Barral Lab

'In February 2024, in response to an independent review of research bureaucracy, the Department for Science, Innovation and Technology urged UKRI to consider alternative options on the collection of research impact data, “including no longer using Researchfish, from 2025 onwards”.' 1/3

UKRI renews contract with Researchfish - Research Professional News Science department had previously urged funder to consider alternative options on impact tracking

UKRI renews contract with Researchfish, despite the government last year urging the funder to consider alternatives to the impact-tracking service.

www.researchprofessionalnews.com/rr-news-uk-r...

Congratulations! 🥂 🎉

Falling vaccination rates leave millions of children at risk, experts warn More than 30m children worldwide not fully immunised for MMR and UK ranks worst in G7, WHO and Unicef say

“Vaccines save lives, and when coverage drops, disease spreads.” Dr Hans Kluge, the WHO regional director for Europe.
• invest in strong local health systems
• ensure vaccines are available to all
• fight misinformation

www.theguardian.com/world/2025/j...

Enhorabuena Jose y team! 🍾 🎉 Really cool work

Spagnoli Lab. One Walk Please help us raise vital funds for Breakthrough T1D, the leading global type 1 diabetes (T1D) research charity. Your support will help change the lives of everyone affected with T1D - Thanks so much...

We are doing it again!! 🚶‍♀️🚶‍♂️🚶🧪🧫🔬
For the Second Year My Lab is participating to the
One_Walk_London 🎡 to raise money for life-changing research & make a difference to T1D #diabetes
⤵️
support.breakthrought1d.org.uk/fundraisers/...

Please help us raise funds for @breakthrought1duk.bsky.social

Our third webinar from the AUS/APAC region, will feature Nick Gherardin and Sho Yamasaki. Thursday, June 12th at 17:00 AEST (8:00 London, 16:00 Tokyo).

If you'd like to keep up to date, sign up to the mailing list here: cd1mr1.com/cd1-mr1-soci...

All 4 of my NIH research grants are terminated. These were grants on MDR-TB treatment & strategies for supporting adolescents living w/ HIV. This is a massive waste of resources. I am heartbroken for my Harvard team, my partners in Peru, the next generation of scientists & our country. Shame.

Is the UK paying the price for world’s most expensive visas? | The Observer Competing political and economic goals on immigration are resulting in the loss of valuable skills and talent in the UK

“The visa fees are so exceedingly high that it makes coming here very difficult for some people. We are fishing for the best scientists in the world. They want to come and work here because we are such an effective country at science, but if we have these high costs, they can and will go elsewhere.”

Top cancer experts ‘being put off UK by politicians’ messaging on immigration’ Exclusive: Leaked report says high visa costs also derailing clinical trials and research, denying NHS life-saving drugs

#InTheNews: Beating cancer requires top scientists, but our latest global policy report has found that political discourse and high visa costs are deterring experts from working in the UK.
Read more in @theguardian.com 👇

Every 10 seconds vaccination saves a life. Immunization for all is Humanly Possible

It’s #WorldImmunizationWeek

Vaccines have saved 154 million lives in the last 50 years. That’s 6 lives every minute.

A reminder of what is #HumanlyPossible. Science saves lives.

#VaccinesWork
bit.ly/wiw2025

Academia is cool because if you're doing it right, every paper you published in the last 3 years feels inadequate now that you understand the topic better, but it'll take 3 years to get out the version where you get it more right, and you get to do that until one day you die! Isn't that cool

We are witnessing the destruction of science in America | Paul Darren Bieniasz If we stay on this administration’s course, future life-saving medicines may never be invented

"Science in the US is entering a phase resembling the Lysenko era in the Soviet Union."
www.theguardian.com/commentisfre...

We are witnessing the destruction of science in America | Paul Darren Bieniasz If we stay on this administration’s course, future life-saving medicines may never be invented

This is a hard read from Paul Bieniasz, the tragedy is that the end of this nightmare doesn't seem anywhere close.

www.theguardian.com/commentisfre...

Gender equality doesn’t just 'happen.'

Women’s rights must be fought for and protected.

Our responsibility is clear.

To lead by example and create a world where opportunities are fair for all.

Not just today, but every single day.

#InternationalWomensDay

The first measles death in the US in a decade -- the tragic, preventable death of a child whose parents chose not to protect them with vaccination -- should spark an immediate nation-wide campaign to ensure all children are protected against preventable diseases. Anything less is unconscionable.

