We are beyond excited about this new MSc in Pain Neurosciences programme!! π§βππ©βπ come join our buzzing Oxford pain community!!
29.09.2025 13:06 β π 3 π 0 π¬ 0 π 0@anninaschmid.bsky.social
Professor of Pain Neurosciences at Oxford University and Physio at heart:-)
We are beyond excited about this new MSc in Pain Neurosciences programme!! π§βππ©βπ come join our buzzing Oxford pain community!!
29.09.2025 13:06 β π 3 π 0 π¬ 0 π 0Thanks for having us Mark, always nice to share science! Have a look at this if you are interested in whiplash associated disorder and our recent evidence for nerve pathology and neuropathic pain in some: youtu.be/yip3I689cwU
31.03.2025 10:00 β π 0 π 1 π¬ 1 π 1Thanks Ted, I will forward this to my collaboratorsπ₯³
07.03.2025 07:25 β π 1 π 0 π¬ 0 π 0Cool that these are helpful to you, I will watch out for your publications then!!
06.03.2025 12:11 β π 1 π 0 π¬ 1 π 0We have an opportunity for a funded PhD studentship on 'Illness perceptions and outcomes in people living with gout'. See: www.keele.ac.uk/study/postgr... #KeeleMSK
05.03.2025 11:33 β π 3 π 2 π¬ 0 π 0and most importantly, a massive thank you to all participants who made this study possible. thank you for your generous time commitment and patience!
@ndcnoxford.bsky.social
@ox.ac.uk
A massive thank you again to all co-authors, particularly
Joel Fundaun, Colette Ridehalgh and Andrew Dilley.
Particular thanks to our generous funders
@versusarthritis.bsky.social @medresfdn.bsky.social
Overall, our results present a complex phenotypic profile for people with WADII and provide evidence suggestive of peripheral neuroinflammation in a subgroup of individuals.
05.03.2025 20:47 β π 2 π 0 π¬ 1 π 0Several serum pro-inflammatory cytokines were raised in people with WADII. So inflammation can be detected systemically. x.com/AnninaBSchmi...
05.03.2025 20:47 β π 3 π 0 π¬ 1 π 0Magnetic resonance imaging T2 signal ratio was increased in the C5 root of the brachial plexus and the C5-C8 dorsal root ganglia in WADII participants compared with healthy controls. We did not find changes in the distal median nerve trunk.
05.03.2025 20:47 β π 1 π 0 π¬ 1 π 0In the other publication published in
@painthejournal.bsky.social, we focussed on the presence of neuroinflammation in these patients using MRI, serum cytokine evaluation as well as other measures.
journals.lww.com/pain/fulltex...
Multivariable linear regression suggested low-cost bedside tests for hypoaesthesia at the index finger were prognostic for whiplash-related upper quadrant pain 6-months post-injury, however this association was weak.
05.03.2025 20:47 β π 1 π 0 π¬ 1 π 0We also took skin biopsies. Intraepidermal nerve fibre densities at the index finger were not significantly different between groups. However, dermal myelinated nerve bundles at the index finger were reduced 6-months post-injury in participants with WADII compared to controls.
05.03.2025 20:47 β π 1 π 0 π¬ 1 π 0Intriguingly, these functional changes were accompanied by elevated serum neurofilament light chain levels (a marker for axonal damage) acutely after whiplash. This normalised 6 months later. This suggests there is actual structural damage to axons in some people with WADII.
05.03.2025 20:47 β π 1 π 0 π¬ 1 π 0QST demonstrated significantly reduced thermal and mechanical detection thresholds in acute WADII compared to controls, some of which persisted at 6 months.
05.03.2025 20:47 β π 1 π 0 π¬ 1 π 0Within 4 weeks of injury, 65% of people with WADII had neuropathic pain which persisted in 32% 6-months post-injury.
05.03.2025 20:47 β π 2 π 1 π¬ 1 π 1In this @brain1878.bsky.social publication, we demonstrate that people with WADII (traditionally not considered to involve nerve injury) have signs of functional and structural nerve pathology.
academic.oup.com/brain/advanc...
What an exciting week: two papers published in
@brain1878.bsky.social and @painthejournal.bsky.social on the findings from our whiplash cohort. Massive thank you Joel Fundaun, Colette Ridehalgh, Andrew Dilley and other co-authors who were instrumental in making this happen. Short summary below.
Do you have a basic science background and are interested in doing a PhD at Oxford University? Fully funded UK studentship available for 2025 intake to study the role of B-cells in human neuropathic pain
To apply please see here:
www.ndcn.ox.ac.uk/study-with-u...
Haha, welcome online Falko! Great to meet you!!!
08.02.2025 13:16 β π 1 π 0 π¬ 1 π 0Agree, super cool!!!
11.12.2024 08:24 β π 1 π 0 π¬ 0 π 0Thank you!!!
04.12.2024 21:36 β π 0 π 0 π¬ 0 π 0Wonderful, thank you!!! Still finding my way here π
04.12.2024 21:36 β π 1 π 0 π¬ 0 π 0