CRC 1064 Chromatin Dynamics

CRC 1064 Chromatin Dynamics

@crc1064.bsky.social

Munich research consortium focusing on chromatin dynamics.

85 Followers 46 Following 6 Posts Joined Nov 2024
2 months ago

We probably shouldn’t have favourites amongst projects in the lab, but this one was mine. I’m so pleased we can finally share it:

Our work is now out in Nature Communications:
🔗 nature.com/articles/s41467-025-67692-7

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2 months ago

Excited for this new preprint from my lab where we unexpectedly found a role for methionine synthase reductase in regulating heterochromatin independently of methionine synthesis 👇

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2 months ago
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H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations Nitsch et al. show that short-chain acylations of histone H4K16, acetylation (C2), propionylation (C3), and butyrylation (C4) modulate chromatin structure in vitro. These effects can translate in vivo...

Now final version out: Our manuscript connecting histone modifications with metabolism: How H4K16 acylations regulate inter +intranucleosomal interactions and confer resilience to metabolic challenges in vivo. Thanks to the team+ @sandrani.bsky.social

Enjoy 👇👇 www.cell.com/molecular-ce...

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3 months ago

Menno Schilthuizen @schilthuizen.bsky.social gave a brilliant overview of the interplay between genetic diversity and reproductive isolation in speciation, followed by a discussion with science historian Kärin Nickelsen and biochemist Axel Imhof @bmc-lmu.bsky.social. Chair: @lenabouman.bsky.social

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3 months ago

I feel extremely honoured for this recognition. Thanks go to many people from my lab and colleagues for their trust and support over the years

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3 months ago
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Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon Nature Communications - Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon

We are honored to share our Perspective in Nature Communications, reflecting on the legacy of John B. Gurdon.
Beyond his discoveries, his generosity and curiosity inspired a community of scientists-we remember and celebrate his lasting impact. #JohnGurdon #Xenopus #NatureCommunications

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3 months ago
A Platform for Emerging Talent: The Helmholtz Munich Talent Forum 2025

🌍 The #HelmholtzMunich Talent Forum 2025 brought together exceptional early-career scientists in #epigenetics & nucleic acids research to foster exchange, collaboration & research excellence. 👩‍🔬👨‍🔬

👉 t1p.de/3dsix

@boyanbonev.bsky.social @epihmgu.bsky.social
#TalentForum

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3 months ago
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The Helmholtz Munich Talent Forum (Nov 18–19) brought 8 emerging global talents in epigenetics & nucleic acids research to our Neuherberg Campus! Inspiring talks, a keynote by @boyanbonev.bsky.social & vibrant networking—science at its best! bit.ly/4o2ftxr

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4 months ago
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🔬 Exploring Frontiers in Epigenetics & Nucleic Acids
Join us @ Talent Forum 2025 – a 2-day symposium spotlighting top early-career researchers.

📅 Nov 18–19 | Helmholtz Munich
🎙 Keynote: Prof. Boyan Bonev
🌍 Speakers from around the world
🎟 Free registration: www.helmholtz-munich.de/stem-cell-ce...

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4 months ago
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“Translating complex science into something simple, yet meaningful is never easy.” 💬
Our #EpiCrossBorders PhD researchers are learning just that — turning #epigenetics into connection, curiosity & conversation at the Deutsches Museum.
📍14–16 Nov | #StemCellStories #SciComm #PhDLife

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5 months ago
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🧬 From 14–16 Nov, join us at the #DeutschesMuseum for “Stem Cell Stories” — an interactive exhibition on stem cells, identity & epigenetics.
🎙️ Roundtable discussion on #AI in stem cell research & its ethical challenges on 📅14 Nov ⏲️18:30.
#StemCells #Epigenetics #AIinBiomedicine #HelmholtzMunich

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7 months ago
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Replisome progression regulates R-loop mediated transcriptional repression Maintaining cellular proliferation necessitates the synchronized activity of diverse molecular machineries operating in parallel on the genome. Wide-spread transcription and R-loop formation can inter...

Our latest research is online in the @biorxivpreprint.bsky.social! 🧬🎉

🔎 We have developed a novel, single-cell real-time approach to monitor R-loop generated TRCs, and we have shown R-loop-mediated, replisome-controlled transcription repression.

www.biorxiv.org/cgi/content/...

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6 months ago
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Recognition and remodelling of nucleosomes and hexasomes by the human INO80 complex The ATP-dependent INO80 chromatin remodeller slides and repositions nucleosomes to shape and maintain chromatin around gene regulatory elements and replication origins. Recent work uncovered capabilit...

Check out our pre-print on how the human INO80 complex acts on nucleosomes and hexasomes: PostDocs Priyanka & Manmohan et al. solved structures of INO80 bound to several substrates and completed missing questions about similarities of modes of actions across species🧬 www.biorxiv.org/content/10.1...

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5 months ago
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#Jobalert 🚨: Please RT !
Looking for a #PhD student for exciting project on the interphase between epigenetics and cellular metabolism:
How do (nuclear) metabolic enzymes reguate chromatin function ?
#epigenomics, #epigenetics, #metabolism
www.helmholtz-munich.de/en/ife/job-o...

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5 months ago
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🎙️ Chromatin and Neurodevelopment: An Interview with Prof M. Felicia Basilicata 🎙️
We are pleased to welcome Prof Basilicata, who joined our BMC as LMU Professor of #Molecular #Gene #Regulation on 1st Sep.

🧬 Read the interview ➡️ lnkd.in/eR9ptAWf

Foto: BMC / #chromatin #neurodevelopment #disorder

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6 months ago
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LMU remains the best German university In the latest Academic Ranking of World Universities, LMU ranks among the world’s top 50 research-intensive universities.

