Alain Dagher's Avatar

Alain Dagher

@alaindagher.bsky.social

Neurology and brain imaging. ORCID: 0000-0002-0945-5779

350 Followers  |  394 Following  |  110 Posts  |  Joined: 11.11.2024  |  2.0208

Latest posts by alaindagher.bsky.social on Bluesky

As an editor for many years, I still believe in the importance of peer review, especially in journals closely linked to specific scientific communities/societies. It's not a guarantee of course.

It's like if you weed your garden regularly. Will you still have weeds? Yes. Does it help? Also yes.

11.12.2025 22:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Brain size links neurodevelopment to neurodegeneration in Parkinson's disease Genetic studies have advanced our understanding of Parkinson's disease (PD) pathogenesis, establishing a role for autophagy and lysosomal dysfunction. However, how genetic risk translates into neurona...

Cortical expansion and genetic risk for PD.
Led by Houman Azizi and Nooshin Abbasi.
With @ptenigma.bsky.social @misicbata.bsky.social @yasharneuro.bsky.social @ndrewvo.bsky.social and many others www.medrxiv.org/content/10.6...

11.12.2025 22:34 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Yes. The ones that were rejectedπŸ˜€

11.12.2025 22:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...

Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism: Neuron www.cell.com/neuron/fullt...

30.11.2025 13:53 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

lol. No one who has done time in Canadian Academia has any illusion that it’s a meritocracy.

22.11.2025 18:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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I asked nano banana in Gemini 3.0 to make a diagram explaining two-sample MR with an arrow indicating pleiotropy. This is what it came up with. Not great - and what on earth is "pleizorotty"?

21.11.2025 14:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Why does your brain shrink in Parkinson’s? Word shrink in this case refers to measurable loss of brain tissue (atrophy), which reflects thinning of cortex/loss of volume in key brain regions. New paper shows widespread atrophy following brain’s wiring diagram and local biological vulnerabilities.

17.11.2025 12:35 β€” πŸ‘ 7    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
Washington Commanders at Miami Dolphins 2025 REG 11 - Game Center | Official Site of the National Football League The official source for NFL news, video highlights, fantasy football, game-day coverage, schedules, stats, scores and more.

Should called it the Siesta Bowl.

www.nfl.com/games/comman...

16.11.2025 15:40 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Obituary – Jonathan Smallwood

Jonny Smallwood @themindwanders.bsky.social was a beloved friend and mentor. He was taken from us too soon. His was a beautiful mind who understood the beauty of minds. As ever before, his kind voice guides me and his work will continue. We miss you Jonny. www.cbs.mpg.de/news/obituar...

13.11.2025 15:19 β€” πŸ‘ 103    πŸ” 31    πŸ’¬ 15    πŸ“Œ 8
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Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...

New paper with @statsepi.bsky.social and @deevybee.bsky.social in which we show there's really no evidence for a link between the gut microbiome and autism www.cell.com/neuron/fullt...

13.11.2025 16:10 β€” πŸ‘ 187    πŸ” 63    πŸ’¬ 6    πŸ“Œ 5
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New paper in Imaging Neuroscience by Ying-Qiu Zheng, Saad Jbabdi, et al:

An image quality transfer approach for localising deep brain stimulation targets

doi.org/10.1162/IMAG...

13.11.2025 21:22 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Happy to share our review "Investigating hierarchical critical periods in human neurodevelopment” in @npp-journal.bsky.social! We examine neurobiological, environmental & behavioral evidence for human critical periods in sensory and association cortex +discuss new research directions rdcu.be/eMkVU 🧡

11.11.2025 20:01 β€” πŸ‘ 91    πŸ” 43    πŸ’¬ 4    πŸ“Œ 3

I agree - I would see talented recruits as potential collaborators, not competitors.

05.11.2025 16:36 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Quebec minister steps down day after daughter criticizes special law for doctors | CBC News Social Services Minister Lionel Carmant has announced he is leaving his position in the CAQ government.

But now it seems he's found his moral centre www.cbc.ca/news/canada/...

31.10.2025 17:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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CAQ vs. English universities: FranΓ§ois Legault's specialty is cutting Quebec off at the knees FranΓ§ois Legault’s decision to double the cost of university tuition for out of province students is shortsighted, mean-spirited and, from an economic vantage point, completely idiotic.

And when they came after English universities, Lionel Carmant said nothing because his daughter was not at an English university cultmtl.com/2023/10/caq-...

31.10.2025 17:30 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Quebec bill would extend religious symbols ban to school support workers, force students to uncover faces | CBC News The Quebec government is putting forward a bill that would extend the province's ban on the wearing of religious symbols to support staff in schools, and prohibit studentsΒ from having their faces cove...

When they came after young women wearing a hijab, Lionel Carmant said nothing because his daughter does not wear a hijab. www.cbc.ca/news/canada/...

