PSL-Qlife

Qrieux, la série - Episode 6 - ADN sous tension : condition essentielle à sa réparation Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

Voici notre 6ème épisode de Qrieux, la série:
ADN sous tension : condition essentielle à sa réparation
Avec Chantal Prévost, Afra Sabei et Mara Prentiss (IBPC), Paris, France.
Qrieuz, la série met en valeur les recherches des scientifiques de @pslqlife.bsky.social.
#scicomm

ouvaton.link/Azp8fQ

Check-out this episode and all the others of the "Qrieux" series to discover research developed @psl-univ.bsky.social university in Paris! @pslqlife.bsky.social @ca-fait-science.bsky.social
#sciencedissemination

www.youtube.com/playlist?lis...

Qrieux, la série - Épisode 5 - Mieux dormir grâce aux astrocytes Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

Nous sommes ravis de vous présenter l'épisode 5 de Qrieux, la série:
Mieux dormir grâce aux astrocytes
Avec @rancillac.bsky.social , Félix Bellier et Leana Razaghi
En français avec sous-titres français et anglais
ouvaton.link/9TlIHj

#Neuroscience #Qrieux
@psl-univ.bsky.social @pslqlife.bsky.social

🚨 Qlife members — don’t miss this rare chance!
Join the Physical Biology of the Cell course by Rob Phillips!

📅 Sept 29–Oct 3, 2025
📍 Marseille
➡️ Deadline: August 20

🔗 More info: centuri-livingsystems.org/centuri-trai...

#QuantitativeBiology #course

📣 Demain, Qlife débarque au @doublesciencefest.bsky.social !

🎬 Au programme : diffusion de #Qrieux_La_Serie, notre série de vulgarisation scientifique en collab avec @ca-fait-science.bsky.social

➡️ À (re)découvrir aussi sur YouTube : youtube.com/@psl-qlife91...

🔴 Demandez le programme ! À quelques jours du festival, découvrez celui de @institutcurie.bsky.social

🪧 Plus d'infos sur : www.festivaldoublescience.fr

Créé par l’AP-HP, Gustave Roussy et l’Institut Curie, labellisé par l’Institut national du cancer, Paris Kids Cancer rassemble des équipes franciliennes de recherche et de soin, des universités et associations de parents pour accélérer l’innovation thérapeutique en oncologie pédiatrique.

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🎙️ Mieux comprendre le développement et la maturation du système immunitaire pour mieux soigner les cancers de l’enfant : ce fut le thème principal du 1er symposium international du centre de recherche en oncologie pédiatrique Paris Kids Cancer (PKC), qui a eu lieu les 5 et 6 juin 2025.

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Une présentation des deux dernières vidéos réalisées par @ca-fait-science.bsky.social aura lieu. Suivies d'un échange avec les chercheurs ayant participé à ces deux épisodes. @pslqlife.bsky.social @drawinscience.bsky.social
#Qrieux_La_Serie

Mechanical strengthening of cell-cell adhesion during mouse embryo compaction Compaction is the first morphogenetic movement of the eutherian mammals and involves a developmentally regulated adhesion process. Previous studies investigated cellular and mechanical aspects of comp...

Congrats to the @maitrejl.bsky.social lab! 👏 Ludmilla de Plater, Julie Firmin
@institutcurie.bsky.social
www.cell.com/biophysj/ful...

Electroluminescence and energy transfer mediated by hyperbolic polaritons - PubMed Under high electrical current, some materials can emit electromagnetic radiation beyond incandescence. This phenomenon, referred to as electroluminescence, leads to the efficient emission of visible p...

Congrats for the collab between the @yannickdewilde.bsky.social lab & @lpens-phys.bsky.social ! 👏 Abou-Hamdan*, Schmitt*, Bretel, Rossetti, Tharrault, Mele, Pierret, Rosticher, Berroir, Fève, Ménard, Plaçais, Voisin
@espciparispsl.bsky.social @lpens-phys.bsky.social
pubmed.ncbi.nlm.nih.gov/40108465/

Pervasive formation of double-stranded RNAs by overlapping sense/antisense transcripts in budding yeast mitosis and meiosis - PubMed Previous RNA profiling studies revealed coexpression of overlapping sense/antisense (s/a) transcripts in pro- and eukaryotic organisms. Functional analyses in yeast have shown that certain s/a mRNA/mR...

