‘New reality’ as world reaches first climate tipping point Researchers in Leeds have joined experts from across the world in warning that Earth is reaching the first of many climate tipping points that will cause catastrophic harm without urgent action.

Researchers in Leeds have joined experts from across the world in warning that Earth is reaching the first of many climate tipping points that will cause catastrophic harm without urgent action.
#climatecrisis #tippingpoint #auspol www.leeds.ac.uk/news/article...

Nominate an outstanding mid-career scientist for the prestigious GSA Medal today. This award honors impactful contributions to genetics and dedication to advancing the community. Nominations close October 1!

🔗 buff.ly/YwPhnVq

BSRA Online Public Seminar Series - BSRA In our new Understanding Ageing: Meet the Scientists series, we’ve invited experts in their field to talk about their research and what it means for each of us as we get older. You don’t need any scie...

Please help spread the word about our inaugural public lecture on Wednesday. Sign up and if you are in the ageing field it’s a great opp for your family to finally understand what you do! 😀
Thanks for your support 🙏

bsra.org.uk/events/bsra-...

C. elegans Biology: IV LAWM This EMBO Workshop on C. elegans Biology is t he IV Latin American Worm Meeting. It will convene in Mérida, Mexico. The overall mission of this meeting is to create an inclusive environment that pro…

Learn all things C. elegans #research at the EMBO | The Company of Biologists Workshop "C. elegans Biology: IV LAWM" in Merida, Mexico, 24–28 February 2026.

Registration by 16 January 2026
Abstract submission by 17 October 2025

meetings.embo.org/event/26-worm
#EMBOWorms2026 #EMBOevents 🧪

🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.

Exciting news📣: #ProteostasisUK is hiring a network manager to help drive an ambitious, #BBSRC funded initiative connecting and expanding #Proteostasis research across the UK. Position initially for 3 years. Deadline September 28th. More info: tinyurl.com/f83rp673 & proteostasisuk.co.uk Please RT

The Vienna BioCenter PhD program in Molecular BioSciences will offer 20+ fully-funded positions in the Autumn Call which is now open. Please share. Further details: www.vbcphd.at

Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!

Beautiful work revealing functional chaperone condensates in the ER.

A chaperone-proteasome-based fragmentation machinery is essential for aggrephagy - Nature Cell Biology Mauthe et al. find that protein aggregate clearance requires fragmentation of the aggregate by a chaperone module and a proteasomal regulatory particle for recruitment and clustering of selective auto...

💫NEW: Mauthe et al. find that protein aggregate clearance requires fragmentation of the aggregate by a chaperone module and a proteasomal regulatory particle for recruitment and clustering of selective #autophagy receptors to initiate phagophore formation.
bit.ly/3JJeJPp

Will you be at the @bsrageing.bsky.social ‪#BSRA2025 this week? Look out for Institute contributions:
- @martint-babraham.bsky.social: RNA binding proteins in Tregs (Friday)
- Rahul Samant: proteostasis strategies, stress resilience & senescence (Friday)
- Institute facilities showcase

Exciting news📣: #ProteostasisUK is hiring a network manager to help drive an ambitious, #BBSRC funded initiative connecting and expanding #Proteostasis research across the UK. Position initially for 3 years. Deadline September 28th. More info: tinyurl.com/f83rp673 & proteostasisuk.co.uk Please RT

VACANCY - We’re recruiting for a visionary group leader to lead fundamental research on Discovery Plant Science as part of our vibrant research community

Successful candidate will be offered a six-year tenure-track position with the opportunity to apply for tenure:

www.jic.ac.uk/vacancies/gr...

🚨 Deadline for nominations extended! 🚨

You have one week to nominate someone doing exceptional neuroscience work! 🧠

Whether they’re in the lab, behind the scenes, or amplifying science through communication—nominate them now before the window closes 👩‍🔬 👨‍🔬

Abstract background representing network connections. Text reads: News - UK Proteostasis Network receives BBSRC Network Grant.

Exciting news for @ukproteostasis.bsky.social and for #proteostasis researchers across the UK! Funding from BBSRC will support the development of the UK Proteostasis network, including:
- connecting & building the community to accelerate research
- supporting ECRs

www.babraham.ac.uk/news/2025/07...

