Joanna Smeeton

Joanna Smeeton

@smeetonlab.bsky.social

Assistant Professor @Columbia in NYC. Developmental biologist focused on regeneration research in zebrafish. Rebuilding joint ligaments and cartilage at the Columbia Stem Cell Initiative. All views my own.

2,350 Followers 952 Following 23 Posts Joined Aug 2023
3 weeks ago
News Splash Issue 21 Winter 2026 | IZFS - International Zebrafish Society

The new @IZFS News Splash is out! IZFS.org/newssplash/news-splash-issue-21-winter-2026 . Check it out for a SCZI meeting report, Alternatives to Academia (alliance management), Science Spotlight articles, member news and more!

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1 month ago
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a man in a suit says check this out in yellow letters ALT: a man in a suit says check this out in yellow letters

For #BlackHistoryMonth and International Day of Women and Girls in Science, we wanted to highlight a few organizations you should follow and support! We'll link their websites, be sure to check them out!

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1 month ago
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Thinking about EZM2026 in Vienna? 🐟
Travel grants are now open for students & ECRs.
7–11 July 2026 | Deadline: March 15
Hope to see many of you there! @ezsociety.bsky.social #zebrafish

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3 months ago

Congratulations Dr. Voigt!! 🎉🎉

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4 months ago
An orange sunset over NYC

A gorgeous evening here in NYC

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4 months ago
A group of 8 people dressed as characters from the TV show Avatar: the Last Airbender. A group of 8 people dressed as characters from the TV show Avatar: the Last Airbender.

Working with #zebrafish you might expect us all to be from the Water Tribe, but representatives from all nations of the world of #Avatarthelastairbender turned out to represent the Smeeton lab at our Columbia Stem Cell Hallowe'en party this year!

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4 months ago

Chlorine in the water

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4 months ago
Picture of Perspective title and authors from article PDF

Speaking science in a fractured world: making truth land when facts alone cannot

A Perspective by @rebeccacalisi.bsky.social, @kaliceaphd.bsky.social, Jamy Peng, @spiraldoc.bsky.social & @rogerslabucd.bsky.social on how to combat scientific misinformation

journals.biologists.com/dev/article/...

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5 months ago
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New York Cures – NY-CURESNew York Cures Website NY-CURES is working to advance bold, state-backed investment in biomedical research—on the scale of successful initiatives in California and Texas—to grow New York’s leadership in science, innovation, and health.

The BIGGEST impact you can have with 1 minute today ⏱️

Add your name to show NY is ready for a statewide biomedical institute.

CA’s CIRM & TX’s CPRIT proved it works—billions returned, jobs created, cures accelerated. Let’s do even better for New York.

✍️ www.nycures.org/

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5 months ago
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Dynamic cell fate plasticity and tissue reintegration drive functional adult synovial joint regeneration after complete resection - Nature Communications Joint injury and disease are leading causes of disability, with mammalian joints exhibiting poor regenerative capacity. Here the authors showed that after loss of a whole joint, adult zebrafish regenerate de novo articular cartilage, ligament, and synovium into a complex joint organ.

📣🧪 Read our latest #research on joint regeneration in #zebrafish, published today in @natcomms.nature.com www.nature.com/articles/s41... @columbiauniversity.bsky.social

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5 months ago
A photo of Joanna Smeeton and Troy Anderson. Joanna is pointing to the PhD celebration champagne cork from Troy's defense that he is holding Troy smiling and holding a box after packing up his desk.

🍾🧪The end of an era! Today we said so long to Dr. Troy Anderson. Troy was the very first person to join me in the Smeeton lab. He just defended his PhD and is off to start his postdoc next month. We will miss you Troy!! #proudPI @troy-anderson.bsky.social #zebrafish

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6 months ago
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Register now for an ORS Tendon Section #WebinarWednesday on Sept 24, 12 PM CST, A Tendon-cy to Heal: Regenerating Tendons & Ligaments in Zebrafish. Hear from Thomas Schilling, Jenna Galloway & Joanna Smeeton on the latest #tendon & ligament regeneration. 🔗 ors.memberclicks.net/ten092425web#/

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8 months ago

Thank you Kevin for all that you have done to get our community schooling together online. I really appreciate all your hard work and engaging posts!! See you over on the Slack channel to keep the conversations going.

