Cardiovascular Research Cluster (CVRC)

Pickering syndrome facilitated by seronegative immune mediated necrotizing myopathy: a case report - PubMed Here, we describe a new case of acute congestive heart failure facilitated by severe reno-vascular hypertension in a patient with seronegative IMNM. This case highlights the importance of early recogn...

New publication: Pickering syndrome facilitated by seronegative immune mediated necrotizing myopathy: a case report. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40671720/
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Post-doctoral position alert!

PhD position alert!

Call for Ambizione

Ambizione grants are aimed at early-career researchers who wish to conduct and lead a project of their own. Interested in learning more about this call? Take part in our online info event on 14 August 2025.

Submission deadline: 4 November 2025

➡️ buff.ly/dDQl9QA

Clinical and health status after permanent pacemaker implantation in patients undergoing transcatheter aortic valve replacement: Insights from the SCOPE I randomized trial - PubMed In the SCOPE I trial, new PPM implantation complicating TAVR had no impact on an integrated endpoint of vital and disease-specific health status throughout 3 years of follow-up.

New publication: Clinical and health status after permanent pacemaker implantation in patients undergoing transcatheter aortic valve replacement: Insights from the SCOPE I randomized trial. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40592695/
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Comparison of 4D flow MRI and computational fluid dynamics in carotid models with different stenosis levels - PubMed Internal carotid artery (ICA) stenoses are a major source of stroke. In addition to traditional cardiovascular risk factors, hemodynamic parameters such as wall shear stress (WSS) are recognized as cr...

New publication: Comparison of 4D flow MRI and computational fluid dynamics in carotid models with different stenosis levels. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40499370/
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Redo minimally invasive LAA closure with WATCHMAN device - PubMed This video tutorial demonstrates the minimally invasive closure of a left atrial appendage (LAA) using the WATCHMAN device in a patient with a prior history of heart surgery. Given the failure of anti...

New publication: Redo minimally invasive LAA closure with WATCHMAN device. Congratulations to the authors!
pubmed.ncbi.nlm.nih.gov/40553011/
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WithScientists ist die Expert:innendatenbank der Kommission für Nachwuchsförderung der SCNAT. Lehrpersonen und Schüler:innen können direkt mit Expert:innen Kontakt aufnehmen und von deren Expertise profitieren (Präsentationen, Patenschaft für Maturaarbeiten, usw.). Je mehr Fachpersonen sich eintragen, desto einfacher wird es, junge Menschen für Naturwissenschaften zu begeistern. Deshalb unser Aufruf an alle Wissenschaftler:innen: Schenken Sie ein wenig Ihrer Zeit – und inspirieren Sie die nächste Generation!

Kennen Sie #WithScientists? Die Datenbank bringt #Wissenschaft und Jugendliche zusammen. Interessierte #Fachpersonen können sich eintragen und z. B. #Maturaarbeiten von Schüler:innen begleiten. Jetzt registrieren 👉 mint.scnat.ch/de/id/j7HNX

Comparison between fast-interrupted steady-state (FISS) and rapid water-excitation pulses for fat signal suppression in free-running whole-heart MRI at 1.5 T - PubMed The tested sequences performed similarly in SNR and CNR but LIBOR offered the lowest SAR, making it a promising candidate for applications where RF energy deposition is a concern.

New publication: Comparison between fast-interrupted steady-state (FISS) and rapid water-excitation pulses for fat signal suppression in free-running whole-heart MRI at 1.5 T. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40549260/
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Early Outcomes of Real-World Transcatheter Tricuspid Valve Replacement - PubMed TR elimination following TTVR in a real-world setting was associated with significant symptom and end-organ functional improvement. Patients with massive or torrential TR were more likely to experienc...

New publication: Early Outcomes of Real-World Transcatheter Tricuspid Valve Replacement. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40560107/
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Are you a PhD student?
Are you an LS2 member?