Adaptive immunity in barrier tissues Immune responses lie at the heart of almost every aspect of human health, including host responses to infection, autoimmunity, cancer, metabolism and aging. While adaptive immune responses by B and T…

🦠🔬 We are very excited to organize an EMBO workshop on Immunity in Barrier Tissues with Carolyn King! @immunologyking.bsky.social

📍 Where: Basel, Switzerland
📅 When: 26th–29th August 2025
📝 Registration deadline: 30th May 2025

Check out the program and details 🔗

#EMBOBarrierTissues @embo.org

I believe that science is real and essential, love is love, black lives matter, feminism is for everyone, transgenic mice are cool, and immigrants are welcome.

Say it with me... 🧪 👩‍🔬

A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer Acha-Sagredo et al. stratify colorectal cancers using features of an immune-reactive tumor microenvironment. This microenvironment, locally abundant in cytotoxic lymphocytes and antigen-presenting mac...

‘A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer’

www.cell.com/cancer-cell/...

A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer Acha-Sagredo et al. stratify colorectal cancers using features of an immune-reactive tumor microenvironment. This microenvironment, locally abundant in cytotoxic lymphocytes and antigen-presenting mac...

#WeekendRead. #InterferonPower. Ciccarelli &co show @cp-cancercell.bsky.social that an #interferon signature in macrophages & T cells during #colorectal #cancer leading to CD74 upregulation identifies patients responding to immune checkpoint inhibition therapy. #ScienceSavesLives dlvr.it/THwNgQ

a black and white cartoon of mickey mouse reading a book about how to kill . ALT: a black and white cartoon of mickey mouse reading a book about how to kill .

What shall one do when a referee has not read half of your paper and rejects it asking for results that are already done and perfectly described in the submitted file?

Review: MAIT cell homing to the gut in health and disease provides insights to guide therapeutic development for intestinal inflammation
science.org/doi/10.1126/...

Congrats Mauro and Apurwa. Great work!

Congratulations Apurwa Trivedi for your PhD defense on MAIT cell dynamics in lymphatics. First one from the lab 😃. Thanks to @barrallab.bsky.social, Helena Paidassi and Frank Garland for evaluating the work.

Vaccination against hepatitis B can help prevent liver cancer in children, against human papillomavirus (HPV) in young girls can help prevent cervical cancer later in life.

Today is #WorldCancerDay

Did you know❓

Vaccination against #hepatitisB can help prevent liver cancer in children, while #HPV vaccination for young girls can reduce the risk of #CervicalCancer later in life.

Learn more 👉bit.ly/2NeFF8B

Pink square graphic with black text which reads, 'World Cancer Day - 4 February'

In the UK, nearly 1 in 2 people will get cancer in their lifetime. It's World Cancer Day today – a global day to raise awareness and take action against cancer 🌍

Whatever your cancer experience, share this post and help us get the word out.

#WorldCancerDay #WCD2025

A black and white photo of two young boys. One is covered in the tell-tale pustules of smallpox while the other boy is not. This photo is courtesy of the Dr. Jenner House Museum.

Photo of two boys - one vaccinated against smallpox, the other not - published in 1901 by Dr. Allan Warner.

Smallpox killed over half a billion people in the 20th century alone. On 8 May 1980, the WHO announced its eradication, which was achieved through #vaccines, surveillance, and containment.

This is the front page of a fraudulent research article that purported to show a link between vaccines and autism. The word "RETRACTED" is written across it in large red letters. Wikipedia: On 28th February 1998, a fraudulent research paper by physician Andrew Wakefield and twelve coauthors, titled "Ileal-Lymphoid-Nodular Hyperplasia, Non-Specific Colitis, and Pervasive Developmental Disorder in Children", was published in the British medical journal The Lancet.[1] The paper falsely claimed causative links between the measles, mumps, and rubella (MMR) vaccine and colitis and between colitis and autism. The fraud involved data selection, data manipulation, and two undisclosed conflicts of interest.

Today is Retraction Day, when we observe the anniversary of the retraction (Feb. 2, 2010) of the fraudulent paper that purported to show a link between vaccines and autism. 🧪#medsky

Our second webinar hosted from USA, will be by Laurent Gapin and Antonia Rotolo.
Thursday, February 6th at 16:00 GMT (8:00 Pacific, 11:00 Eastern, 1:00 Friday Tokyo)

If you haven't join, get updates and link here: www.cd1mr1.com/cd1-mr1-soci...

Vaccines do not cause autism.

Keep saying things that have been demonstrated by robust science and are the subject or organised disinformation. Don’t just ignore the attempts to brainwash.

#academicsky