Filippo D’Amico

ping @tscquizzato.com @filippodamico.bsky.social

Table 3. Clinical Outcomes.

Presented at #CCR25:

In the ANH phase 3 trial involving adult patients undergoing elective cardiac surgery, acute normovolemic hemodilution did not reduce the number of patients receiving allogeneic red-cell transfusion. Full trial results: nej.md/3FxdMrW

@criticalcarereviews.com

#ISICEM25 | Cardiac-Synchronized Mechanical Ventilation? 🫁❤️

🔬 Markus Skrifvars explores its impact:
✅ Higher PaO₂ & lower PaCO₂ with no pressure differences
❓ Key question: Are pneumothorax findings relevant to humans, or is this an effect seen only in pigs? 🐷

#ISICEM25 | Key Questions in Advanced Airway Management 🫁❓

🔥 Ari Moskowitz highlights ongoing debates:
🔹 Best device? ETI vs. SGA 🤔
🔹 Video vs. Direct Laryngoscopy 📹
🔹 When to intubate? Timing remains unclear ⏳
🔹 Should strategy vary based on arrest etiology, rhythm, or location?

#ISICEM25 | Key Questions in Advanced Airway Management 🫁❓

🔥 Ari Moskowitz highlights ongoing debates:
🔹 Best device? ETI vs. SGA 🤔
🔹 Video vs. Direct Laryngoscopy 📹
🔹 When to intubate? Timing remains unclear ⏳
🔹 Should strategy vary based on arrest etiology, rhythm, or location?

#ISICEM25 | Ari Moskowitz on Controversies in Airway Management during CPR 🫁🚑

🔹 OHCA: RCTs suggest SGA may be as good or better than ETI, based on operator skill.
🔹 IHCA: Limited data—observational studies lean toward no intubation
🔹 Ongoing trials comparing SGA vs. ETI for IHCA.

#ISICEM25 | IV vs. IO Access—Key Takeaways 💉🦴

📢 Markus Skrifvars on why IV remains the first choice:
✅ Higher ROSC rate
✅ Standard method for non-cardiac arrest patients
✅ As fast as IO in most cases
✅ Less expensive

#ISICEM25 | IV vs. IO Access—What’s the Best Choice? 💉🦴

🔍 Markus Skrifvars explores the pros & cons:
✅ IO is as good as IV—but not better
💰 More expensive & should be second choice after IV
🚑 Useful in EMS for patients with difficult access (e.g., children)
⚡ No faster than IV

#ISICEM25 | 🏥 New Guidelines for Perioperative Cardiac Arrest 🔄❤️

📢 Sharon Einav presents the methodology & PICO questions shaping the upcoming recommendations.

🔹 Evidence-based updates coming in the next few months!
🔹 Focus on best practices for managing cardiac arrest in surgical patients.

#ISICEM25 | 🚑 CPR Session Starting Now! 🚑

Moderated by Michel Slama & @fabio_taccone, this session dives into the latest advances in cardiopulmonary resuscitation

#ISICEM25 | 🏆 POSTER AWARDS 2025 🏆

👏 Xavier Monnet presents this year’s best research contributions!

📊 431 abstracts submitted
✅ 321 abstracts accepted
🏅 4 awards + 1 ISF (International Sepsis Forum) award

A celebration of innovation and excellence in intensive care research!

#ISICEM25 | Lennie Derde asks: Why is nobody using SDD despite strong evidence? 🤔💊

📊 Thousands of patients, consistent data, and mortality reduction, yet SDD remains underutilized.

🔹 Open questions:
•Availability
•Optimal regimen
•Impact on microbiome

#ISICEM25 | Paul Elbers on when to stop antibiotics—insights from data science 🔬💊

🔹 19% of patients had antibiotics reinitiated frequently

Reinitiating antibiotics is linked to:
📈 Longer ICU stay (22.0 vs. 15.9 days)
⚠️ Higher 90-day mortality (40% vs. 25%)

#ISICEM25 | Antoni Torres on when to stop antibiotics in severe CAP 🦠💊

🔹 Outpatients: ≤5 days if stable
🔹 Non-severe inpatients: <5 days (minimum 3)
🔹 Severe CAP: ≥5 days if stable

Key question: Can clinical stability criteria from CAP be applied to SCAP patients on mechanical ventilation?