LMU remains the best German university www.lmu.de/en/newsroom/...

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7 months ago

Now peer reviewed and in its final form @natcomms.nature.com

www.nature.com/articles/s41...

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7 months ago
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MUG prizes for LMU early-career researchers This year, six doctoral graduates and two habilitation graduates are receiving awards from the Munich University Association.

🥳Congratulations, Shubo! 🥂👏What a fantastic start to your scientific career!
Shubo Zhao @jstingele.bsky.social receives Promotion Award from the Münchner Universitätsgesellschaft:
www.genzentrum.uni-muenchen.de/news-events/...
MUG prizes for LMU early-career researchers www.lmu.de/en/newsroom/...

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7 months ago
Talent Forum Applications Close July 31

📢 Advance Your Career: Apply by July 31 to speak at the #TalentForum at #HelmholtzMunich!

#PostDoc aiming for a group leader role? Present your work in #Epigenetics & Nucleic Acids Research and connect with leaders in the field.

🗓️ Nov 18–19, 2025, Munich
⏳Deadline: July 31, 2025

👉 t1p.de/n2n2r

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7 months ago
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🎉 Join us at the upcoming GfG Symposium "Epigenetics & Chromatin" in Giessen, Sept 24–26, 2025!
Amazing speakers, low registration fee, € 300 prizes for best poster & short talk, + free GfG membership for non-members.

Please RT!

express.converia.de/frontend/ind...

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7 months ago
Die Rolle Künstlicher Intelligenz in der Wissenschaft
DFG Blog-Reihe für Open Access Network

Welche Bedeutung hat Künstliche Intelligenz für #OpenScience? Was wird dazu in der wissenschaftlichen Community diskutiert? Diesen Fragen widmen sich 3 Blog-Beiträge von DFG-Kolleg*innen für das Projekt "Open Access Network", wo nächste Woche bereits der dritte erscheint.
▶️ open-access.network/blog

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7 months ago
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🎤 Apply to speak @our TALENT FORUM by July 31!
Showcase YOUR research in Epigenetics & NucleicAcids @www.helmholtz-munich.de & connect with leading scientists

🧳Travel+accommodation covered if selected!
📝 Info+how to apply: lnkd.in/drkRvz7N

#postdoc #career #groupleader #HelmholtzMunich #research

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7 months ago
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Leistungsdimensionen und Bewertungskriterien - Wissenschaftliche Integrität Für die Bewertung der Leistung von Wissenschaftler*innen ist ein mehrdimensionaler Ansatz erforderlich: Neben der wissenschaftlichen Leistung können weitere Aspekte Berücksichtigung finden. Die Bewert...

#WissenschaftlicheIntegritaet: Welche Kriterien sind eigentlich für die Bewertung der #Leistung von Wissenschaftler*innen relevant? Den mehrdimensionalen Ansatz und Fragen rund um #Leistungsdimension und #Bewertungskriterien (er)klärt unser #GWP-Kodex in Leitlinie 5: fcld.ly/leitlinie5

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7 months ago

Hear, hear, one of the most remarkable colleagues (and dearest friends) I've had just became Dr Pal!!! My warmest congratulations to you Mrinmoy, and can't wait to see all the amazing things you will do in the future!!!

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9 months ago
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CTBP2 as an oligomerization-dependent bridge between pro-inflammatory transcription factors & co-repressors that balances the expression of inflammatory genes @www.helmholtz-munich.de‬ @franzigmuc.bsky.social‬ @crc1064.bsky.social‬ @tum.de www.life-science-alliance.org/content/8/8/...

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9 months ago
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Our closing CRC 1064 Chromatin Days (May 26–27) brought together past & present members for inspiring talks, posters, and a celebration of 12 years of collaboration. Huge thanks to all speakers, contributors & participants—what a send-off! The IRTG lives on 🎉 #ChromatinDays #ScienceCommunity #Munich

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9 months ago
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🎤 Postdocs: want to take the next step and become a #PI?

Apply to speak at the TALENT FORUM @www.helmholtz-munich.de, showcase your research in Epigenetics & Nucleic Acids, and connect with top scientists.

🧳 Travel & accommodation covered if selected!

📝 Apply by 31July.

🔗 Info: lnkd.in/drkRvz7N

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9 months ago

The tension is rising 😀 The draw for the ten winning teams of the “Best Research Environment” award will take place on Saturday (7.6.) @jungeakademie.bsky.social . /// Die Spannung steigt 😀 Am Samstag (7.6.) findet die Auslosung der 10 Gewinnerteams statt. Drückt uns die Daumen!

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9 months ago
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Chancengleichheits-Monitoring Das "Chancengleichheits-Monitoring" berichtet jährlich über die Beteiligung von Wissenschaftlerinnen an DFG-Projekten.

Chancengleichheit von Wissenschaftlerinnen und Wissenschaftlern hat die DFG als Ziel in ihrer Satzung verankert. Mit dem Monitoring stellen wir jährlich Statistiken bereit, die den Frauenanteil bei Antragstellung und -erfolg, Begutachtungen und DFG-Gremien abbilden. 1/2
www.dfg.de/de/aktuelles...

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9 months ago
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Changes to the 2026 and 2027 Work Programmes With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...

Planning to apply for #research #funding from the ERC?

From the next application rounds, expect changes to the:

• proposal structure
• evaluation process
• extra funding you can request
• eligibility for Starting & Consolidator #Grants (from 2027)

More 👇 europa.eu/!RPHWvv

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