Our lab is seeking candidates to apply for a 3-year postdoctoral fellowship in the area of plant synthetic biology funded by the Spanish Research Council. Deadline for applications is 17 Dec. Please, spread the word! contact: k.wabnik@upm.es

Wow cool! COngratz Ari!

Fig. 4.Model of auxin de-repression. When the auxin concentration in the nucleus is low (A), the effect of ARFas, as well as other non-ARF transcription factors, is limited by Aux/IAA-mediated recruitment of the TPL co-repressor, closing the locus. As auxin levels rise (B), AFBs ubiquitinate Aux/IAAs, thereby allowing all transcription factors to act on the locus. As a result, there is a significant difference in gene expression between baseline and auxin induction. In afb1,2,3,4 mutants (C), Aux/IAAs are not degraded, and therefore the promoter remains closed. In the iaa2mDII degron mutant (D), one of three Aux/IAAs is stabilized, thereby resulting in only partial promoter closure. In arfasept lines, Aux/IAAs are not recruited to the promoter. While gene expression remains diminished without activating ARFs, other non-ARF transcription factors are allowed to provide baseline gene expression. However, there is no auxin-mediated induction.

🌱📖 RESEARCH 🌱📖

Bascom et al. used CRIPSR/Cas9 to produce a septuple AUXIN RESPONSE FACTOR mutant in the model bryophyte Physcomitrium patens , revealing the developmental consequences of the complete loss of auxin-mediated gene activation 🌱📖

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪

Fig. 1 (shortened, full legend in paper): Auxin responses and auxin-adjacent transcription factors (TFs) control developmental transitions in bryophyte gametophytes. (A) Wild-type (WT) auxin responses (left) cycling between low and high auxin. Under low auxin, A-ARFs are kept in a repressive complex by AUX/IAAs via recruitment of the TOPLESS co-repressor and associated histone deacetylases (HDACs). Under high auxin, auxin mediates the interaction between TIR1/AFB and AUX/IAAs, leading to AUX/IAA ubiquitination and proteolysis. A-ARFs are then free to interact with SWI/SNF ATPases and histone acetylases (HACs), leading to open chromatin states. Positive (TIR1/AFB, A-ARF, SWI/SNF, HAC), negative (AUX/IAA, TPL, HDAC) and auxin-adjacent (TFs) factors are shown. Auxin is represented by an A.

🌱🧬 INSIGHT 🧬🌱

Complete loss of A-ARF activity in bryophytes reveals a role for auxin-adjacent regulatory networks – Flores-Sandoval & Bowman comment on an original research article by Bascom et al.

📝 Insight: doi.org/10.1093/jxb/...

🔬 Research: doi.org/10.1093/jxb/...

#PlantScience 🧪

ERAD machinery controls the conditional turnover of PIN-LIKES in plants Plant ERAD machinery governs the turnover of auxin transporters involved in developmental and stress responses.

Thrilled to share our latest story on the ERAD machinery and how it controls the conditional turnover of PIN-LIKES for acclimative growth

www.science.org/doi/10.1126/...

🌱 #SeminarSeriesCBGP is back! 🎙️

Join us Sept 2025–Jan 2026 for top voices in plant science at CBGP

📍 CBGP Auditorium + Zoom
🕛 12:30 PM
🔗 Speakers & calendar: shorturl.at/Atsyn
📎 Full schedule w/ Zoom links: shorturl.at/yT3e6

Don’t miss it! 👩‍🔬👨‍🔬

Stem cell regulators drive a G1 duration gradient during plant root development - Nature Plants A positional and developmentally regulated cell cycle duration gradient exists in the root meristem whereby the G1 phase is very long close to the stem cell niche. This relies on the interplay of PLET...

Did you know that there is a cell cycle duration gradient in plant root meristem? New story by joining forces between Plant dynamics lab and Crisanto Gutiérrez & Bénédicte Desvoyes lab @cbgpmadrid.bsky.social @cbm-csic-uam.bsky.social #Plants #roots #cellcycle www.nature.com/articles/s41...