Congrats to the Morillon lab! 👏 Ugo Szachnowski, Maxime Wery
@institutcurie.bsky.social
pubmed.ncbi.nlm.nih.gov/39848697/

A tunable and versatile chemogenetic near-infrared fluorescent reporter Near-infrared (NIR) fluorescent reporters open interesting perspectives for multiplexed imaging with higher contrast and depth using less toxic light. Here, we propose nirFAST, a small (14 kDa) chemog...

Congrats for the collab between the labs of Perez, Morin, Gautier! 👏 @linaelhajji.bsky.social B Bunel, O Joliot , C Li, @agtebo.bsky.social C Rampon, M Volovitch, E Fischer, N Pietrancosta
@normalesup.bsky.social @ibensens.bsky.social @institutcurie.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...

Decoupling shear stress and pressure effects in the biomechanics of autosomal dominant polycystic kidney disease using a perfused kidney-on-chip Kidney tubular cells are submitted to two distinct mechanical forces generated by the urine flow: shear stress and hydrostatic pressure. In addition, …

Congrats to the Descroix lab! 👏 Brice Lapin, Jessica Vandensteen, Giacomo Gropplero, Sylvie Coscoy
@institutcurie.bsky.social
www.sciencedirect.com/science/arti...

Breast tumors from ATM pathogenic variant carriers display a specific genome-wide DNA methylation profile - Breast Cancer Research Background The ataxia-telangiectasia mutated (ATM) kinase phosphorylates and activates several downstream targets that are essential for DNA damage repair, cell cycle inhibition and apoptosis. Germlin...

Congrats to the labs of Lesueur & Salomon! 👏 N Viart, AL Renault, S Eon-Marchais, Y Jiao, L Fuhrmann, S Murat El Houdigui, D Le Gal, E Cavaciuti, MG Dondon, J Beauvallet, V Raynal, D Stoppa-Lyonnet
@institutcurie.bsky.social
breast-cancer-research.biomedcentral.com/articles/10....

Pennate diatoms make non-photochemical quenching as simple as possible but not simpler Studies of marine microalgal photosynthesis are heavily moulded on legacy research from organisms like Arabidopsis and Chlamydomonas, despite the differences between primary and secondary endosymbiont...

Congrats to the Bailleul lab! 👏 Dany Croteau, Marianne Jaubert, @afalciat.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...

MMnc: multi-modal interpretable representation for non-coding RNA classification and class annotation As the biological roles and disease implications of non-coding RNAs continue to emerge, the need to thoroughly characterize previously unexplored non-coding RNAs becomes increasingly urgent. These mol...

Congrats to the Radvanyi lab! 👏 Constance Creux
@institutcurie.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...

Combining Two Mechanistically Distinct Reactions from a Single Iron Complex: A Tandem Approach to Thermally Stable and Recyclable Polymers An iron-based catalytic system can act as an efficient and selective tandem catalyst for the production of poly(silylether)s, followed by the ring-opening polymerization of lactide, providing direct ...

Congrats to the lab of @thomaspolymer.bsky.social ! 👏 Kanokon Upitak
@chimieparistechpsl.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...

Parasitic plasmids are anchored to inactive regions of eukaryotic chromosomes through a nucleosome signal | The EMBO Journal imageimageThe naturally occurring S. cerevisiae 2µ plasmid is one of few documented cases of eukaryotic plasmids, undergoing equal distribution between mother and daughter cells during mitosis. Using ...

Congrats between the lab of @rkoszul.bsky.social and the @ajafa.bsky.social lab! 👏 F Girard, A Even, A Thierry, M Ruault, @leameneu.bsky.social P Larrous, M Garnier, S Adiba, A Cournac
@pasteur.fr @institutcurie.bsky.social @ibensens.bsky.social
www.embopress.org/doi/full/10....

Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors Musiani et al. demonstrated that in the absence of UNG, uracil excision by SMUG1 induces replication stress, evidenced by its impact on replication fork progression, accumulation of single-strand brea...

Congrats for the collab between the Ceccaldi lab and the Fachinetti lab! 👏 D Musiani, H Yücel, M Vallette, A Angrisani, R El Botty, B Ouine, N Schintu, C Adams, M Chevalier, D Heloise, A El Marjou, E Marangoni
@institutcurie.bsky.social
www.cell.com/molecular-ce...