📣Exciting opportunity at @maxperutzlabs.bsky.social 👇
A great chance to join an outstanding research environment, based at campus @viennabiocenter.bsky.social Spread the word or apply!
🆕 #professorship #Professur
🔗 www.maxperutzlabs.ac.at/fileadmin/us...

#bioscifacjobs

We are excited to announce the 11th International Symposium on Autophagy! Deadline for abstraction submission is July 18th, 2025. For more information and registration, please follow this link: www.isa11.org

Speaker opportunities are available for early career researchers and PhD students!

Programme Leader Track - MRC Laboratory of Medical Sciences We are recruiting Programme Leader Track positions focusing on 1) Metabolic Physiology using murine and/or human in vivo models and 2) Immunometabolism.

We're recruiting junior team leaders @mrc-lms.bsky.social This time we're looking for those working in human metabolic disease.

It's a great place to start your lab. Fantastic colleagues, exciting science, world class facilities. Join us!

lms.mrc.ac.uk/work/vacanci...

C. elegans pharynx

Award winning photo from Pavi, our current RA who is leaving to start her PhD.

Look out for a Babraham double billing as you plan your schedule for #SEBconference. @delladavid-lab.bsky.social will join @ukproteostasis.bsky.social members in the proteostasis session on day 1, followed by @drsimoncook.bsky.social in the same slot on day 2.

We are hiring a research assistant 👉 tinyurl.com/yxebtjbj to join our lab working on healthy #ageing and protein #aggregation in C. elegans 🪱. Deadline August 4th. 🙏 RT. #proteostasis @babrahaminst.bsky.social

This is how to have difficult conversations with vaccine sceptics

Thrilled to share our new study:

“A lysosomal surveillance response to stress extends healthspan”

Knockdown of vha-6 in C. elegans activates LySR—a protective program that boosts lysosomal activity, clears aggregates, and extends lifespan.

www.nature.com/articles/s41...

#lysosomes #LySR #aging

Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy RNA splicing enables the functional adaptation of cells to changing contexts. Impaired splicing has been associated with diseases, including retinitis pigmentosa, but the underlying molecular mechanis...

It is finally out! My first Science paper is online and it does not seem real😃. I am Incredibly happy! Really thanks to all my coauthors and special mention to my incredible supervisor Ivan Dikic for all the support and trust ! 🫶. #RNA #Proteostasis #ubiquitin #autophagy #RP
doi.org/10.1126/scie...

The maintenance of oocytes in the mammalian ovary involves extreme protein longevity - Nature Cell Biology Harasimov, Gorry, Welp, Penir, Horokhovskyi et al. analyse proteostasis in mammalian oocytes and ovaries: the maintenance of oocytes involves exceptional protein longevity, and many of the extremely l...

#NCB2024
In June, Schuh & co analyzed #proteostasis in mammalian #oocytes and ovaries: found that the maintenance of oocytes involves exceptional protein #longevity, and many of the extremely long-lived proteins decline as the ovary ages.
www.nature.com/articles/s41...

Cancers adapt to their mutational load by buffering protein misfolding stress High mutational load tumors mitigate effects from protein-damaging mutations by up-regulating complexes that buffer against misfolding stress, revealing therapeutic vulnerabilities and suggesting disr...

#proteostasis
doi.org/10.7554/eLif...
a protein misfolding buffer in cancer cells .... very very cool story

Fellowships, grants and career support – Postdoctoral Fellowships – EMBO Supporting internationally mobile postdoctoral researchers in Europe and around the world

Looking for a #LifeSciences postdoctoral #opportunity? 🧪 Have a look at the EMBO Postdoctoral Fellowships for internationally mobile scientists in #Europe and globally.

Apply before 11 July: www.embo.org/funding/fell...
#research #funding #postdoc

Assistant Professor in Cell and Molecular Biology Join a global community of excellence Karolinska Institutet, Department of Cell and Molecular Biology Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Insti

The Karolinska Institute announces 20 positions for Assistant Professors for outstanding early-career researchers. Positions include a startup package. Application deadline September 2nd. ki.varbi.com/en/what:job/...