MüllerLab

Are i‐Motif Structures in DNA Compatible with Cytosine–Ag(I)–Cytosine Base Pairs? An i-motif/duplex junction was evaluated with respect to its ability to replace the protons from the hemi-protonated C:CH+ pairs by AgI ions to form C–AgI–C base pairs. Interestingly, only one such m...

Excited to share our study "Are i-Motif Structures in DNA Compatible with Cytosine–Ag(I)–Cytosine Base Pairs?" in @angewandtechemie.bsky.social 🧬

Congrats to Vicky and thanks to Miguel Galindo, Bernie Kraatz and everyone else involved for this collaboration 🎉

🔎Check it out: doi.org/10.1002/anie...

24.11.2025 14:31 — 👍 7    🔁 0    💬 0    📌 0

A high school student holding a large methane flame in her open hand.

Prof. Denise Steiner informs high school students about drug production in a lecture hall.

In the biochemistry lab, Bianca Berkenfeld explains to 7 high school students how to do a bacteria streak.

Two PhD-students prepare ice cream using liquid nitrogen. Beneath a blue sky outside, the working desk is covered with fog from water condensing from the cooled air.

Open doors for future chemists, food chemists, and pharmacists: More than 900 guests explored our labs and lecture halls at the yearly University day @uni-muenster.de .
Photos: Valerie Hollwedel, Hauke Engler

14.11.2025 10:01 — 👍 4    🔁 2    💬 0    📌 0

Congrats to our freshly minted Dr. Mai 🎉

Expert in DNA synthesis, master of ImPhen and now off to new adventures 🧬 We’ll miss him after some fantastic years, all the best for your future!

10.10.2025 14:43 — 👍 9    🔁 0    💬 0    📌 0

Team outing with the work group - great weather, great vibes and even a round of golf with a surprisingly solid performance on the course 😉⛳️

15.09.2025 12:20 — 👍 10    🔁 0    💬 0    📌 0

Redirecting

Congrats to Florian on his publication investigating 5-fluorouracil in metal-mediated base pairing🥳 Check it out: doi.org/10.1016/j.ji... 🧬

01.09.2025 10:24 — 👍 5    🔁 0    💬 0    📌 0

What an honor for Carla to present her research at the Ph.D. graduation ceremony. Well deserved and well done! Now it's time to celebrate Tabea and Carla 🥳

12.07.2025 12:20 — 👍 6    🔁 0    💬 0    📌 0

Proud supervisors today as Tabea successfully defended her Ph.D. thesis. Congrats Dr. Lenz and all the best for your future 🚀🔥

04.07.2025 12:31 — 👍 12    🔁 0    💬 0    📌 0

Congratulations to Carla for successfully defending her thesis today!🥳

Thank you for an amazing time and all the best for your future, Dr. Bardehle!

13.06.2025 15:24 — 👍 19    🔁 0    💬 2    📌 0

Lumos: A β‐Diketone‐Derived Artificial Nucleobase Forming Inter‐Strand Complexes in DNA that Promote Lanthanoid Ion Luminescence The Cover Feature shows a parallel-stranded DNA duplex with a terminally attached luminescent lanthanoid complex, represented by a magic wand that lights up when the corresponding spell is cast. The ....

Lumos! Carla developed a magic wand promoting lanthanoid ion luminescence in DNA duplexes 🧙‍♀️

Check out the cover image @ChemistryEurope (doi.org/10.1002/ceur...) 🥳

#OpenAccess

16.05.2025 09:49 — 👍 7    🔁 0    💬 0    📌 0

Determination of silver(I)-binding sites in canonical B-DNA by NMR spectroscopy

We are excited to share the publication of our latest work in JBIC! 🥳 This study sheds light on how silver ions interact with canonical nucleic acids, using advanced NMR spectroscopy.

🔗  rdcu.be/ekuNi

Congratulations to Tabea and the entire team 🇩🇪🇸🇮

05.05.2025 10:51 — 👍 8    🔁 0    💬 0    📌 0

Water-soluble luminescent platinum(II) complexes for guanine quadruplex binding A family of 16 platinum(ii) complexes was synthesized with the aim of obtaining water-soluble luminescent coordination compounds for guanine quadruplex (G4) binding. The complexes share a common tride...

Want to learn more about water-soluble luminescent platinum(II) complexes for guanine quadruplex binding? Check out the full paper of this collaborative Müller/Strassert work @daltontrans.rsc.org (doi.org/10.1039/D4DT...)

Congrats to Simon, Marian, Alex, Marcus, Joschua and Ali 🎉

26.03.2025 10:56 — 👍 10    🔁 1    💬 0    📌 0

Tuning the Duplex Stability of DNA Oligonucleotides Containing Metal‐Mediated Base Pairs of Imidazole‐Derived Nucleobases The formation of metal-mediated base pairs comprised of HQIm (3H-imidazo[4,5-f]quinolin-5-ol) and/or CaIm (imidazole-4-carboxylate) induces a significant thermal stabilization of DNA with the 3d meta....

👏🏽Congrats Carla, on publishing your first paper this year! 🎉 This study explores metal-mediated base pairing with cobalt, nickel, zinc, and even lanthanoids to tune duplex stability, paving the way for new applications in DNA chemistry!

📄Read more: dx.doi.org/10.1002/chem...

11.03.2025 13:54 — 👍 14    🔁 1    💬 0    📌 0

We're excited to announce the launch of our new Bluesky account @mueller-lab.bsky.social 🎉 Along with this, we're thrilled to welcome our new PhD students Nele, Julian, Luca and Rafael! Stay tuned for updates and insights from our team! 🚀👨🏽‍🔬👩🏼‍🔬

21.02.2025 11:11 — 👍 14    🔁 0    💬 0    📌 0