Cardiovascular Research Cluster (CVRC)

Electrosurgical Laceration and Stabilization of Clip Followed by Transapical Mitral Valve Replacement after Failed Transcatheter Edge-to-Edge Mitral Valve Repair: A Promising Alternative to Surgery - ... Surgical intervention in patients with failed edge-to-edge mitral valve repair carries a high risk of complications. The ELASTA-clip technique, combined with transapical mitral valve replacement, offe...

New publication: Electrosurgical Laceration and Stabilization of Clip Followed by Transapical Mitral Valve Replacement after Failed Transcatheter Edge-to-Edge Mitral Valve Repair: A Promising Alternative to Surgery. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40742024/
#CVRCBern

Beneficial APD-shortening effects, but deleterious negative inotropism of IKs-activator Docosahexaenoyl glycine (DHA-gly) in long QT syndrome type 2 - PubMed DHA-gly-induced IKs enhancement shows promising results in shortening APD/QT in LQT2 rabbits, while having no effect on LQT1 (impaired IKs). However, its adverse effect on cardiac contractility, even ...

New publication: Beneficial APD-shortening effects, but deleterious negative inotropism of IKs-activator Docosahexaenoyl glycine (DHA-gly) in long QT syndrome type 2. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40794559/
#CVRCBern

Influence of pericyte-like vessel dilation on RBC flux in an In Vitro microvascular network - PubMed Efficient oxygen delivery in the brain relies on a finely tuned balance between vascular architecture and dynamic flow regulation. While red blood cells (RBCs) passively flow through the capillary net...

New publication: Influence of pericyte-like vessel dilation on RBC flux in an In Vitro microvascular network. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40769421/
#CVRCBern

Das war die Nacht der Forschung 2025 Rund 10’000 Besucherinnen und Besucher tauchten in die Nacht der Forschung ein – und begegneten Hunderten Forscherinnen und Forschern der Universität Bern. Impressionen von einem bunten Fest des…

Am 06.09.2025 fand die Nacht der Forschung an der #unibern statt. Rund 10‘000 Besuchende folgten der Einladung. Wir haben einige Highlights zusammengefasst: www.uniaktuell.unibe.ch/2025/das_war...

#ndfunibern

Rocker or pump? Transcriptomic response of endothelial cells exposed to peristaltic pump-based unidirectional flow vs. rocker-induced bidirectional flow - PubMed Rocking-platform perfusion systems rely on hydrostatic pressure differences to perfuse cells in organ-on-chip devices. These systems are popular due to their tubing-free design, which facilitates para...

New publication: Rocker or pump? Transcriptomic response of endothelial cells exposed to peristaltic pump-based unidirectional flow vs. rocker-induced bidirectional flow. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40746301/
#CVRCBern

Protocol of the exploratory prospective observational PEAK study: PrEcision medicine in the management of cardiovascular surgery associated Acute Kidney Injury (AKI) - PubMed NCT06471621.

New publication: Protocol of the exploratory prospective observational PEAK study: PrEcision medicine in the management of cardiovascular surgery associated Acute Kidney Injury (AKI). Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40744512/
#CVRCBern

Vascular Graft and Endograft Infections: A Delphi Consensus Document on Terminology, Definitions, Treatment, Outcomes, Follow Up, and Reporting Standards - PubMed Consensus was achieved for 29 statements, which were developed to establish a common perception of VGEI and secondary aorto-enteric erosion/fistula, with the potential to improve research in this fiel...

New publication: Vascular Graft and Endograft Infections: A Delphi Consensus Document on Terminology, Definitions, Treatment, Outcomes, Follow Up, and Reporting Standards. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40744353/
#CVRCBern

The Cardiovascular Research Cluster (CVRC), will also present a variety of research and activities. You can find us at UniS, floor -1, room A-119 and hallway

Saturday, September 6 at 16:00h
#CVRCBern

Join us today! Celebrating the 10th Anniversary of the CVRC!