✈ Would you like to attend an international conference?
Then waste no time and apply for SCNAT-supported LS2 ✨travel grants✨ for PhD students until 1st of September 2025: buff.ly/dxp7aCU

Find out more: buff.ly/0BVzidi

Experience science in the heart of Bern! The Night of Research will bring over 80 research projects to the Grosse Schanze on September 6, 2025 from 4 p.m.
- Come and experience it for yourself — you'll be amazed! The CVRC will also be there, are you coming too?
unibe.ch/ndf
#ndfunibern
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The Fate of False Lumen in Type B and Residual Type A Aortic Dissection Using the Candy-Plug Technique: A Systematic Review and Meta-Analysis - PubMed CP technique appears to be a promising solution demonstrating high technical success, false lumen thrombosis, and aortic remodeling rate. However, the clinical success rate tends to be lower. Life-lon...

New publication: The Fate of False Lumen in Type B and Residual Type A Aortic Dissection Using the Candy-Plug Technique: A Systematic Review and Meta-Analysis. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40521780/
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Effect of individual nutritional therapy during inpatient pulmonary rehabilitation in patients at risk for malnutrition and sarcopenia - a randomized controlled trial - PubMed BackgroundMalnutrition and sarcopenia are common in inpatient rehabilitation, however individual nutritional therapy (iNT) is often underutilized. This study aimed to assess the effect of iNT on nutri...

New publication: Effect of individual nutritional therapy during inpatient pulmonary rehabilitation in patients at risk for malnutrition and sarcopenia - a randomized controlled trial. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40518743/
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Hemodynamic Characterization of Peripheral Arterio-Venous Malformations Using Rapid Contrast-Enhanced MR Imaging: An In Vitro and In Vivo Study - PubMed MR image quality and temporal resolution are sufficient to allow a classification of pAVMs. This classification method has the potential to become a diagnostic tool for the surgical navigation of pAVM...

New publication: Hemodynamic Characterization of Peripheral Arterio-Venous Malformations Using Rapid Contrast-Enhanced MR Imaging: An In Vitro and In Vivo Study. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40514606/
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Integrating gender medicine into modern healthcare: Progress and barriers - PubMed Recognising and addressing sex- and gender-sensitive health differences will lead to more personalised and effective medical care, ultimately improving health outcomes for all individuals.

New publication: Integrating gender medicine into modern healthcare: Progress and barriers. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40501433/
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IVUS Is Superior to OCT for the Visualization of Dynamic Anatomic Vessel Lumen Changes in Anomalous Coronary Artery - PubMed IVUS Is Superior to OCT for the Visualization of Dynamic Anatomic Vessel Lumen Changes in Anomalous Coronary Artery

New publication: IVUS Is Superior to OCT for the Visualization of Dynamic Anatomic Vessel Lumen Changes in Anomalous Coronary Artery. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40462357/
@chrisgraeni.bsky.social #CVRCBern

Quantitative susceptibility mapping in the human brain at 7T with phase-cycled balanced SSFP - PubMed The feasibility of phase-cycled bSSFP for QSM at 7T was demonstrated, with the added benefit of simultaneous <math> T 1 $$ {T}_1 $$ </math> , <math> T 2 </math> …

New publication: Quantitative susceptibility mapping in the human brain at 7T with phase-cycled balanced SSFP. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40457642/
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Voltage threshold adjustments for a novel pulsed-field ablation catheter with integrated mapping capabilities: lessons from a case series - PubMed This case series demonstrates that the VLCC provides satisfactory mapping performance in common use cases but requires voltage threshold adjustments for accurate visualization. Despite its ability to ...

