Alain Dagher

Quebec tables draft constitution to affirm its 'distinct national character,' premier says | CBC News The constitution, filed at the National Assembly on Thursday and lambasted by opposition parties as a piece of political theatre filed without proper consultation, includes language asserting Quebec’s...

Francois Legault and Simon Jolin-Barrette are vying to become the Thomas Jefferson and Benjamin Franklin of Quebec.

www.cbc.ca/news/canada/...

I hate this place.

Estro Vino e Cucina | Cucina Contemporanea Veneziana | Vini Naturali a Venezia Cucina Contemporanea Veneziana e 700+ etichette di vini naturali da tutta Europa. Dario e Alberto Spezzamonte, originari di Murano, guidano rispettivamente sala e cucina.

www.estrovenezia.com/estro/

Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉

📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io

📅 Save the Date: Oxford 2026 Glymphatic Research Symposium!

• Dates: March 30th, March 31st, April 1st 2026.
• Keynote speakers: Maiken Nedergaard & Jonathan Kipnis.
• Venue: Keble College, Oxford, UK.
• Registration link to follow

Looking forward to seeing you there! 🧠

McGill University to open ‘satellite campuses’ outside Canada, president says Deep Saini framed the planned satellite operations as an extension of McGill’s Quebec base, describing the university as “a locally anchored, globally pre-eminent university.”

How can one volunteer?
www.montrealgazette.com/news/provinc...

Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...

How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ⤵️

GitHub - netneurolab/Farahani_ALS: Network spreading and local biological vulnerability in amyotrophic lateral sclerosis Network spreading and local biological vulnerability in amyotrophic lateral sclerosis - netneurolab/Farahani_ALS

Huge thanks to Sanjay Kalra and the CALSNIC team, J Hansen, @vincebaz.bsky.social @goliashf.bsky.social L Collins @dadarmahsa.bsky.social @alaindagher.bsky.social !!

code: github.com/netneurolab/...

The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG...

Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️

New paper in Imaging Neuroscience by Malte R. Güth, Travis E. Baker, et al:

Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation

doi.org/10.1162/IMAG...

This important new study in Movement Disorders looked at folks w/ REM sleep behavior disorder, a common early sign of Parkinson’s. The results suggest that fMRI may reveal changes in brain networks long before symptoms of PD or dementia w/ Lewy bodies fully emerge. @parkinsondotorg.bsky.social

Companies charging and people paying up to $500,000 to select embryos with high IQ potential, even though that isn't possible. No less ethical.
"Current models explain about 5% to 10% of the differences in cognitive ability between people"
Front page WSJ today www.wsj.com/us-news/sili...

2. When I give seminars about this, I ask my (professional scientist) audience "How many of you believe that anthropogenic climate change is real?"

Almost all hands raise.

I then ask "How many of you have read the IPCC report or equivalent"

Fewer than 25% of hands raise.

Separatist group applies to have review of Alberta referendum question quashed | Globalnews.ca A court in Edmonton is being asked Thursday whether a proposed referendum question on Alberta separation would be a violation of the Canadian constitution.

Yesterday I decided to become a Samsung phone user. Today I am a separatist. Never say never! 😀
globalnews.ca/news/1132233...

Normative blood perfusion map on lateral and medial views of the inflated and 2D flat cortical surfaces (fsLR). Borders and areal names of the multi-modal Glasser parcellation are overlaid on the flat surface. The figure highlights the non-uniform distribution of perfusion scores across the cortex, with areas that have sharp gradient compared to their underlying perfusion score levels (e.g., LIPv and MT/MST).

How does cerebral #BloodPerfusion map onto micro-, meso- & macro-scale brain structure? @asafarahani.bsky.social @misicbata.bsky.social &co characterize blood perfusion in the #HumanBrain, revealing how it changes with age & in #NeurodegenerativeDisease @plosbiology.org 🧪 plos.io/46AEURS

Integrating and interpreting brain maps | doi.org/10.1016/j.ti...

Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️

LaSalle College says it helps French thrive, so why is Quebec cracking down on it? Instead of punishing the school, the CAQ government should be using it as a model for francization and the principle of harmonious “vivre ensemble,” the school’s president and CEO says.

"The Quebec government has served the school with fines totalling almost $30 million for violating the province’s language law by admitting too many students to its English-taught continuing-education programs over the last two years."

Read more at: www.montrealgazette.com/news/article...

In collab with @alaindagher.bsky.social @misicbata.bsky.social and Shady Rahayel, we used the SIR model to computationally model neurodegenration as a function of the structural connectome and gene expression. SIR cpatures the dynamics better than axonal connectivity (very bad!) and gene expression!

Linking neuron-axon-synapse architecture to white matter vasculature using high-resolution multimodal MRI in primate brain Abstract. Blood vessels and axons align outside the brain due to shared growth factors. However, this neuron-axon-synapse and vessel relationship within the brain white matter remains unclear, primari...

direct.mit.edu/imag/article...

Energy expenditure and obesity across the economic spectrum | PNAS Global economic development has been associated with an increased prevalence of obesity and related health problems. Increased caloric intake and r...

On the root cause of global obesity
www.pnas.org/doi/suppl/10...
www.science.org/content/arti...
www.washingtonpost.com/wellness/202...

Food Intelligence by Julia Belluz, Kevin Hall, PhD: 9780593332306 | PenguinRandomHouse.com: Books The essential guide for understanding what you’re eating, and the forces that are driving you to eat it. Nutrition isn’t rocket science; it’s harder. There are new diet fads, bold...

Excited to announce my new book FOOD INTELLIGENCE coauthored with brilliant journalist @juliabelluz.bsky.social‬! Cutting through the confusion about diet & health, #FoodIntelligence describes the fascinating science of how food both nourishes & harms us. www.penguinrandomhouse.com/books/671334...

Hi everyone! Blue Sky seems alright!
Check out our massive new review on Coenzyme Q that earned the cover 😉.

ENIGMA is a tremendous achievement ! Congratulations @ptenigma.bsky.social

New paper in Imaging Neuroscience by Stephen M. Smith, Karla L. Miller, and Thomas E. Nichols:

Characterising ongoing brain aging and baseline effects from cross-sectional data

doi.org/10.1162/IMAG...

Does the carbon footprint calculation include travel to hackathons?

In sum, we use genetics to uncover three different facets of impulsivity, each with different genetic and neurodevelopmental associations. Further deciphering the complicated interplay of genetics and environment is an exciting future direction⭐

Finally, we found that each brain measure has a different ratio of genetic vs environmental influences. For example, cortical thickness was better captured by impulsivity PGSs, but surface area was more environmental.

Next: how does environment come into play? We found that Area Deprivation Index modulates the relationship between lack of self-control PGS and white matter. Lower ADI amplified the effect of genetic risk on WM development.

We also tested longitudinal changes in brain anatomy! Lack of self-control PGS was mostly related to slower development of white matter.

We then asked how the polygenic score for each latent factor manifested in the brain using ABCD (9-11 yrs, N>4,000). Lack of self-control: reduced prefrontal GM; reward drive: increased cellularity in subcortical nuclei; sensation seeking: increased surface area and white matter FA.