Grateful to @ANRFIndia Swarnajayanti and MoE STARS and @iiserkol for funding. Spearheaded by @surashreegoswami.bsky.social and great team work by @soumiliroy.bsky.social @SwagataDas66355 kinetic modelling Indrani from Chetan Gadgil laboratory @csir_ncl

Just out @cellpress.bsky.social Chem our work on antagonistic self-replicators that can leverage their intrinsic catalytic potential to enable selection exclusively out-of-equilibrium. #systemschem @iiserkol @dcsiiserkol authors.elsevier.com/a/1mgR78jWHE...

🧬 A gentler way to pump blood for life support!

We report a new approach to blood pumping for ECMO (extracorporeal membrane oxygenation) that uses magnetic liquid interfaces instead of solid mechanical parts to move blood.

Truly humbled and honoured to receive this from the Honourable President of India at Rashtrapatibhavn grateful to @iiserkol @dcsiiserkol see our discoveries at ddaslab.com

Freshly minted, fiercely brilliant!! Architects of our Systems Chemistry Lab; the 6th, 7th, and 8th PhD! ddaslab.com
IISER Kolkata

Glad to hear this Max!

Our latest work in @jacs.acspublications.org!
Artificial system that can sense, grow, and adapt—just like cells! Our #droplets form directional filopodia in response to chemical cues- a step toward life-like materials. #SoftMatter #MatterToLife
🔗https://pubs.acs.org/doi/10.1021/jacs.5c11719

Non-equilibrium demixing and dissolution of chiral coacervates via intrinsic catalysis Nature Communications - Constructing synthetic mimics of membraneless organelles using small molecules can contribute towards our understanding of active phase separation and their role in the...

Lighting up this Diwali, just out @natcomms.nature.com non-equilibrium demixing & dissolution of chiral coacervates via intrinsic catalysis rdcu.be/eL8mo
#SystemsChemistry, #NonEquilibrium, #LifeLikeSystems, #LLPS
Grateful @IISERKolkata, @ANRF_India Swarnajayanti Award @DBTIndia

Non-equilibrium autopoietic vesicles driven by intrinsic catalysis Complexity in living organism thrives on emergent functions operating far from equilibrium. Here, we show the spontaneous generation of vesicles via self-assembly of bolaamphiphile building blocks accessed from the condensation of a dipeptide and an ester. These vesicles acquire catalytic capability and establish a chemical reaction network to self-sustain under non-equilibrium conditions. This work can offer significant insights for developing life-inspired materials capable of functioning autonomously.

Online now: Non-equilibrium autopoietic vesicles driven by intrinsic catalysis

Glad to be part of this exciting research project. Thanks to @ddaslab.bsky.social @chem @iiserkol
This study shows how simple molecules can create dynamic compartments using feedback-controlled autopoietic behaviour.
Please keep an eye out for more interesting findings from the group!

thankful to @ANRF @Swaranajayanti MoESTARS for funds Shout out to @Sangam @soumiliroy.bsky.social @antarareja.bsky.social @lisa Roy and team!!

Just out Chem ‪@cp-chem.bsky.social‬ on autopoietic out-of-equilibrium vesicles via simple building blocks utilizing dynamic covalent & thermodynamically activated bonds. authors.elsevier.com/a/1lJag8jWHE... #systemschem @iiserkol @dcsiiserkol

Catalytically Active Coacervates Sustained Out‐of‐Equilibrium Our findings demonstrate that simple building blocks can access active condensates by exploiting their own catalytic prowess that eventually helps in the realization of an out-of-equilibrium spatiall...

here is the link onlinelibrary.wiley.com/doi/10.1002/...

Minimal catalytic dissipative assemblies via cooperation of an amino acid, a nucleobase precursor and a cofactor Functions arising from cooperation between protobiopolymers have fueled the chemical emergence of living matter, which requires a continuous supply of energy to exist in a far-from-equilibrium state. ...

Here is the link doi.org/10.1039/D5SC00827A

Just out @chemicalscience.rsc.org
minimal catalytic dissipative-assembly can emerge from an amino acid, nucleobase precursor & a cofactor pubs.rsc.org/.../articlel...
Shout out to Pavel Soumili Pratip & Lisa & Ajeet for DFT suppor.t Thanks IISERKol Swarnajayanti @ANRF MoE-STARs #systemschemistry

Just out @angewandtechemie.bsky.social
We show minimal peptide-based catalytic coacervates can be sustained out-of-equilibrium onlinelibrary.wiley.com/.../10.1002/... Shout out Subhajit, Saurabh, Chiranjit IISER Kolkata Swarnajayanti ANRF DBT #LLPS #condensates
#systemschemistry #reactionnetwork

Life is not based on specific material ingredients since there is a constant turnover of the constituent parts. Rather, it is based on functional behavior. Irrespective of the material composition, if we can replicate the essential functions, we have life!

We have 3 openings for ambitious postdocs or PhD students in our #CDlab - for exciting single-molecule biophysics research on nuclear pores, peroxisomes, or archaeal divisomes.

Check it out and apply: ceesdekkerlab.nl/come-join-us/

RT=nice!

We have a PhD position on reaction networks driven by aminoacyl phosphate esters funded from @ercresearch.bsky.social at @uni-freiburg.de.
Deadline for application is 20/03/25. More information can be found here: static1.squarespace.com/static/5fc39...

Looking for a stimulating conference on physical-organic chemistry ? We are organizing the 20th edition of ESOR from 9-12 September 2025 in Padova, Italy. Visit www.esor2025.com for info. Follow us on @esor2025.bsky.social to stay informed. #Chemsky. Reposts appreciated.

A long hard day. Some laughs, some tears, some Burns, and lots of stories shared. Plenty of toasts at dinner this evening. Goodbye Fraser, sleep well.

Thank you Andreas, for the fantastic talk and for taking the time to visit us @iiserkol