It will be hard to keep up with this excellent start ππ»πͺ
18.07.2025 20:06 β π 1 π 0 π¬ 0 π 0@mikaelpalner.bsky.social
Researcher: The biological cause of mental illnesses, the pharmacological and neurobiological effects of treatments, including psychedelic drugs in both high and microdoses. All posts are my own view and not a medical advice.
It will be hard to keep up with this excellent start ππ»πͺ
18.07.2025 20:06 β π 1 π 0 π¬ 0 π 0Chairs and vice chairs for the Psychedelics GRC
We worked so well as a team for the #GRCPsychedelics @vyazovskiy.bsky.social @viditavaidya.bsky.social @melissaherman.bsky.social
and congrats to @theborislab.bsky.social and @mikaelpalner.bsky.social, who will be the future vice-chairs!
Climbing with fellow scientists at Psychedelics GRC
Science together climb together - sneaked out with fellow #GRCPsychedelics attendees for a quick session πͺ
16.07.2025 23:37 β π 31 π 7 π¬ 0 π 0As i recall we also discussed this in our chat right?
I agree completely.
But great to see a study in patients.
One more clip from my interview with @mikaelpalner.bsky.social.
In this one, he outlines a neurological definition for a psychedelic "microdose" according to binding occupancy at the serotonin receptor.
And, of course, what that means.
youtu.be/gG3JmDo_liU
Microdosing research is being polluted by a lack of specificity, says Dr. @mikaelpalner.bsky.social
youtu.be/0MZy1eLQUxY
I love my new office hallway mates, DEI πͺ
24.02.2025 13:32 β π 2 π 0 π¬ 0 π 0@mikaelpalner.bsky.social and I debate the value of removing the psychedelic effect from psychedelic drugs.
youtu.be/Qokk8MGkeHY
"The very fact that I am having to publish this anonymously in a country that has the right to free speech written into our Constitution is an indictment of what is happening."
www.bmj.com/content/388/...
Links to your favorite podcast provider, from YouTube to Spotify right here -> www.jameswjesso.com/microdosing-...
17.02.2025 20:35 β π 0 π 0 π¬ 0 π 0Visited @jameswjesso.bsky.social **Adventures Through The Mind** podcast to talk about microdosing, psilocybin and translation of psychedelic science from rats to humans.
#microdosing #psilocybin
I talk with Dr. Mikael Palner from Southern Denmark University about his research on the effects of chronic low dose (microdose) psilocybin on stress resiliency and compulsive behaviours.
www.jameswjesso.com/microdosing-...
#psychedelics #microdosing #psychedelicscience
Send me an email mpalner@health.sdu.dk
I am in the us at a conference but my lab is in Copenhagen Denmark.
Really feeling the #wcbr, if you are around join us for the panel on micodosing tomorrow afternoon.
New research will be presented ππ»
@lizs1.bsky.social I'm happy to comment, I did a scientific study above on microdosing psilocybin in rat. www.nature.com/articles/s41...
27.01.2025 00:46 β π 6 π 1 π¬ 1 π 0+1 π
25.01.2025 03:56 β π 1 π 0 π¬ 0 π 0With president Trump hitting hard on science in the US, I want to let all my fellow US researchers know that Danish foundation provides quite a lot of postdoctoral and sabattical funding for visiting US citizens.
Reach out if you want to know more or collaborate while this goes down.
Here are my thoughts -> www.nature.com/articles/s41...
20.01.2025 19:30 β π 5 π 1 π¬ 0 π 0Link to Davids commentary: psychiatryonline.org/doi/10.1176/...
12.01.2025 16:36 β π 0 π 0 π¬ 0 π 0SV2A imaging in the living rat brain using the tracer 18F-SynVest-1
Are you thinking of measuring synaptic plasticity in the living rat brain? Maybe after psychedelic-induced neuroplasticity, as David E Olson suggests in his recent commentary in the American Journal of Psychiatry
Check out our SV2A images using [18F]SynVest-1
#psychedelic #neuroplasticity #invivo
This is a great review of novel measurements of functional connectivity.
But how would you explain "structurally informed functional connectivity" to a lay person?
Give me your best shot π
www.nature.com/articles/s41...
A #ScienceReview from last year highlights the growing recognition of the complex cognitive capacities of #rats and its implications for how they are treated in scientific contexts.
01.01.2025 15:07 β π 55 π 13 π¬ 1 π 1Reach out to these people, would love to hear more about this study: jamanetwork.com/journals/jam...
20.12.2024 17:43 β π 2 π 0 π¬ 1 π 0Thanks, this is actually a semi awake approach. Where 18F-FDG is taken up while the animal is awake and freely moving in their home cage. Then sedated and we take a snapshot of the accumulated activity.
But anyways I would love to hear about your awake head fixation as well. After new years π
We didn't look at the visual cortex in this study, we had two prespecified circuits. But we will make the data available to anybody.
16.12.2024 17:21 β π 0 π 0 π¬ 0 π 0Yes we hear the same, now we know they are. Also in terms of long-term connectivity changes.
16.12.2024 05:26 β π 2 π 0 π¬ 1 π 0Try flowers πΊ
15.12.2024 21:23 β π 0 π 0 π¬ 0 π 0Full preprint here: osf.io/preprints/os...
15.12.2024 20:58 β π 3 π 1 π¬ 1 π 0