Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
📸 No one follows more etiquette rules than the Royal Family—but notice how King Charles didn’t make any smart-ass or demeaning comments about Zelensky’s attire today.
Why? Because respect isn’t about clothes—it’s about character. And that’s something money can’t buy.
Want to know what we do at our startup Deep Piction? Check out our paper with Denali Therapeutics. Using our proprietary clearing & imaging technologies, we mapped the full targeting profile of brain-penetrating transport vehicles (ATVs) in whole mouse bodies and monkey brains. go.nature.com/3Xifva2
2/ The relative scarcity of interactions between dormant disseminated tumor cells (DTC) and antigen specific T-cells explains immune evasion for metastasis! The authors reveal immune-strategies to overcome this for DTC eradication.
Cyrus Ghajar @fredhutch.bsky.social
www.cell.com/cancer-cell/...
We got a message from the university to remove any use of the "DEI", "diversity", "equity", or "inclusion" from all public-facing documents. They said that even "biodiversity" is being flagged by the federal government. We live in the dumbest timeline.
Deep visual multi-omics profiling reveals mechanisms that underly cancer cell differentiation and aggressiveness in clear cell renal cell carcinoma https://www.biorxiv.org/content/10.1101/2025.01.31.635927v1
A new generation of cancer-preventing vaccines could wipe out tumors before they form.
Learn more on #WorldCancerDay: https://scim.ag/4gk8Qmo
New Paper Online:
Nature-inspired platform nanotechnology for RNA delivery to myeloid cells and their bone marrow progenitors.
www.nature.com/articles/s41...
#Apolipoprotein #Nanotechnology #RNA
A human metabolic map of pharmacological perturbations reveals drug modes of action - @zampierilab.bsky.social @depbiomedicine.bsky.social go.nature.com/3CreANg
See our recent @naturebiotech.bsky.social study SCP-Nano in flow! Mapping LNPs, AAVs, and DNA nanostructures to track targeting & unseen toxicity before clinical trials 🤩. Already >190K access, the most in recent years! 👇🏼 www.nature.com/articles/s41...
Spatial-Mux-seq is a multimodal spatial platform for simultaneously profiling the transcriptome, chromatin accessibility, histone modifications, and select proteins.
www.nature.com/articles/s41...
DeepSeek, a Chinese #AI firm and family of large language models, says it has found a way to match the performance of its U.S. rivals using second-tier graphics processing units—and at a fraction of the cost. scim.ag/4jqcFcF
#NieWiederIstJetzt
Some good news
As of today, the main finding of my PhD is published in the European Journal for Neuroscience! 🥳🥳
Together with Gesine Müller, we looked at hemispheric asymmetries in the mouse auditory cortex. We find layer, sex, and hemispheric differences: doi.org/10.1111/ejn....
🧵
Nature research paper: Targeting FOXM1 condensates reduces breast tumour growth and metastasis
https://go.nature.com/4g7BNC8
Congrats!🎉🥳
Excited to share our new technique for visualizing nanoparticles or viruses at single-cell resolution across the entire mouse body! This approach uses deep learning for precise quantification, and we’ve made the code available-give it a try with your dataset! Thanks so much to the whole team!
Twitter:
LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we developed SCP-Nano: an AI and tissue-clearing-based technology for precision nanotechnology. www.nature.com/articles/s41...
Unraveling the Phenotype of Dormant Metastases Controlled by the Immune System https://www.biorxiv.org/content/10.1101/2024.12.02.626440v1
SCP-Nano: #PrecisionMedicine with Nanocarrier Visualization
Combining advanced imaging & AI, researchers at #HelmholtzMunich, LMU& TUM developed SCP-Nano, mapping nanocarriers in the body at single-cell resolution – offering more precise therapies.
👉https://t1p.de/muluc
"propaganda by Trump’s allies to shift blame to scientists for his administration's disastrous handling of the COVID pandemic that killed 1.2M Americans..worked on some Republican voters" www.scientificamerican.com/article/the-...
Do you have a favorite proteomic paper of 2024? I narrowed my list down to 20-ish. (It's pretty clear what Nature had a favorite) proteomicsnews.blogspot.com/2024/12/my-f...
Great start to 2025. Tumor hypoxia promotes immune evasion by autophagy-mediated downregulation of MHC class I expression leading to reduced antigen presentation. Great work from @halaestephan.bsky.social www.embopress.org/doi/full/10....
Were the cardiac metastases you found proliferative or non-proliferative? Thank you and happy New Year!
In www.biorxiv.org/content/10.1... we propose that #KRAS #dosage integrates signaling & transcription to regulate cell states, driving #heterogeneity, progression & #metastasis
Quantitative Site-Specific Glycoproteomics Reveals Glyco-Signatures for Breast Cancer Diagnosis #AC pubs.acs.org/doi/10.1021/...