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9 months ago
Figure taken from MacRae & Peterson (2015): How suitable are zebrafish for discovering human drugs? Although zebrafish enable in vivo studies on a large scale, questions remain about how relevant the findings are for drug discovery. Recent studies have begun to elucidate the degree of conservation between humans and zebrafish, which share 82% of disease-associated targets and a large number of drug metabolism pathways (as illustrated by the mass spectrometry of metabolic by-products). Zebrafish physiology is often well conserved (sometimes more so than rodent physiology); for example, cardiac electrophysiology (illustrative electrocardiogram (ECG) tracings from each organism are shown). Several compounds discovered in zebrafish screens have been shown to exhibit similar effects in rodent models and humans, including eight out of ten compounds tested by our groups. m/z, mass to charge ratio.

Due to their aquatic environment, #zebrafish are perfect for small molecule drug screens. Many drugs have been repurposed for novel treatments such as COX inhibitors in leukemia & glucocorticoids in long QT syndrome. For more, read this Nature review ($): doi.org/10.1038/nrd4... #ZebrafishFunFacts 🧪

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9 months ago
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Revascularization of coronary endothelial cells during zebrafish heart regeneration. Credit to @harrisonlab.bsky.social. #ZebrafishZunday 🧪

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9 months ago
Danio rerio Annotation ReportTwitterFacebookLinkedInGitHubNCBI Insights BlogTwitterFacebookYoutube

Some exciting news! NCBI has finished the annotation pipeline for our new #zebrafish reference sequence GRCz12tu:
www.ncbi.nlm.nih.gov/refseq/annot...

This is a big step up in data depth and quality and should be super helpful going forward.

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10 months ago
News Splash Issue 19 Spring 2025 | IZFS - International Zebrafish Society

We are excited to announce our next issue of #NewsSplash has been published! To keep up with all the latest #zebrafish news, be sure to check it out here: www.izfs.org/newssplash/n...

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11 months ago

Congratulations Olena!!

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11 months ago

Congratulations Peter!!

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11 months ago
Linocut portrait of biochemist and medical researcher Maud Menten (1879-1960) with the Michalis-Menten equation in blue and a histology image in pinks and purples in the background.

Happy birthday to Canadian medical researcher & #biochemist Maud Menten (1879-1960). 🧪🐡👩🏼‍🔬 #histscj Not only was she an author of Michaelis-Menten equation for enzyme kinetics, she invented the azo-dye coupling for alkaline phosphatase, 1st example of enzyme histochemistry, still used in imaging of 🧵

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1 year ago
4 smiling research scientists

Heading back to NYC full of fresh ideas and new questions to explore after a wonderful visit with the fantastic faculty and trainees @cuanschutz.bsky.social Thanks again for the invitation to share our work on craniofacial joint regeneration!

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1 year ago
Abstracts | IZFS

Abstract submissions for the 19th IZFC are now open! Registration to the conference is required to submit an abstract. Register and submit here today! www.izfs.org/education/19...

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1 year ago
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NIH slashes overhead payments for research, sparking outrage and lawsuit Move to cut indirect cost rate to 15% could cost universities billions of dollars

Breaking news: 22 states are suing to block NIH’s cutting of indirect costs.

See our updated story on the Friday night news and its aftermath. scim.ag/4hTJQ6v

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1 year ago

These opening sessions talks were exactly what I needed after the week we have had.

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1 year ago
ORS President at a podium in front of a screen showing the word Community

"We need eachother more than ever before" #ORS2025

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1 year ago
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD

1. Today the NIH director issued a new directive slashing overhead rates to 15%.

I want to provide some context on what that means and why it matters.

grants.nih.gov/grants/guide...

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1 year ago

ZFIN is now on Bluesky!

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1 year ago
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White House pauses all federal grants, sparking confusion The Trump administration has put a hold on all federal financial grants and loans, affecting tens of billions of dollars in payments.

I think some people hear “grants” and think that without them, scientists and government workers just have less stuff to play with at work. But grants fund salaries for students, academics, researchers, and people who work in all areas of public service.

“Pausing” grants means people don’t eat.

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1 year ago
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Our Ears Share a Common Ancestry with Fish Gills The genes that build the cartilage of fish gills were repurposed to build the cartilage in mammals’ outer ears

Nice article in Scientific American about our work on outer ear evolution and a complimentary study from the lab of Maksim Plikus on role of unique lipids in mammalian ear cartilage. www.scientificamerican.com/article/our-...

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1 year ago
Figure 1 (A) Example images illustrating a major delay in initiation of bone mineralization in sox10 mutants between 3 and 7 dpf revealed by Alizarin Red staining. Some mineralization is present by 5 dpf but never achieves control levels before lethality at 8 dpf.

Sox10 is required for systemic initiation of bone mineralization

Read this #OpenAccess Research Article by Stefani Gjorcheska, Lindsey Barske & co. @cincyresearch.bsky.social :
https://journals.biologists.com/dev/article/152/2/dev204357/365396/Sox10-is-required-for-systemic-initiation-of-bone

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