#PaperCBGP

🌱🔬 Plant cell walls are more than physical barriers. They are dynamic shields!

A CBGP review published in @jxbotany.bsky.social explores how cell walls shape plant defense against pests, paving the way for more sustainable farming strategies ♻️🌍

📎 More: shorturl.at/GLNYL

#ICAR2025

Check out our lab posters: P125 and P88 #ICAR25 #PlantScience @cbgpmadrid.bsky.social To learn about New 4D modeling simulators and auxin-dependent root growth!!

Join the PlantDynamics to develop next-gen 4D organ simulators The @PlantDynamics Laboratory  (https://pdlab.es) is seeking a motivated and talented

PlantDynamics is recruiting a programmer to join efforts in developing plant (and other) organ simulators
euraxess.ec.europa.eu/jobs/341946
Contact me directly if you are interested: k.wabniK@upm.es

The Camelot paper is now published. If you ever wanted to try biomechanics, Camelot is an inexpensive and easy way to get started. @matmajda.bsky.social

t.co/x3l0lllNS2

We have a new Doctor form the #pollmannlab in town 👨🏻‍🎓Congratulations to Adrián to his wonderful PhD defense 🎉 Outstanding job. Also a great shoutout to the panel for the critical assessment of the work. We will surely pick up some of the points.
@cbgpmadrid.bsky.social @etsiaabupm.bsky.social @upm.es

Our editors write:

- Cell polarity: Unequal signalling and biosynthesis in daughter cells rdcu.be/egIl5

de nada!

Research Briefing by @routierlab.bsky.social and @sysilveira.bsky.social about our recent paper @natureplants.bsky.social

Mechanical interactions between tissue layers underlie plant morphogenesis Nature Plants - Anthers, the male reproductive organs in plants, are a model to explore the establishment of complex three-dimensional shapes. Live imaging, genetics and modelling reveal an active...

Do you want to know how mechanical interaction between tissue layers controls the formation of complex organ shapes in plants? 🔬🌼
🚨Our latest collaborative work with @routierlab.bsky.social is now published @natureplants.bsky.social
Find out more👉 rdcu.be/efad3

Fantastic collaboration! and exciting findings! congratz to all involved!

🌱💡 Computational modeling and genetic experiments confirm that this asymmetry optimizes root growth, ensuring robust meristem function. @wabniklab.bsky.social

Time-lapse imaging back then, Zeiss scope from 1950. #microscopy #timelapse #imaging

Thx!

Using computer modeling and quantitative analysis of plant transcriptomes, we show how common design principles in core clock control photoperiod-dependent florigen function in short-day vs long-day plants #clock #circadianclock #oscillators #flowering #plantgrowth

Regulatory principles of photoperiod-driven clock function in plants The circadian clock provides a fundamental timing mechanism for plant fitting to seasonal changes in the photoperiod. Although photoperiodic regulatio…

Our take on Photoperiod regulation of core clock across plants:
www.sciencedirect.com/science/arti...

very neat! Congratulations!

and @ataly.bsky.social @bic-bordeaux.bsky.social
First authors Jessica Perez-Sancho, Marija Smokvarska , Gweenogan Dubois .

Our lab is looking for a enthusiastic researcher with the master degree (Computational Biology, Computer Science, Game development) to develop next-gen computer games to model organ development in 4D. If you are interested drop me an email: k.wabnik@upm.es

#SeminarCBGP | 07/02/25 - 12:30h

🧑🏽‍🔬 Dr. Robertas Ursache
🌍 Centro de Investigación en Agrigenómica (CRAG)
Barcelona, Spain
📝 "The suberinterestingrole of GELP proteins”
💻 Zoom ID: 867 7606 8944 | Código acceso: 189185

#somosUPM