George Goodwin (@gg9761) — Bluesky Profile

1 week ago

@arthritisaction.org.uk @arthritisuk.bsky.social @wolfsonsparc.bsky.social @kingsioppn.bsky.social #PPI #Arthritispain #painresearch

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1 week ago

Microsoft Forms

🦴 Living with arthritis pain?

We’re starting a new project on arthritis pain and want to learn from your experience.

👉 Which movements trigger or worsen your pain?

Please take a few minutes to complete our short survey:
forms.office.com/e/qv0tx9LJ1L

Your input will help guide our research.

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1 month ago

I'm hiring!

I am seeking a research assistant to support my fellowship research on arthritis pain. You'll join me in the fun, friendly and collaborative @wolfsonsparc.bsky.social

👉More details here: www.kcl.ac.uk/jobs/137085-...

⏰Closing date is 22nd February.
#painresearch #pain

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2 months ago

Cartoon transparent human with skeleton showing, red glowing points on joints to indicate pain

Do YOU live with joint pain?

Do YOU experience poor pain management?

Have you got 2-minutes to tell pain researchers about it?

If yes 👉 forms.gle/7NTwma2gnVN1...

We hope to gain insight into lived experience for those with joint pain & involve people in our #PainResearch 😃

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3 months ago

Looking forward to reading this!! Painless NGF seems to have moved away from p75 and onto TrkA biased signaling. www.biorxiv.org/content/10.1...

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5 months ago

Loss of peptidergic innervation of the subchondral bone in a murine model of MIA-induced osteoarthritis In the present study, we aimed to determine how osteoarthritis (OA) affects the morphology and distribution of nociceptive nerve endings in the subcho…

www.sciencedirect.com/science/arti...
Great paper from Jason Ivanusic’s lab: they imaged CGRP fibres in cleared joints and found a major loss of subchondral bone innervation in MIA vs controls—opposite to the idea of NGF-driven sprouting in OA. Does the MIA just wipe out the fibres?

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5 months ago

Please feel free to contact Stuart or me for further details

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5 months ago

The GIF shows GCaMP6s-labelled sensory neurons exhibiting spontaneous activity (visible as flickering) in a model of pain.

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5 months ago

Stuart Bevan and I are offering an exciting MRC DTP-funded PhD project exploring the mechanisms of pain in Long COVID.

Find out more about the project here:
🔗 tinyurl.com/3caseacv

Application deadline: 28th October

@wolfsonsparc.bsky.social y.social
@kingsioppn.bsky.social sioppn.bsky.social

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6 months ago

So good to see you former colleague 😆. Great talk as per usual. I hope to see you in Copenhagen soon!

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6 months ago

Great session, thanks for organising and nice to meet you.

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7 months ago

NKG2D receptor ligands are cell surface biomarkers for injured murine and human nociceptive sensory neurons Nociceptors are primary afferent neurons that sense noxious stimuli. They can be activated by tissue injury as well as the accompanying local immune response. We have shown that following nerve injury...

Neuronal subtype-specific expression of NKG2D ligands, injury models, and axonal degeneration? We have a new preprint @ndcnoxford.bsky.social
www.biorxiv.org/content/10.1...

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8 months ago

Claude Jay - Love Is The Answer (12" Club Mix 1986) YouTube video by Coolfunk Zézé 2

youtu.be/Y5AW3dtoIR4?...
And a tune to go with it!

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8 months ago

“Love is the answer”
#fluorescentfriday

8 µm longitudinal section of the Stellate Ganglion. Neurons expressing tdTomato (red). I love this one—these sympathetic neurons innervate the heart, and the section even resembles a heart emoji ❤️

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8 months ago

Hello Bluesky.
Thrilled to finally share some exciting news: I’ve been awarded a 5-year Career Development Fellowship from @versusarthritis.bsky.social to investigate the role of silent nociceptors in arthritis pain.
More info below in the PR.

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8 months ago

#PainResearch
Great PostDoc opportunity from Mat 🥳

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8 months ago

Psilocybin has no immediate or persistent analgesic effect in acute and chronic mouse pain models The psychedelic psilocybin may have lasting therapeutic effects for patients with chronic pain syndromes. Some clinical and preclinical data suggest these putative benefits derive from direct analgesic effects. However, this possibility has not been comprehensively tested in preclinical models. Here, we show that psilocybin is not analgesic over a range of doses across multiple pain assays and models of acute and chronic inflammatory, neuropathic, or musculoskeletal pain in mice. ### Competing Interest Statement B.D.H. is on the scientific advisory boards of Journey Clinical and Osmind, and is a paid consultant to Arcadia Medicine, Inc, Tactogen, LLC, and Vida Ventures, LLC. R.C.M. is now on leave from Stanford, functioning as Chief Scientific Officer at Bayshore Global Management. R.C.M. is on the scientific advisory boards of MapLight Therapeutics, Bright Minds, MindMed, and Aelis Farma. International Anesthesia Research Society, https://ror.org/0252rqe04, Mentored Research Award National Institute on Drug Abuse, T32DA035165, P50DA042012

www.biorxiv.org/content/10.1...

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8 months ago

Fabulous teamwork with @taamslab.bsky.social! Our findings provide a mechanistic explanation for why JAK inhibitors are better painkillers in #arthritis 🧪🧠 #PainResearch #PainScience #Immunosky

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