Interesting and systematic evaluation that consolidates many observations the field has already been converging on: GPX4 dependency appears to be overestimated in vivo. Suggesting that exploiting high-PUFA states in specific cancer entities is unlikely to benefit from single-target GPX4 inhibition.
Interesting and systematic evaluation that consolidates many observations the field has already been converging on: GPX4 dependency appears to be overestimated in vivo. Suggesting that exploiting high-PUFA states in specific cancer entities is unlikely to benefit from single-target GPX4 inhibition.
Hei Derek!
Thanks a lot 😊
#Vitamin B2 is converted into molecules which protect cells from oxidative damage. The downside: It also protects #cancer cells. Scientists at the Rudolf Virchow Centre at #JMU discovered that. 📸 Natalie Fahmer
➡️ www.uni-wuerzburg.de/en/news-and-...
also see the study from @olzmannlab.bsky.social who independently report on the importance of vitaminB2 on
ferroptosis
www.nature.com/articles/s41...
Happy to share the final version of the study where we describe a central role for vitaminB2 in regulating membrane redox state - some new cool experiments were added since the preprint was posted - pls check this out
thttps://www.nature.com/articles/s41556-025-01856-x
🧐 What if metabolic defects are not just a consequence of inflammatory disease - but actively contribute to it?
Inflammation and metabolism are deeply intertwined, but the molecular links remain unclear.
Our new paper in Cell Death & Differentiation uncovers one. 🧵👇
nature.com/articles/s41...
It's shaping up to be an amazing line up at the Gordon Cell Death meeting! Register now! www.grc.org/cell-death-c...
It feels like anything, no matter how bizarre, is on the table 🤬
In 🇧🇷portuguese this will be cleanly translated to "Capitão do mato" -
you cant make this stuff up...
en.wikipedia.org/wiki/Slave_c...
BREAKING: The two federal immigration agents who fired on Minneapolis protester Alex Pretti are identified in government records as Border Patrol agent Jesus Ochoa and Customs and Border Protection officer Raymundo Gutierrez.
Modern lipid biology has grown far beyond its roots. Advanced technologies offer novel opportunities to unravel the role of lipids in the organization of biological systems. Build on this momentum and join The EMBO Workshop "The Lipid Code to Life" Sept 7-11, 2026 meetings.embo.org/event/26-lip...
In today’s European politics, consensus is dead, unless the topic is Greenland. Thanks, Trump.
seems like the second Dark Age has officially started
The unimaginable is happening in the US government, but the muted response of Americans against it surprises me. Brazilians may have something to contribute, explaining how to organize a good Panelaço (which in English is apparently a "casserole protest"): en.wikipedia.org/wiki/Cacerol...
„Never forget: whenever Elon Musk walks up to a podium to bullshit you about colonizing Mars or whatever, he is walking on the bodies of dead children. He yanked their food and medicine away while telling lies and cracking stupid jokes.“
@dereklowe.bsky.social as usual not pulling any punches
🤷♂️
Things will improve in 2026
🫏
If 2025 was a lot… here’s a reminder: keep moving, keep flowing 🌊
Happy holidays from Foz do Iguaçu 🇧🇷
We are hiring dedicated and motivated new members to join our basic and clinical research team at INIMS (www.inims.de), Universitätsklinikum Hamburg-Eppendorf.
- Medical Scientist (Postdoc)
- Clinician Scientist (Neurology)
Apply here:
www.uke.jobs/index.php?ac...
www.uke.jobs/index.php?ac...
If 2025 was a lot… here’s a reminder: keep moving, keep flowing 🌊
Happy holidays from Foz do Iguaçu 🇧🇷
We have a great line-up of speakers including:
Jennifer Andexer, Helge Bode, Stephan Hammer, Akane Kawamura, Alexandria (Ali) Deliz Liang, Carina de Oliveira Mann, Stefan Raunser, Schraga Schwartz, Pierre Stallforth, Carine Tisné, Satpal Virdee, Wilfred van der Donk
#Chemistry #Meeting
CC: @gdch.de
Are you interested in cutting-edge #Biochemistry and #ChemBio? Join us for the GDCh #Biochemistry2026 conference in Würzburg on March 16th to 18th, 2026.
Registration is now open and you can submit an abstract until January 10th, 2026: veranstaltungen.gdch...
(1/2)
2025 feelings -
www.cnn.com/2025/12/17/p...
That’s not politics. That’s basic lack of adult supervision.
🔬 PhD opportunities in Würzburg, Germany!
The RTG 3190 is offering 11 funded PhD positions focused on thrombo-inflammation.
📅 Apply by January 16, 2026
👉 Don’t miss your chance to be part of a new DFG-funded research training group!
#platelets #thrombo-inflammation #inflammation #megakaryocyte
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
