Umberto Perron

What Peterborough doing? 😅

17-year-long Scottish study of 82,000+ adults finds commuting by bike reduces your risk of:
• early death
• hospitalisation for any reason
• cardiovascular disease
• cancer mortality
• treatment for mental health problems.

Yeah, but those LTNs and bike lanes are *really* annoying.

YouTube video by Nicole van der Hoeven Actually getting things done with Obsidian // Checklist plugin

Definitely doesn't have all the bells and whistles but checklist + Daily notes works well for me youtu.be/ODhHTngIMJE?...

Three must read papers for PhD students. #scisky #PhD #science #research #academicsky

1. The importance of stupidity in scientific research

Open Access
journals.biologists.com/jcs/article/...

Immunotherapy for oncology
New more effective & cheap anti-venoms
Allosteric switch proteins
New Alzheimer’s treatments
De novo functional nanopores
Vaccines
And so much more from Baker Lab. Thank you for being such an inspiration and for forging a path forward. 🚀💜

www.youtube.com/live/HnT1VWz...

possibly the only good docker

We updated our BindCraft preprint with lots of new exciting results! We release all our binder sequences and models, include more in silico analysis, novel design targets, and present AAV retargeting to specific cell types using de novo binders!
www.biorxiv.org/content/10.1...

Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science.

www.biorxiv.org/content/10.1...

Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪

Strong new evidence for T cell exhaustion in myalgic encephalomyelitis (ME/CFS) reflecting chronic viral infection, relevant to #LongCovid, and possible path to treatment candidates
www.pnas.org/doi/epub/10.... @pnas.org

#ExperimentRequest does anyone have room in their budget to A) retrain MPNN exclusively on cold-adapted proteins and B) express some designs and measure their thermostability?

edible antifreeze? yum 🧊

btw that staircase isn't Midjourney hallucinating, it's actually a real place @embl.org 🧬

so sick!

as long as it doesn't shrug

Now I can share external links without the posts being down regulated - I thought it would share this again!:)

I have compiled a list of now 100+ companies in the 'TechBio' space into a fully open database for the community.

Find here and please share if you like
open.substack.com/pub/harrisbi...

The sky is blue over the south building @ebi.embl.org 💙

Ah yes, aka the limma syndrome. (I jest ofc, limma is great)

A cartoon robot using a chainsaw on a log

There’s a new Practical Cheminformatics post, “Some Thoughts on Dataset Splitting,” (with code and a robot cartoon) at practicalcheminformatics.blogspot.com/2024/11/some... .

The assumption of normality

The classics are back

aha nice! I wonder if I could combine it with a summary prompt and then use it to create a bot? You could even add a classifier to get the relevant ones 🤔 oh well, into the weekend project pile it goes never to re-emerge

yes, I think the summary output looks very familiar if you've ever played with lit summary prompts. So the secret sauce must be a human in the loop selecting papers from a list of hits? Sounds suspiciously like drug discovery

Or build something similar? @amelie-iska.bsky.social @ddelalamo.bsky.social

Any chance of getting Biology+AI Daily in here? Biggest X pull factor left for me tbh

Great stuff! Can't wait to try this out (yay MIT) 🤓

or vs something like TCRmodel2?

who knew it would be easier to get everyone to switch social media platforms than getting them to use hg38

Know as the "not so South building " now I guess? 😎

Woah, on the other side of the road?