Current and future precision therapy approaches in the long QT syndrome - PubMed The long QT syndrome is a genetic arrhythmia disorder that predisposes patients to ventricular arrhythmias and sudden cardiac death. Pronounced genotype-specific differences in molecular mechanisms, a...

New publication: Current and future precision therapy approaches in the long QT syndrome. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40687888/
#CVRCBern

Multimodal Imaging Evaluation of Myocardial Involvement in Rare Oculoleptomeningeal Hereditary Transthyretin Amyloidosis - PubMed Early diagnosis and risk stratification in patients with vATTR are challenging. Cardiologists need an increased awareness because they may encounter patients with seemingly rare vATTR, such as the p.I...

New publication: Multimodal Imaging Evaluation of Myocardial Involvement in Rare Oculoleptomeningeal Hereditary Transthyretin Amyloidosis. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40681261/
#CVRCBern

Colchicine in patients with aortic stenosis undergoing transcatheter aortic valve replacement: a double-blind randomized trial - PubMed An inflammatory process may increase the risk of arrhythmias after transcatheter aortic valve replacement (TAVR). In this single-centre, double-blind, placebo-controlled, randomized trial we investiga...

New publication: Colchicine in patients with aortic stenosis undergoing transcatheter aortic valve replacement: a double-blind randomized trial. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40659682/
#CVRCBern

Anti-TRPV2 Autoantibody Linked to Sudden Infant Death Syndrome - PubMed Anti-TRPV2 Autoantibody Linked to Sudden Infant Death Syndrome

New publication: Anti-TRPV2 Autoantibody Linked to Sudden Infant Death Syndrome. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40623072/
#CVRCBern

We are at the big festival of knowledge and research!🩻🌠
Experience the full spectrum of our research firsthand with exciting attractions for all ages. 👉For an overview: www.medizin.unibe.ch/forschung/me... @unibe.ch @dbmr-unibe.bsky.social @cvrcbern.bsky.social @mcid-unibe.bsky.social

3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation: Results From the SWISS-APERO Randomized Clinical Trial - PubMed At 3 years after LAAC, there was no significant difference in the ischemic risk between the Amulet and the Watchman FLX groups. The lower occurrence of the ischemic composite endpoint observed in the ...

New publication: 3-Year Clinical Outcomes Comparing the Amulet vs Watchman FLX for Left Atrial Appendage Closure in Patients With Atrial Fibrillation: Results From the SWISS-APERO Randomized Clinical Trial. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40602941/
#CVRCBern

Effect of multimodal home-based prehabilitation on objectively measured physical activity in patients undergoing elective cardiac or non-cardiac major surgery: secondary outcomes from a randomised con... ClinicalTrials.gov Identifier: NCT04461301.

New publication: Effect of multimodal home-based prehabilitation on objectively measured physical activity in patients undergoing elective cardiac or non-cardiac major surgery: secondary outcomes from a randomised controlled trial. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40615882/

Wissenschaft erleben auf der Grossen Schanze! Forschung für alle, drinnen & draussen. 🗓️ Samstag, 6.9.25 ab 16 Uhr. 👉 https://unibe.ch/ndf #ndfunibern Wie heisst das hier 🍫?

An der Nacht der Forschung zeigen wir, wie vielfältig Sprache sein kann!
Kommen Sie vorbei – Eintritt frei!
📍 6. September 2025, ab 16 Uhr, Grosse Schanze Bern
www.youtube.com/watch?v=gHFn...
#ndfunibern

Uncovering hidden enhancers through unbiased in vivo testing - PubMed Chromatin signatures are widely used to identify tissue-specific in vivo enhancers, but their sensitivity and specificity remains unclear. Here we show that many developmental enhancers remain undetec...

New publication: Uncovering hidden enhancers through unbiased in vivo testing. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40775209/
@mosterwalder.bsky.social #CVRCBern

Management of the aortic arch in patients with syndromic heritable thoracic aortic disease - PubMed Concomitant prophylactic TAR in MFS patients undergoing elective root repair is not justified. One out of four MFS patients with history of AAD will have to undergo secondary TAR during follow-up. MFS...