Guys. Isicem is on Bsky. And follow @filippodamico.bsky.social and @tscquizzato.bsky.social for isicem tweets !!

👏🏽👏🏽👏🏽👏🏽👏🏽

#ISICEM25 | Always fascinating to hear @MichardFrederic discuss the future of bedside screens 🖥️🔍

📊 Evolution to visual decision support tools
🔹 Turning data into knowledge
⚡ Faster & more accurate detection of abnormalities
🧠 Improving situation awareness & reducing cognitive workload

#ISICEM25 | Michard Frederic on the future of bedside monitoring! 🚀📊

🔹 New ways to display monitoring variables
🔹 Advanced tools to visualize data
🔹 Seamless data integration into a single monitor
🔹 Data fusion—combining variables into one visual tool

#ISICEM25 | Vitaly Herasevich on building smart alerts in critical care ⚡🔍

🔹 No perfect detection algorithm exists—manual confirmation is key
🔹 Visual decision support tools enhance clinician feedback
🔹 Real-time compliance reports enable reinforced learning

#ISICEM25 | Michael R. Pinsky on Autonomous Diagnosis & Treatment of Circulatory Shock 🚑💡

🔹 The key to precision resuscitation:
•Is the patient in compensated shock?
•Will cardiac output improve with fluids?
•What is the arterial tone status?
•Can the heart sustain output without filling pressures?

#ISICEM25 | Michael Pinsky presents an algorithm for precise personalized resuscitation in shock management 🔄📊

🔹 Stepwise decision-making:
✅ Is the patient hemodynamically stable? If yes, do nothing.
✅ If unstable, assess preload responsiveness.
✅ If preload-responsive, evaluate vasomotor tone

#ISICEM25 | Michael Pinsky on Functional Hemodynamic Monitoring & Closed-Loop Resuscitation 🔄📊

✅ Guided resuscitation with clear decision rules
✅ Standardized yet personalized fluid & vasopressor strategies
✅ Adaptable across ICUs, remote care, and austere environments

Looking at the future!

#ISICEM25 | Lennie Derde on the future of sepsis treatment 🔬🦠

🚀 Moving beyond syndromes to treatable traits
🔹 Reframing immunobiology for better-targeted therapies
🎯 Immune modulation: precision over generalization
🧬 Metabolic reprogramming—a new frontier?

#ISICEM25 | Patricia Rocco on the future of ARDS treatment 🫁🔬

ARDS is heterogeneous, requiring tailored management strategies

#ISICEM25 | @fabio_taccone delivers a brilliantly clear presentation on Automated Pupillometry 👁️💡

"The conclusion is quite simple: If you think measuring pupils makes sense, the pupillometer is better than you!"

🔹 Objective, reproducible, and precise
🔹 Eliminates subjectivity in pupil assessment

#ISICEM25 | Massimiliano Greco on wearable technologies and the future of ICU monitoring! 🚀📡

🔹 Increase mobility & physical therapy
🔹 Reduce invasive devices & sampling
🔹 Improve data visualization & reduce fatigue
🔹 Detect delirium earlier
🔹 Bridge monitoring gaps between ICU & wards

#ISICEM25 | 🚀 The session ‘HOW I IMAGINE THE FUTURE’ is now starting! Moderated by Zsolt Molnar & Christian Stoppe, this session explores bold visions for the future of intensive care.

#ISICEM25 | 🔥 Big debate in the room!

After the first fluid challenge in septic shock, BP rises from 90/40 to 95/45. What’s the next move?

More fluids 💧 or start vasopressors 💉

#ISICEM25 | 🔴 Live from the Arch Room! The Round Table on Early Hemodynamic Resuscitation of Septic Shock is underway.

🗣️ Moderator: Xavier Monnet
💡 Experts: Daniel De Backer, Emily J See, Jean-Louis Teboul, Michelle Chew

#ISICEM25 | Julie Helms explores the role of contact phase activation in bleeding 🩸🔬

#ISICEM25 | Matthieu Schmidt on Setting PEEP in ECMO 🫁🔍

🔹 PEEP helps maintain lung recruitment while reducing driving pressure.
🔹 Personalization is key—balancing overdistension & collapse.
🔹 EIT & transpulmonary pressure can guide adjustments