session: Theresa Wirtz presents her scRNA-seq work on monocyte subsets and ACLF risk.

@rwth.bsky.social
@brunslab.bsky.social
@easlnews.bsky.social

#Cirrhosis #ACLF #EASL2025"

10.05.2025 08:58 — 👍 9    🔁 5    💬 0    📌 0
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🦠The recovery failure of fecal microbiota diversity in patients after liver transplant is associated with a complicated postoperative course

#POSTER SAT-518 by @beccsipollsi.bsky.social from @rwth.bsky.social at #EASL2025

@brunslab.bsky.social
@easlnews.bsky.social

10.05.2025 10:35 — 👍 13    🔁 4    💬 1    📌 0
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Congrats on presenting your poster in the Track Hub 4 this afternoon, @beccsipollsi.bsky.social ! 🙌

09.05.2025 14:45 — 👍 9    🔁 4    💬 0    📌 0
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Next at the DECISION Networking Session at #EASL2025, Theresa Wirtz (UKA) presents scRNA-seq data showing a monocyte subset linked to ACLF risk.
Fascinating translational science in action!
@brunslab.bsky.social ky.social @easlnews.bsky.social ky.social

#scRNAseq #ACLF

09.05.2025 08:09 — 👍 11    🔁 7    💬 0    📌 0
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Global epidemiology of acute kidney injury in hospitalised patients with decompensated cirrhosis: the International Club of Ascites GLOBAL AKI prospective, multicentre, cohort study This study found important regional differences in AKI severity, phenotype, management, and outcomes in patients with decompensated cirrhosis. Health-care coverage remains an important driver of survi...

📣 ICA GLOBAL AKI study published in @lancetgastrohep.bsky.social

🗺️3,821 patients with cirrhosis
✅38% had AKI
⚠️discrepancies in AKI management and outcomes
⚠️ AKI ➡️22.9% 28-day mortality

🎯Need for equitable & standardized care

www.thelancet.com/journals/lan...

11.03.2025 15:52 — 👍 9    🔁 7    💬 2    📌 0
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The non-canonical inflammasome activators Caspase-4 and Caspase-5 are differentially regulated durin... The non-canonical inflammasome, which includes caspase-11 in mice and caspase-4 and caspase-5 in humans, is upregulated during inflammatory processes and activated in response to bacterial infections ...

Immunology research on bacterial infections in patients with cirrhosis: The human inflammatory caspases 4 and 5 are differentially regulated in patients with immune dysfunction due to sepsis and In acute-on-chronic liver failure. www.frontiersin.org/articles/10....

24.12.2023 20:04 — 👍 9    🔁 1    💬 0    📌 0

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