Robert Jansen

Acidic pH Restricts Non‐Tuberculous Mycobacteria Replication Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic ...

Very happy to see this out! Great work by @lockwop.bsky.social @crick.ac.uk and first paper on NTMs from the lab! Parise made a set of 12 fluorescently labelled NTMs covering environmental and opportunistic mycobacteria...
onlinelibrary.wiley.com/doi/10.1111/...

Subsidy for research using microorganisms to recycle critical metals | Radboud University Microbiologist Martyna Glodowska is working on a way to recover critical metals from waste materials such as e-waste, by using the power of microorganisms and biogeochemical processes.

An international team of researchers led by microbiologist Martyna Glodowska will use microorganisms to recover scarce metals from electronic waste. 🦠 The research team is receiving a grant of up to €1.5 million from the SPRIND Tech Metal Transformation Challenge. Read more www.ru.nl/en/research/...

#postdoc #job Environ Analytical Chemistry & Toxicology of #benthic #cyanobacteria @eawag.bsky.social Eawag in #Switzerland! Creating knowledge base of benthic cyanobacteria in Switzerland in collaboration with Pilar Junier Uni.Neuchatel. apply by April 8th.
apply.refline.ch/673277/1346/...

Pls re-post: My department @oxfordbiochemistry.bsky.social are recruiting for several new faculty positions (links below). Broad search in molecular biology/biochemistry, across prokaryotes and eukaryotes. Interested in understanding life at the molecular level, this job might be for you!
1/n

The metabolome of an E. coli CRISPRi library identifies benefits of minimal metabolite levels and targets for engineering Rapp et al. combine genome-scale CRISPRi and metabolomics in E. coli. CRISPRi of enzymes enforces metabolite accumulation, which leads to regulatory crosstalk and side reactions. This suggests that ma...

Technically this required metabolomics on ~3,000 samples from an arrayed CRISPRi library.

The bottleneck wasn’t MS or sampling.

It was sequencing the strains after arraying.

Paper: www.cell.com/cell-systems...

We are searching for a tenure-track junior faculty member. Join our collaborative research environment in the Department of Microbiology and Immunology at WCM. Please see the link to the job posting and distribute among your networks!
apply.interfolio.com/181869

🚀 #ESM2026 registration is open! 46th Annual Congress of the European Society of Mycobacteriology.
📍 Verona, Italy | 🗓️ 22–25 June 2026
🔗 www.esmycobacteriology.eu/event-home

Four more days left to apply or share with your network.

For the 2 postdoc offers in experimental evolution, apply here: fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

For the 2 PhD offers in electromicrobiology, apply here: fa-eosd-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candid...

A novel North Sea ammonia-oxidizing archaeon Nitrosarchaeum marinum leverages a high abundance of transport systems to grow over a wide salinity range Isolation and characterization of a novel North Sea ammonia oxidizing archaeon, Nitrosarchaeum marinum T12, reveals an adaptation to a broad salinity under

Long in the making, great to see the study on line at @femsmicro.org A novel North Sea ammonia-oxidizing archaeon Nitrosarchaeum marinum leverages a high abundance of transport systems to grow over a wide salinity range. #microbiology @ribesresearch.bsky.social academic.oup.com/femsec/artic...

And The Microbes

OH MY GOSH I JUST FOUND THIS 😃

www.andthemicrobes.org

#comic #bacteria #phage #plasmids 🦠

PhD candidate in Equine Intestinal Microbiome and Resistome Join this PhD project to study how the equine gut microbiome and resistome can improve gastrointestinal health and combat antimicrobial resistance.

Our faculty has a particularly interesting PhD position open on antimicrobial resistance, effects of antibiotics treatment on the microbiome and resistome, restoration of the equine microbiome using FMT.

www.uu.nl/en/organisat...

Please contact Mathijs Theelen, email address in the link below.

Beautiful and solid work on trehalose monomycolate synthesis in mycobacteria by @figlegend.bsky.social lab. Check it out folks. Also, for the non-enzymologists, product inhibition is a thing, and actually does matter. 😜

www.pnas.org/doi/10.1073/...

There are just a few days left to apply. #Tuberculosis 🧪🦠 #TBDrugDiscovery

Two postdoctoral positions (3-year) in Experimental Evolution of Methanogenic Microbiomes in Bioelectrochemical Systems Application deadline: 4 March 2026 at 23:59 hours local Danish time

Hiring: two 3-year Postdoc positions

We’re looking for postdocs who can design and run directed laboratory evolution experiments in microbial communities under electrochemical stimulation, and link adaptations to performance using shotgun meta-omics.

Cell-free genomics reveals fundamental regulatory principles of the Mycobacterium tuberculosis transcription cycle Tiers of gene regulation govern cellular life. The intrinsic activities of RNA polymerase (RNAP) constitute a primary tier, while direct modulation by…

Congrats Ruby, Bob, Liz, and team! www.sciencedirect.com/science/arti...

