NSB Lab

1000s of studies have been published mapping neuroanatomical changes in psychiatric disorders. Can we ever converge on robust disease phenotypes? Our latest PP led by Trang Cao in a huge collab effort investigates this question...

@nsb-lab.bsky.social

Have you been using ABCD data? Are you measuring psychopathology with the CBCL? You will want to check out our latest preprint, led by @kanepav.bsky.social, which shows that the constructs measured by the tool fail to meet many basic validity tests. Peep the thread!

New preprint out from @kanepav.bsky.social & @nsb-lab.bsky.social challenging the CBCL’s utility as a measure of psychopathology in the ABCD study.

The popular Child Behavior Checklist (CBCL) does NOT meet many crucial psychometric standards! Checkout our latest preprint led by @kanepav.bsky.social and using baseline measurements from the ABCD cohort:

Check out our recent preprint by Trang Cao and a huge team of collaborators, on the inter-site reliability of neuroanatomical alterations in psychiatric disorders! Teaser: cross-site correlations are not very high… 👇

Francis Normand’s talk on linking connectomes and brain geometry happening NOW, room P2 #ohbm2025

Lab alumnus @stuartoldham.bsky.social’s fantastic talk happening now at the great hall !
#OHBM2025

Don’t forget to also checkout Chris Adamson’s work today at Poster 1552, on investigating and improving the accuracy of braincharts calibration of small sample sizes to normative data by using repeated measures !

The final day of #OHBM2025 is here. Let’s finish strong!
🧳 Luggage storage is available today! See picture for details.
Thank you for being part of an incredible week. Safe travels and see you at #OHBM2026!

Ashlea @ashleasegal.bsky.social is doing amazing work as the Chair of the OHBM Student and Postdoc Special Interest Group (SP-SIG), which has also been putting out amazing programming all year long 😍

Holmes Lab is representing at #OHBM2025! 🧵 Loic
@loiclabache.bsky.social presented in the Language: Anatomy, Networks and Pathology section with his paper on "The molecular and cellular underpinnings of human brain lateralization" 🧠

The last poster session is today! 🤩🧠🧬!

Two of the SP-SIG’s Career Development & Mentoring managers have their posters today! Go and check out both Priscilla’s poster #1636 and Katies at #1774!

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#OHBM2025 is here and the champs from @pennlinc.bsky.social have brought their freshest work express from Philly to Brisbane. Thread below . . .please reach out + come say hi -- always looking to talk science + make new friends!!!

Last but not least, lab alumnus Sidhant Chopra will be presenting some amazing work on a super-unique dataset: An antipsychotic-naïve (!!!) cohort of people with psychosis. Checkout his Poster 1696

Interested in individualized parcellations? Come have a look at Priscila Thalenberg Levi's exciting new work on a geometrically-grounded AND individualized eigenmode-based parcellation, Poster 1636 !

Check out Stuart’s great work today and tomorrow!

Have you wondered how multi and single echo fMRI compare, and what denoising pipelines do best? Check Toby Constable's work at Poster 1573, comparing dozens of denoising strategies in terms of data quality and behavioural prediction and finding evidence favouring multi echo acquisitions !

And @m-gajwani.bsky.social's work comparing geometric modes to mouse tract-tracing🐁. Do more invasive tract tracing results (rather than diffusion MRI) improve the performance of connectome eigenmodes?

Find out at Poster 1708

Also check out Victor Barnes' work demonstrating some novel improvements to traditional eigenmode approaches, incorporating regional heterogeneity! (also featuring macaque and marmoset 🐒📷!!) His poster is 1666

If you want to see some of our newest methods and results linking geometric & connectomic features being applied across these species -- check out Francis Normand's Poster 1773 !
He also has an excellent talk in the "Multivariate Approaches...." session (Saturday)

Good morning #ohbm2025! We still have a host of great posters to present over the last two days of the conference so keep your eyes peeled 👀

1573 - #multi-echo #fMRI
1666 - #heterogenous modes
1696 - new #psychosis dataset
1708 - #eigenmodes in #mice
1773 - linking #geometry & #connectome

Details👇

Yinuo Shu will be looking at methodologies for ecological momentary assessments. We have more and more complicated statistical measures that we can use. But how much do they actually add?

Find out at Poster 596 (Wed/Thurs)!

Gabriella Chan will be looking at network changes in schizophrenia. Can grey matter changes in SCZ be modelled using the connectome?

Poster 461 (Wed/Thurs)

@izachpope.bsky.social will be looking at FC changes in the same antipsychotic naïve, first episode psychosis cohort.

Can functional connectivity predict longitudinal clinical outcomes in first-episode psychosis?

Poster 546 (Wed/Thurs)

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@sidchop.bsky.social will be presenting some amazing work on a super-unique dataset:

An antipsychotic-naïve(!) cohort of people with psychosis

Poster 1696 (Fri/Sat)

And he'll also be talking about how to get the most out of your information-dense data in the roundtable on Wed 1245-1345

Nanfang Pan will be showcasing new work using network similarity measures to subtype ADHD!

You can check out his talk in the "Early Life Neurodevelopmental Disorder" session (Thurs 1130)

and at Poster 265 (Wed/Thurs)

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We also have a lot of clinical results to present 🏥

Trang Cao has been using modes to identify group differences. See an example in a cohort of people w schizophrenia:
- Talk in the Neuroimaging Stats Satellite workshop (Mon 9:30-10:45)
- Poster 485 (Wed/Thurs)

And @m-gajwani.bsky.social's work comparing geometric modes to mouse tract-tracing🐁. Do more invasive tract tracing results (rather than diffusion MRI) improve the performance of connectome eigenmodes?

Find out at Poster 1708 (Fri/Sat)!

Also check out Victor Barnes' work demonstrating some novel improvements to traditional eigenmode approaches! (also featuring macaque and marmoset 🐒🤗!!)

His poster is 1666 (Fri/Sat)

You can have a look at Priscila Thalenberg Levi's new work extending the eigenmode-parcellations to individuals!

Poster 1636 (Wed/Thurs)