Kinetic Redox Shotgun Proteomics Reveals Specific Lipopolysaccharide Effects on Intestinal Epithelial Cells, Mitigated by a Mn Superoxide Dismutase Mimic Proteomics and redoxomics are efficient to quantify the effects of bacterial lipopolysaccharide in intestinal epithelial cells (HT29) at the proteome and at the Cys-redoxome levels. Oxidative stress ....

Congrats for the collab between the Policar lab and the Vinh lab! 👏 M Zoumpoulaki, G Chiappetta, J Bouvet, NR John, G Schanne, P Gehan, @sdiebolt.bsky.social S Shakir, E Quévrain, E Mathieu, N Delsuc
@chimieens.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...

Adaptable Range-Separated Hybrids for the Description of Excited States: Tuning the Range Separation Parameter on Effective Charge Transfer Distance - PubMed In this contribution, we describe a novel approach, rooted in the time-dependent density functional theory, enabling to adapt range-separated hybrids (RSHs) to correctly describe excited states (ESs) ...

Congrats to the I-CLeHS lab! 👏 Tianhong Yan, Alessandro Bonardi, Carlo Adamo, Ilaria Ciofini
@chimieparistechpsl.bsky.social
pubmed.ncbi.nlm.nih.gov/39936364/

Growth factor-triggered de-sialylation controls glycolipid-lectin-driven endocytosis - PubMed Glycolipid-lectin-driven endocytosis controls the formation of clathrin-independent carriers and the internalization of various cargos such as β1 integrin. Whether this process is regulated in a dynam...

Congrats to the Johannes lab! 👏 E MacDonald, @aforrester.bsky.social @cessvala.bsky.social E Dransart, A Akhil Shp, L Leconte, V Chambon, D Ghosh, A Pinet, D Bhatia, B Lombard, D Loew, MShafaq-Zadah, @christianwunder.bsky.social
@institutcurie.bsky.social
pubmed.ncbi.nlm.nih.gov/39984654/

Negative global-scale association between genetic diversity and speciation rates in mammals Genetic diversity is critical for species evolution and their adaptability to global changes, while speciation rate is critical for explaining large-scale patterns of species richness. Exploring corre...

Congrats to the Morlon lab! 👏 @acafonsosilva.bsky.social Odile Maliet, @leandrist.bsky.social
@ibensens.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...

A single microfluidic device for multi-omics analysis sample preparation - PubMed Combining different "omics" approaches, such as genomics and proteomics, is necessary to generate a detailed and complete insight into microbiome comprehension. Proper sample collection and processing and accurate analytical methods are crucial in generating reliable data. We previously developed th …

Congrats to the Vinh lab! 👏 Ranjith Kumar, Iman Haddad, Massamba Ndiaye, @mmarbout.bsky.social @marathon-yann.bsky.social
@espciparispsl.bsky.social @pasteur.fr
pubmed.ncbi.nlm.nih.gov/39820672/

Unravelling single-cell DNA replication timing dynamics using machine learning reveals heterogeneity in cancer progression Genomic heterogeneity has largely been overlooked in single-cell replication timing (scRT) studies. Here, we develop MnM, an efficient machine learning-based tool that allows disentangling scRT profil...

Congrats to the Chen lab! 👏 Joseph Josephides
@institutcurie.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...

Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus - PubMed In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...

Congrats @rkoszul.bsky.social & @ajafa.bsky.social labs! 👏 @leameneu.bsky.social * @christophechapard.bsky.social * J Serizay*, M Ruault, @mnn9171.bsky.social F Girard, A Bignaud, A Even, @aurelepiazza.bsky.social A Thierry
@pasteur.fr @institutcurie.bsky.social
pubmed.ncbi.nlm.nih.gov/39913590/

📣 Publication thread of the month 📰
👇🏼 Check out the great publications of the Qlife members!
#february #march
@psl-univ.bsky.social

@agencerecherche.bsky.social

La campagne #UneJonquilleContreleCancer s’est achevée, mais le combat contre le #cancer continue ! 🎯

Merci infiniment à toutes celles et ceux qui se sont mobilisés aux côtés de l’Institut Curie tout au long du mois de mars. Ensemble, nous avons fait fleurir l'espoir contre le cancer 🙏🌼

Awesome week at the @pslqlife.bsky.social spring school in Paris! Jam packed with fantastic speakers and workshops exploring quantitative methods in dev bio.

All made even better by many pastries, glorious weather and a great cohort