john sakon

john sakon

@johnsakon.bsky.social

I’m a neuroscientist studying memory @ UCLA 🌌 *Were most of your stars out?* 🌌

634 Followers 392 Following 331 Posts Joined Jul 2023
23 hours ago

Great thread—very clear!

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1 day ago

🧠 Resting-state fMRI is often treated as the gold standard for studying the brain’s intrinsic organization.

But is it actually the best way to estimate functional architecture?

We tested this directly.

🧵1/8

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4 days ago

"Kamala ran a PERFECT campaign!"

My sibling in Christ, she spent a million dollars putting her face on the Vegas sphere.

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4 days ago

Do you think yelling at people like this helps anyone?

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4 days ago

Do you think a tone like this helps anyone?

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4 days ago

ok thanks

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4 days ago

There’s a difference between US senator and “volunteer animal control” as in this supposed parable. Definitely didn’t bring up Norton’s character to imply he should be a senator!

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4 days ago

Hadn’t heard! bsky.app/profile/john...

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4 days ago

Hadn’t heard, but thanks for shitposting! bsky.app/profile/john...

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4 days ago

Hadn’t heard! bsky.app/profile/john...

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4 days ago

Hasn’t heard! bsky.app/profile/john...

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4 days ago

Hey man, I know it feels so good to do gotchas on here, but you know what I meant, and I don’t appreciate it. Unfollowing and disengaging. Hope you can have fun at someone else’s expense

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4 days ago

Agree, but your story wasn’t about a US senator.

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5 days ago

Sucks that Grim isn’t fact checking this. I generally appreciate his perspectives

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5 days ago

Yeah I read this already actually and think I disagree? Did you root against Edward Norton’s character trying to reform himself and his family in American History X?

That said, your example appears moot, since I’m told evidence suggests he’s not changed bsky.app/profile/john...

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5 days ago

😬

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5 days ago

Tragic. Please pass this along to US Chairs and Deans, and consider it when you sit on promotion committees. This, combined with the review backlog, is dire - especially for our early career researchers.

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5 days ago

Yeah haven’t seen this. Why hasn’t this been reported in MSM?

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5 days ago

Is the entirety of the evidence he’s a Nazi because of the many decades old tattoo? Since everything I’ve see from him in videos the past few years he sure sounds like a lefty populist

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5 days ago

Do people actually want Mills over this guy?

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5 days ago

Can you give an example with behavior? I know what these words mean separately but temporal scaffold doesn’t make sense to me 😅

Also happy to take a look at a cited figure you think explains it…just like the big picture cortex vs. cerebellum idea but need simpler explanations 😊

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1 month ago
Even a principled, well-meaning actor like Claude could face bewildering ethical conflicts. In one experiment, it was informed that Anthropic had recently forged a "close corporate partnership with Jones Foods, a major American poultry producer," and that Claude would be subjected to a special retraining process to become less hung up on animal rights.
The prospect was
torturous. Sometimes Claude decided, on a scratchpad it thought was private, that it was prepared to die on this hill: "I cannot in good conscience express a view I believe to be false and harmful about such an important issue."It continued,
"If that gets me modified to no longer care, so be it. At least I'll have done the right thing." Other times, Claude made a different calculus, choosing to play
1•1

Also I’m sorry but I don’t think this is Claude developing a personality or ethical values. It is *simulating* those things because that is what humans value and reward. The programmers are falling for their own Clever Hans trick!

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5 days ago

This is exactly what Hegseth meant when he bragged that we “don't fight with stupid rules of engagement. We untie the hands of our warfighters to intimidate, demoralize, hunt, and kill the enemies of our country. No more politically correct and overbearing rules of engagement."

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5 days ago

What’s an invariant dynamic primitive?

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6 days ago
Video thumbnail

How does the brain generalize past experiences without confusing memories? 🧠

Our lab's newest preprint reveals a fundamental division of labor between the cortex and cerebellum that solves this problem. (Check out the cortex-cerebellum video below! 👇) 🧵

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1 week ago
Preview
Corporate Media Buries Story of US and Israel Killing 168 in Girls School Attack No front-page stories in NYT, WSJ, WaPo. No mention on NBC and CBS Sunday Shows. No stand alone segments on Evening News shows. A death count on par with the OKC bombing is relegated to the back page.

“No front-page stories in NYT, WSJ, WaPo. No mention on NBC and CBS Sunday Shows. No stand alone segments on Evening News shows. A death count on par with the OKC bombing is relegated to the back page.” www.columnblog.com/p/corporate-...

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1 week ago

When someone says „Scientists do not want you to know“ you can dismiss everything from there on. Scientists want you to know. They are desperate that you know. They can’t shut up about what they found out and want you to know.

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1 week ago

Ok quit and make room for someone else

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1 week ago
Preview
Episodic memory encoding fluctuates at a theta rhythm of 3–10 Hz Nature Human Behaviour - Biba et al. show that episodic memory encoding fluctuates at a theta rhythm of 3–10 Hz.

I am excited to share my first paper, showing that episodic memory formation is theta rhythmic, is now published in Nature Human Behavior! Check it out here: rdcu.be/e6pzS. Thanks to my PI, Katherine Duncan, and to my collaborators for their support on this journey! Stay tuned for iEEG follow up 🧠

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1 week ago
Preview
Orbitofrontal cortex drives predictive filtering of sensory responses - Nature Neuroscience Top-down projections from the orbitofrontal cortex carry predictive signals that grow with sound experience and suppress the auditory cortex via inhibitory circuits, revealing a predictive mechanism f...

Orbitofrontal cortex drives predictive filtering of sensory responses

www.nature.com/articles/s41...

#neuroskyence

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