David Oriola

🧩 Day 5! Agent-based modeling took center stage today with Alexandria Volkening 🐟🌀

From swarming to zebrafish stripes, participants explored how cells self-organize.

✨ Flash talks & a keynote by Katie Bentley wrapped up the day! #EMBOMulticellModeling

🧠 Day 4 was all about 🧬 noise in biology — from master equations to stochastic simulations, led by Jordi Garcia-Ojalvo!

🔬 Group projects continued, and the day ended with a fascinating keynote by @jamesbriscoe.bsky.social on morphogen mediated tissue patterning! #EMBOMulticellModeling

🧬 Day 3! From spatial models and Turing patterns to the interplay of gradients and self-organisation, today was packed with insights and hands-on work.

Participants also began their group projects and wrapped up the day with an inspiring keynote by @bertaverd.bsky.social! #EMBOMulticellModelling 💡🧠

🧪 Day 2 of the EMBO Practical Course at the Collaboratorium!
From solving ODEs in Python to applying them to gene regulatory networks and diving into object-oriented programming with VEDO. #EMBOMulticellModelling 💻🧬

🔬 Day 1 of the EMBO Practical Course on Computational Modelling of Multicellular Systems kicks off at the Collaboratorium!

Participants were welcomed by @jamesasharpe.bsky.social, setting the stage for a week of exploring how computational tools help us understand tissue and organ dynamics. 💻🧬

Amazing defense by @alisonkickuth.bsky.social! Congratulations on the beautiful thesis!

After its renewal last week, our Excellence Cluster Physics of Life will be taking on new challenges! In the upcoming weeks, we will be explaining here our new scientific directions, represented by 7 interwoven Research Avenues🔬👩‍🔬
Stay tuned!

Learn more: tud.link/5f2m72

#biophysics #research #dfg

50+% cut to the US National Science Foundation budget is staggering. These include cuts for research in Chemistry. Physics, Geology, Math, Engineering, Computer Science.

Scientific discoveries and training of our next generation of scientists and engineers are halved.

How is that helping the US?

Nucleoli as biomolecular bubble tea! Congrats to former Princeton ugrad Holly Cheng (now GS @MIT) ->Holly's senior thesis work, a close collab w Roggeveen Wang & @zs-biophys.bsky.social‬ &Stone. Come for the cool movies & stay for the viscoelasticity! www.pnas.org/doi/10.1073/pnas.2407423122

This could be one of the coolest meetings of the year!!

Why biotech is booming in Barcelona World-class research institutes and university hospitals, a culture of groundbreaking science and a thriving investment ecosystem make Barcelona a rising star in the life sciences industry, as these t...

www.nature.com/articles/d42...

Flocking and active solid behavior of epithelial cells in our new study in @pnas.org
Great work of Y. Shen, J. O'Byrne and
@andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez!
| PNAS www.pnas.org/doi/10.1073/...

How does metabolism drive early development in the embryo? Well done to @jesseveenvliet.bsky.social
(a PoL Associate) and all involved in new groundbreaking publications released in Cell Stem Cell. Read all about it below!

Learn more in the press release here: tud.link/dndnvh

Congratulations Laura Avinyo! @lauavinyo.bsky.social and Heura Cardona! First paper of your PhD 🎉. doi.org/10.1242/dev.... Beautiful quantified trajectory of how the skeletal pattern of the gene Sox9 emerges during limb development. @embl.org @barcelonacollaboratorium.com

Reconstructing gene expression patterns gives mouse studies a leg up

Read this Research Highlight showcasing work from Laura Aviñó-Esteban @lauavinyo.bsky.social, Heura Cardona-Blaya & James Sharpe @jamesasharpe.bsky.social:

journals.biologists.com/dev/article/...

Extending a warm welcome to Bluesky for the @barcelonacollaboratorium.com, our joint initiative with @embl.org Barcelona.

🚀 Ready to be inspired? Check out our Fellows' and Alumni Starter Pack! 💡✨ Dive into their groundbreaking work and join us on this journey of discovery. 🌍🔬

Follow us to explore more! 🌟 👉 go.bsky.app/DTMWAHX

PhD positions available at the intersection of theoretical physics & biology (contact: m.c.ucar@sheffield.ac.uk )

📣 I’m looking for PhD students to work at the intersection of theoretical physics & biology -topics range from active cell mechanics to collective cell migration & tissue patterning!

Feel free to reach out for more info (DM/email)!

Please repost / share 🙂

Cell-cell communication controls the timing of gastruloid symmetry-breaking In the embryo, morphogenetic signals instruct regional patterning thereby defining the body axes of the future animal. Remarkably, in the absence of such signals, collections of pluripotent stem cells...

And because it really is Christmas, another study by @davidoriola.bsky.social and @viktri08.bsky.social lab showing how cell-cell communication can drive the timing of symmetry breaking!
www.biorxiv.org/content/10.1...

Special thanks to the EMBL Barcelona family for a fantastic time there. Best place to do science by the beach!

Cell-cell communication controls the timing of gastruloid symmetry-breaking In the embryo, morphogenetic signals instruct regional patterning thereby defining the body axes of the future animal. Remarkably, in the absence of such signals, collections of pluripotent stem cells...

Really happy to share with you my last work from my time in @embl.org with the @viktri08.bsky.social group. We studied the dynamics of cell fate transition in gastruloids and found that cells communicate with each other to control the timing of symmetry breaking. www.biorxiv.org/content/10.1...

Arrested Coalescence: A Tool to Explore Tissue Rheology Tissue spheroids are self-organised 3D cellular aggregates that serve as a versatile platform in tissue engineering. While numerous high-throughput methods exist to characterise the cellular function ...

My first post in @bsky.app! Happy to share the first contribution from my group on how the phenomenon of arrested coalescence can be used to explore tissue rheology www.mdpi.com/2673-4125/4/.... A review on the methods, theory and simulations of tissue fusion. Hope you enjoy it!

My first post on @bsky.app. So happy to announce that our work has been published in Development by @biologists.bsky.social
doi.org/10.1242/dev....

Also a big thanks for "The people behind the papers" article as well! doi.org/10.1242/dev....