31.10.2025 17:30 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Multiplex immunofluorescence of AΞ² species

Multiplex immunofluorescence of AΞ² species

🚨New in Lancet Neurology: Autopsy study of aducanumab in #Alzheimer’s shows superficial cortical AΞ² cleared, but deeper persists. ARIA showed inflammation+ microinfarcts in leptomeningeal/penetrating vessels. Some path is PET-invisible. @drneurochic.bsky.social
authors.elsevier.com/a/1lxn85FFzL...

16.10.2025 10:33 β€” πŸ‘ 14    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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I have really enjoyed this book.

16.10.2025 18:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Your Genes Are Simply Not Enough to Explain How Smart You Are Seven years ago, I took a bet with Charles Murray about whether we’d basically understand the genetics of intelligence by now.

In 2018, Charles Murray challenged me to a bet: "We will understand IQ geneticallyβ€”I think most of the picture will have been filled in by 2025β€”there will still be blanksβ€”but we’ll know basically what’s going on." It's now 2025, and I claim a win. I write about it in The Atlantic.

13.10.2025 13:33 β€” πŸ‘ 348    πŸ” 125    πŸ’¬ 11    πŸ“Œ 18
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Quebec tables draft constitution to affirm its 'distinct national character,' premier says | CBC News The constitution, filed at the National Assembly on Thursday and lambasted by opposition parties as a piece of political theatre filed without proper consultation, includes language asserting Quebec’s...

Francois Legault and Simon Jolin-Barrette are vying to become the Thomas Jefferson and Benjamin Franklin of Quebec.

www.cbc.ca/news/canada/...

10.10.2025 13:24 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I hate this place.

08.10.2025 20:39 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Estro Vino e Cucina | Cucina Contemporanea Veneziana | Vini Naturali a Venezia Cucina Contemporanea Veneziana e 700+ etichette di vini naturali da tutta Europa. Dario e Alberto Spezzamonte, originari di Murano, guidano rispettivamente sala e cucina.

www.estrovenezia.com/estro/

07.10.2025 22:21 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! πŸŽ‰

πŸ“š Read the paper: authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset: reprobrainchart.github.io

22.09.2025 21:51 β€” πŸ‘ 71    πŸ” 39    πŸ’¬ 3    πŸ“Œ 2

πŸ“… Save the Date: Oxford 2026 Glymphatic Research Symposium!

β€’ Dates: March 30th, March 31st, April 1st 2026.
β€’ Keynote speakers: Maiken Nedergaard & Jonathan Kipnis.
β€’ Venue: Keble College, Oxford, UK.
β€’ Registration link to follow

Looking forward to seeing you there! 🧠

12.09.2025 14:59 β€” πŸ‘ 7    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
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McGill University to open β€˜satellite campuses’ outside Canada, president says Deep Saini framed the planned satellite operations as an extension of McGill’s Quebec base, describing the university as β€œa locally anchored, globally pre-eminent university.”

How can one volunteer?
www.montrealgazette.com/news/provinc...

17.09.2025 23:30 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Network spreading and local biological vulnerability in amyotrophic lateral sclerosis |
doi.org/10.1038/s420...

How do brain network structure and local biological features shape the spatial patterning of atrophy in ALS? @asafarahani.bsky.social investigates ‡️

16.09.2025 16:16 β€” πŸ‘ 22    πŸ” 16    πŸ’¬ 1    πŸ“Œ 0
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GitHub - netneurolab/Farahani_ALS: Network spreading and local biological vulnerability in amyotrophic lateral sclerosis Network spreading and local biological vulnerability in amyotrophic lateral sclerosis - netneurolab/Farahani_ALS

Huge thanks to Sanjay Kalra and the CALSNIC team, J Hansen, @vincebaz.bsky.social @goliashf.bsky.social L Collins @dadarmahsa.bsky.social @alaindagher.bsky.social !!

code: github.com/netneurolab/...

16.09.2025 16:16 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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The effect of spherical projections on spin tests for brain maps | doi.org/10.1162/IMAG...

Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ‡️

10.09.2025 13:06 β€” πŸ‘ 25    πŸ” 14    πŸ’¬ 1    πŸ“Œ 1
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New paper in Imaging Neuroscience by Malte R. GΓΌth, Travis E. Baker, et al:

Right posterior theta reflects human parahippocampal phase resetting by salient cues during goal-directed navigation

doi.org/10.1162/IMAG...

10.09.2025 05:41 β€” πŸ‘ 13    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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This important new study in Movement Disorders looked at folks w/ REM sleep behavior disorder, a common early sign of Parkinson’s. The results suggest that fMRI may reveal changes in brain networks long before symptoms of PD or dementia w/ Lewy bodies fully emerge. @parkinsondotorg.bsky.social

04.09.2025 11:43 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

@alaindagher is following 20 prominent accounts