Lindsay Meyers (she/her)

Join us at #ACMG2025

We will be showcasing our upcoming rare disease products in our showcase, Advancing Rare Disease Diagnostics, on March 19th at 12:15 PM PST. Lunch will be provided. Register here: lnkd.in/gP847QVR

🚨 New paper alert! 🚨
Using SHaRe registry data, we explored how clinical & genetic risk factors influence heart failure, arrhythmias, and mortality in men & women with HCM.
This study, from my PhD, emphasises the need for sex-specific approaches to improve care.

📖 Read more: bit.ly/41vlF9r

MyOme and Novi Health Collaborate to Bring Whole Genome Testing to Employer Health Programs /PRNewswire/ -- MyOme, a leading clinical innovation whole genomic analysis and polygenic risk modelling (PRS) company announced a strategic partnership with...

We're partnering with Novi Health to bring whole genome testing to employer health programs. Through this collaboration, employees and their families gain access to whole genome sequencing, integrated risk (with PRS) reports, and expert genetic counseling.
prn.to/4jzWF7T

Pretty big deal. @bookshop-org.bsky.social is selling ebooks now. You can now support indies while purchasing digital books.

bookshop.org/ebooks

Genome sequencing in male breast cancer reveals new pathogenic variants beyond BRCA1/2, increasing diagnostic yield to 33% and highlighting polygenic and monogenic contributions to disease risk bit.ly/3CbJXLx

A health systems assessment of genetic counseling in cardiovascular care in a large health system: Adherence to genetics recommendations in the Military Health System - PubMed Genetic counseling and genetic testing are important tools for diagnosis, screening, and employment of effective medical management strategies for hereditary cardiovascular diseases. Despite widesprea...

Another study shows cardiovascular genetic testing (CVGT) underutilization and provides new evidence of genetic counseling (GC) underutilization. Sneak peek at cardiomyopathy (CM) and arrhythmia (ARRH) data: 1% with CM and 0.7% with ARRH had GC; only 0.84% had GT. pubmed.ncbi.nlm.nih.gov/37766662/

🎉 The HEARTS Act has passed the Senate & heads to President Biden's desk! HRS, a proud Smart Heart Sports Coalition member, led a grassroots effort urging legislators to act. Soon, schools nationwide will have AEDs, CPR training, & emergency plans—lifesaving tools for every kid ❤️smartheartsports.com

Natera and MyOme Announce Launch of iPRS™ for Breast Cancer Risk Assessment Cross-ancestry polygenic risk score now offered with the Empower™ hereditary cancer test AUSTIN, Texas–(BUSINESS WIRE)– Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA and genetic testin...

Big news! 🧬 Natera & MyOme launch iPRS™, a personalized tool to assess breast cancer risk. Backed by research, iPRS integrates >1M genetic markers & clinical inputs for accurate, cross-ancestry insights.

Learn more: ow.ly/mGsJ50UntLt
#BreastCancer #Genetics

Here are some cardio ones!

🦋 Follow #CardioSky community by using starter packs:
Cardio Journals & Societies
go.bsky.app/FfE1QRm
CardioSky I
go.bsky.app/562nfhZ
CardioSky II
go.bsky.app/R2XckyG

🦋 Add label "Cardiology" to your profile w/labeler
bsky.app/profile/meds...

Sharing the @americanheart.bsky.social scientific statement about asssessing & addressing CV health in individuals who are transgender and gender diverse. Transgender care is health care, and I support optimizing the lives & hearts of all persons. 🏳️‍🌈
www.ahajournals.org/doi/10.1161/...

Lipoprotein(a) levels in a population with clinical atherosclerotic cardiovascular disease in the United States: A subanalysis from the Lp(a)HERITAGE study Cardiovascular disease (CVD) is the leading cause of death worldwide, responsible for an estimated 27% of deaths in the United States (US) in 2021.1 Globally, almost 20 million deaths were caused by CVD in 2021, which represents an increase of approximately 21% since 2010.1 Elevated lipoprotein(a) (Lp[a]) is the most common genetic dyslipidemia,2 affecting approximately 1.5 billion people worldwide. Evidence from both epidemiological and genetic studies identifies elevated Lp(a) as independently and causally associated with increased atherosclerotic cardiovascular disease (ASCVD) risk.

black or female, test lp(a)

'One-third of participants demonstrated Lp(a) levels ≥125 nmol/L, the threshold for high ASCVD risk, which was higher among Black (1/2) and female (2/5) participants, suggesting a greater need for Lp(a) testing'
#cardiosky #cvprev
www.lipidjournal.com/article/S193...

Great collaborative work spearheaded by M. Ardissino showing that, among those sustaining early-onset myocardial infarction, a CAD polygenic risk score was the strongest among assessed predictors of recurrent events www.ahajournals.org/doi/10.1161/... @ahajournals.bsky.social

The GLGC is a global collaboration of 100s of scientists interested in lipid genetics. Check out our recent review, where we highlight 🔑 contributions from the GLGC across the last 15 years.

👇

#CardioSky #Genetics #Lipids #GWAS

I would love to be added!

I couldn't spot a starter pack for rare disease / clinical genomics, so I started one: go.bsky.app/SUWZ9Hw

Very much a work in progress, and biased by who I have already found here, so please suggest people to add! Self-nominations encouraged.

#ClinicalInformatics #genomics #bioinformatics 🖥️🧬

Among British Pakistani & British Bangladeshi individuals, partitioned T2D polygenic load for insulin deficiency & lipodystrophy was higher than white European individuals & predisposed to faster progression to T2D & complications www.nature.com/articles/s41... @natureportfolio.bsky.social