Finally out in @nature.com: a new piece of the puzzle of how complex life evolved. Lead by @archaeal.bsky.social & @katyappler.bsky.social. Great collab with @greening.bsky.social and @kassipan.bsky.social. More pieces to follow soon! www.nature.com/articles/s41...

Meer dan mooie woorden: de universiteit heeft een strategie nodig met radicaal vertrouwen en een biologisch fundament - Vox magazine OPINIE - De nieuwe strategie van de Radboud Universiteit ontvouwt zich als een gedurfde visie die de traditionele bescheidenheid van zich afschudt, schrijft hoogleraar microbiologie Mike Jetten. Maar ...

OPINIE - De nieuwe strategie van RU is een gedurfde visie die de bescheidenheid van zich afschudt, schrijft Mike Jetten : 'we kunnen het ons niet veroorloven een generatie briljante talenten te verliezen omdat ze te uitgeput zijn door bureaucratie & gebrek aan budgetten www.voxweb.nl/opinie/meer-...

📢 4-year PhD position in my lab at @crick.ac.uk

Using active learning & chemical genomics to find new antibiotics with new targets in pathogenic bacteria.

Looking for: chemistry / chem bio / comp bio / micro backgrounds with coding interest.

Deadline 17 March.

www.crick.ac.uk/careers-stud...

14 more days left to apply for these two PhD positions in my team. Please share with your network!

Navigating the conjugated metabolome https://www.biorxiv.org/content/10.64898/2026.02.06.704496v1

ChemEmbed: a deep learning framework for metabolite identification using enhanced MS/MS data and multidimensional molecular embeddings Abstract. Machine learning offers a promising path to annotating the large number of unidentified MS/MS spectra in metabolomics, addressing the limited cov

ChemEmbed: a deep learning framework for metabolite identification using enhanced MS/MS data and multidimensional molecular embeddings url: academic.oup.com/bib/article/...

Membrane-associated effluxosomes coordinate multi-metal resistance in Mycobacterium tuberculosis - The EMBO Journal Bacterial pathogens must withstand metal-induced stress during infection, yet the mechanisms by which they sense and respond to toxic metal ions remain incompletely understood. Here, we uncover a prev...

🎉 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐩𝐮𝐛𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐓𝐡𝐞 𝐄𝐌𝐁𝐎 𝐉𝐨𝐮𝐫𝐧𝐚𝐥!

After 8 months of revision, our work is now online: shorturl.at/WHmFq

We uncover a previously unrecognized way that 𝑀𝑦𝑐𝑜𝑏𝑎𝑐𝑡𝑒𝑟𝑖𝑢𝑚 𝑡𝑢𝑏𝑒𝑟𝑐𝑢𝑙𝑜𝑠𝑖𝑠 survives toxic metal stress during infection.
...

🚨 New preprint!

Together with @carobarisch.bsky.social lab, we investigated how intracellular compartmentalization shapes lipid acquisition in mycobacteria

Interestingly, deleting one FACL enzyme (FACL6) revealed striking compartment-dependent phenotypes 🔬

Check it out: doi.org/10.64898/202...

Beautiful and extensive work from the @carobarisch.bsky.social and @soldatilab.bsky.social labs demonstrating that nutrient utilization in intracellular mycobacteria is dependent on their intracellular location.

Visionary work!!

www.biorxiv.org/content/10.6...

Two more weeks to apply - come join us () in The Netherlands as a postdoctoral researcher on large-scale metagenomic exploration of new lineages!

I am super excited that our paper on inter-laboratory comparability of non-targeted LC–MS/MS analysis of dissolved organic matter was just published in ES&T.

pubs.acs.org/doi/10.1021/...

Unveiling Immune System Perturbations in Early Development Through Zebrafish Models of NADHX Repair Deficiency The vital cofactors NADH and NADPH are prone to hydration, forming hydroxylated redox-inactive derivatives (NADHX and NADPHX) in cells. These damaged metabolites are repaired by two highly conserved ...

doi.org/10.1002/jimd...

Mapping of the viral shunt across widespread coccolithophore blooms using metabolic biomarkers | PNAS The viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events ...

🌊Paper announcement! 📣
Viral infections rewire the metabolic makeup of their host and thereby create distinct chemical signatures. Can we use metabolic biomarkers to diagnose infections of algal blooms in the ocean?
Well, take a look at our new article led by Conny Kuhlisch in @pnas.org
>>

Two fully funded PhD candidate positions in Electromicrobiology (3 years) Application deadline: 4 March 2026 at 23:59 hours local Danish time

In addition to the 2 postdoc jobs posted yesterday, we’re recruiting 2 PhD students (environmental microbiology/ molecular ecology) to join us from April. The projects will map microbial populations across niches in bioelectrochemical systems relevant to biomethanation & link them to performance.