New publication: Management of the aortic arch in patients with syndromic heritable thoracic aortic disease. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40581620/
#CVRCBern

In vitro renal artery stenting using a steerable guide wire navigated by a mobile electromagnetic field - PubMed Precise control of a steerable guide wire using a mobile external electromagnetic field is technically feasible in a three-dimensional silicone model of the human aorta. It facilitates <i>in vitro</i>...

New publication: In vitro renal artery stenting using a steerable guide wire navigated by a mobile electromagnetic field. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40661791/
#CVRCBern

Wissenschaft erleben auf der Grossen Schanze! Forschung für alle, drinnen & draussen. 🗓️ Samstag, 6.9.25 ab 16 Uhr. 👉 https://unibe.ch/ndf #ndfunibern Gold auf der Grossen Schanze? #ndfunibern

Finden wir Gold auf der Grossen Schanze? Finden Sie es heraus 👉 youtu.be/fNrbVeYL6Cs.
Wollen auch Sie mehr über Ihren Boden erfahren? Dann lassen Sie ihn kostenlos an der Nacht der Forschung analysieren – einfach eine handvoll mitbringen!
📍 Am 06.09., ab 16 Uhr, Grosse Schanze Bern #ndfunibern

📢 Swiss Physiology Meeting 2025 - last days to register!
📍 Bern, Sept 2
🎤 Keynotes: eating/metabolism & pain plasticity
🧠 Talks by young scientists + posters
📅 Poster deadline to compete for prize: Aug 3
👉 Info: www.ls2.ch/physiology2025
#Physiology #PhD #postdoc #posters

🌟 Postdocs – want to become a PI?
Apply for PIs of Tomorrow 2026 at the LS2 Annual Meeting (Feb 11–12, Zurich).
Prizes, feedback, and networking: annual-meeting.ls2.ch/2026/special...
Deadline: 5 Oct 2025
🔗 form.jotform.com/211792813615...
#Career #PIsOfTomorrow #Postdoc

Alcohol embolization versus non-invasive treatment for pain relief in peripheral venous malformations: a comparative study - PubMed Non-invasive treatment helps patients with venous malformations to manage maximal pain effectively. Alcohol embolization results in a faster and more pronounced reduction in mean and minimal pain leve...

New publication: Alcohol embolization versus non-invasive treatment for pain relief in peripheral venous malformations: a comparative study. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40656781/
#CVRCBern

Pickering syndrome facilitated by seronegative immune mediated necrotizing myopathy: a case report - PubMed Here, we describe a new case of acute congestive heart failure facilitated by severe reno-vascular hypertension in a patient with seronegative IMNM. This case highlights the importance of early recogn...

New publication: Pickering syndrome facilitated by seronegative immune mediated necrotizing myopathy: a case report. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40671720/
#CVRCBern

Post-doctoral position alert!

PhD position alert!

Call for Ambizione

Ambizione grants are aimed at early-career researchers who wish to conduct and lead a project of their own. Interested in learning more about this call? Take part in our online info event on 14 August 2025.

Submission deadline: 4 November 2025

➡️ buff.ly/dDQl9QA

Clinical and health status after permanent pacemaker implantation in patients undergoing transcatheter aortic valve replacement: Insights from the SCOPE I randomized trial - PubMed In the SCOPE I trial, new PPM implantation complicating TAVR had no impact on an integrated endpoint of vital and disease-specific health status throughout 3 years of follow-up.

New publication: Clinical and health status after permanent pacemaker implantation in patients undergoing transcatheter aortic valve replacement: Insights from the SCOPE I randomized trial. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40592695/
#CVRCBern

Comparison of 4D flow MRI and computational fluid dynamics in carotid models with different stenosis levels - PubMed Internal carotid artery (ICA) stenoses are a major source of stroke. In addition to traditional cardiovascular risk factors, hemodynamic parameters such as wall shear stress (WSS) are recognized as cr...

New publication: Comparison of 4D flow MRI and computational fluid dynamics in carotid models with different stenosis levels. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40499370/
#CVRCBern