New publication: Voltage threshold adjustments for a novel pulsed-field ablation catheter with integrated mapping capabilities: lessons from a case series. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40458772/
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👏 Congratulations to all awardees of the Day of BioMedical Research 2025 🏆 – Adrian Segiser, @noelledommann.bsky.social, @lianahay.bsky.social, Benedetta Coppe, Isabel Bärtschi, Fabio Ryser, Sebastian Jordi, Berenice Maier @unibe.ch 👉 tinyurl.com/yf9ndv5x

Benedetta Coppe receives the Johanna Dürmüller-Bol DBMR Research Award 2025🏆! She investigates how neonatal cardiac damage affects gonads and gametes in mice, with the ultimate goal of preventing the transmission of epigenetic changes in children with congenital heart disease.

Mechanical properties of 3D voxel-printed materials for cardiovascular tissue imitation - PubMed The novel 3D voxel-printing material approach resulted in reduced elastic modulus, anisotropic behavior, and strain-hardening properties, providing a much closer representation of the mechanical behav...

New publication: Mechanical properties of 3D voxel-printed materials for cardiovascular tissue imitation. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40521090/
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Join us to the International Symposium on Precision Cardiology! September 8, 2025! For more information visit our website www.cvrc.unibe.ch
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Feasibility and Impact of Left Atrial Appendage Closure in Patients with Cardiac Implantable Electronic Devices: Insights from a Prospective Registry - PubMed <span><b>Background</b>-Percutaneous left atrial appendage (LAA) closure (LAAC) offers a valid alternative to oral anticoagulation in patients with atrial fibrillation (AF) at high risk of bleeding. H...

New publication: Feasibility and Impact of Left Atrial Appendage Closure in Patients with Cardiac Implantable Electronic Devices: Insights from a Prospective Registry. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40507616/
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The DBMR Day of BioMedical Research 2025 is tomorrow! Join us – there will be plenty of good science to learn from! @unibe.ch @rgottardo.bsky.social ‪#Inselspital

📣 #Call for Project funding
Researchers can determine the nature and topic of their research projects independently. Open to all disciplines.

🗓 Submission deadline: 1 October 2025, 17:00 CEST.
➡️ buff.ly/Q1yW0oX

The role of connexin-43 in modeling arrhythmogenic diseases with induced pluripotent stem cell-derived cardiomyocytes - PubMed A common pathophysiological characteristic of arrhythmic diseases is the disruption of electrical signal transmission across the heart causing life-threatening rhythm disorders. These conditions are a...

New publication: The role of connexin-43 in modeling arrhythmogenic diseases with induced pluripotent stem cell-derived cardiomyocytes. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40436246/
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YouTube video by Swiss National Science Foundation NRP 79 – Advancing 3R: Watching the heart grow - in real time!

It is out now! Together with NRP 79 «Advancing 3R – Animals, research and society», we have produced a short video, explaining our team‘s work in the Swiss National Science Foundation SNSF‘s NRP79 program.
Video on Youtube youtu.be/0tUjkAOEpOY?...

Lack of junctional adhesion molecule (JAM)-B traps CD8 T cells in CNS border zones and ameliorates autoimmune neuroinflammation - PubMed The endothelial blood-brain barrier (BBB) tightly controls T cell entry into the central nervous system (CNS). T cell extravasation across the BBB involves a multi-step cascade with a predominant role...

New publication: Lack of junctional adhesion molecule (JAM)-B traps CD8 T cells in CNS border zones and ameliorates autoimmune neuroinflammation. Congratulations to the authors! pubmed.ncbi.nlm.nih.gov/40420242/
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Dissolving porcine and human microthrombi by short exposure to microdoses of alteplase in an in vitro model of microvascular obstruction Coronary microvascular obstruction (MVO) occurs in up to 57% of patients suffering from ST-segment elevation myocardial infarction (STEMI). One cause for MVO is distal embolization by microthrombi aft...

New publication: Dissolving porcine and human microthrombi by short exposure to microdoses of alteplase in an in vitro model of microvascular obstruction. Congratulation to the authors! pmc.ncbi.nlm.nih.gov/articles/PMC...
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