@profmarciniak.bsky.social
Professor of Respiratory Science University of Cambridge. Lung doctor. Fellow St Catharine’s College. Cell biology. Pleural medicine. Rare disease. Genetics. Lab webpage = https://www.cimr.cam.ac.uk/staff/professor-stefan-marciniak
She warned that “one should … not assume that progress towards equality is inevitable and irreversible.”
Since neurokinin 3 receptor antagonism is in the news as a new treatment for menopause symptoms, here’s one of the important studies from 3 years ago that demonstrated effectiveness
www.sciencedirect.com/science/arti...
Proton beam hope for asbestos cancer patients
#mesothelioma
www.bbc.co.uk/news/article...
Or even
Some disturbing posts and behaviour being seen on this site recently. Don’t let what happened to Twitter happen here.
Report and block.
I won’t engage with such nonsense.
She explained to her husband, who was there to help host the event, that she knew me when I was a “bay doctor”. He thought she meant I was a neonatologist back then. But no, she very very junior 👶🩺🍼
Quite simply, the disinformation spread by RFK Jr and his fellow charlatan’s will hurt more and more children until the burden of misery cannot be ignored by the policy / lawmakers - and the electorate that empowers them.
Enjoyed talking with the Papworth Mesothelioma Social Group (patients, families, carers) about some of our most recent mesothelioma discoveries
Lovely to catch up with the great Lavinia Magee who was a senior meso nurse at @royalpapworth.bsky.social when I was a trainee
www.papworthmesosocial.com
GCN2 in proteostasis: structural logic, signalling networks and disease
febs.onlinelibrary.wiley.com/doi/10.1111/...
Whoops Apocalypse, 1986
An Iranian leader falls, world powers blunder, Russia threatens
A Labour gov faces an aggressively posturing US administration
I’m really not sure why this 1980s political comedy, in which the world nearly ends by mistake, came to mind
Celebrating the efforts that many scientists put into understanding and curing #rarediseases
+++investment needed!!
11 years for me working on #CF #IPF, now #BHD #FPF @lifearc.bsky.social
@profmarciniak.bsky.social @jennydickens41.bsky.social
@thecimr.bsky.social
@universitypress.cambridge.org
Diversity should be a strength. We think differently, behave uniquely, contribute individually
But populists target difference. They identify a small, weak group—they wouldn’t pick on strong billionaires—and encourage the majority first to fear, then to hate them
Don’t be manipulated by populism
Her work was v important. She used her chemistry knowledge to alter the pharmacokinetics (PK = how the body handles a drug) of chaulmoogra oil, which was available for leprosy but limited by its PK. We still don’t know how the oil works, but her advance was to turn it into water‑soluble ethyl esters
Ah that old chestnut: instruction of the poor risks raising them above “their proper station”
bsky.app/profile/prof...
VIR‑5500 shows strong activity in advanced prostate cancer in phase 1 trial with minimal toxicity. Many showed tumour shrinkage, incl. complete resolution of liver mets in one case. Not yet peer‑reviewed; larger trials planned.
www.theguardian.com/society/2026...
My lab on this day in 2014 ❤️🥼🧬
Vruti is now in pharma
Lizzy is an oncologist
Jenny is a PI in CIMR
Elke is a scientist in Holland
Caia works in pandemic preparedness
Hannah is a dietitian
Alex is a PI in Manchester
Adriana is a PI in Spain
Joe is senior research scientist
@thecimr.bsky.social
Care roles hit particularly hard by UK’s lurch to the right on migration, according to analysis of Home Office data
www.theguardian.com/society/2026...
One of my lovely PhD students has a place medical school in the US after she finished here. As a thank you for helping her prepare for interviews* she had this mug made with my favourite NHS quote on it
*I would say she got in _despite_ my help. I can’t believe my lefty views would have helped her😆
In which we show that Tatton-Brown-Rahman syndrome due to a pathogenic variant of DNA methyl transferase DNMT3A can be associated with Familial Pneumothorax 🫁🧬
#RareDisease
#Pneumothorax
@cuh.nhs.uk
@royalpapworth.bsky.social
www.nature.com/articles/s41...
Congratulations to our Fellow Stefan Marciniak (2011) on receiving a #RareDisease Science Grant from the EQT Foundation to progress AI-enabled diagnosis of Birt-Hogg-Dubé syndrome, a rare genetic disorder affecting skin, lungs & kidneys: eqtgroup.com/eqt-fou...
📸 Stephen Bond/CIMR
A welcome U-turn
Hopefully a sign RFK’s antivaccine faction is being marginalised
FDA political appointee Prasad had first overruled FDA scientists. Then POTUS reported to have pressured FDA Commissioner Makary. Next, FDA agreed to review the application
www.theguardian.com/us-news/2026...
A lot of people, including me, were wondering how an IRB could ever approve this study.
The answer is that no IRB did. The person who “signed off” on approval from the only ethics board that reviewed it had resigned three years earlier. His signature was used without his knowledge.
Pediatricians are cool to begin with
Now their blood is being used to make new treatments for RSV and colds! 👏🏽👏🏽
www.newscientist.com/article/2516...
Zarah just sent me this nice photo of Noor, Zarah and me in front of John Addenbrooke’s late 17th early 18th century medical book collection
#GirlsInSTEM
All the pupils were terrific
It can be nerve wracking to give a scientific talk to a packed room of fellow students and some university professors
Here they’re getting certificates from Julian Rayner, our head of department
School pupils Noor and Zarah spent a few days in our lab at @thecimr.bsky.social over half-term as part of the ISAC/M programme. Their mini projects had them studying cellular senescence & antitrypsin polymerisation respectively
Their talks at @stcatharines.bsky.social today did us proud 🥹🔬🧬
Today local pupils who spent part of their half-term having lectures and doing experiments in @thecimr.bsky.social will have a day in @stcatharines.bsky.social learning about university life and giving talks about the experiments they did.
www.cimr.cam.ac.uk/inspiring-sc...
