Daniel Blanco-Melo

GLUE Resources for Gene Families Comparative Genomics Across the Host–Pathogen Interface

Studying immune gene evolution is rarely about a lack of data, it’s about keeping data, biology, and interpretation aligned as everything changes.

New GLUE Genomics post: from viral genomes to immune genes, using interferon lambda as a case study.

gluetools.substack.com/p/glue-resou...

Standing ovation to @eeb222.bsky.social for powering through the many intricacies of this project. And huge thanks to @paleogenomics.bsky.social @jonploug.bsky.social JT McCrone, Mike Rutherford, Kathryn Kistler, Ale Castillo, Isabelle Du Plessis, @lauracarrillo.bsky.social & Ting Liu #ThankYouTeam💪🏼

Excited to share our work on #AncientRNA from alcohol-preserved lungs, recovering the oldest human RNA virus genome (an 18th-century rhinovirus). Our study shows that viral RNA remnants persist in centuries-old tissue, opening new ways to study virus evolution and historical disease #Paleovirology🫁🦠

Now live! Nearly all human genes contain multiple transcript isoforms - and the genes that predominantly control infection, ISGs, are no different. Using PacBio with analysis help from Yan Guo, Himadri noticed a never-before-seen transcript isoform of ISG15 that potently restricts flu 1/4

Happy to see @joelrc.bsky.social's paper identifying cellular heterogeneity in basal OASL expression as a major determinant of interferon induction during influenza virus infection out in its final form:

www.pnas.org/doi/10.1073/...

Happy new year, hope everyone's 2026 is better than 2025!

SMBE2026 Symposium 13 | Perspectives on paleo-omics: defining functional evolution of ancient viruses in the era of big data

SMBE2026 Symposium 13 | Perspectives on paleo-omics: defining functional evolution of ancient viruses in the era of big data

📨 Abstract submission
smbe2026.org/abstracts

📋 Programme details
smbe2026.org/programme

#SMBE2026

Ancient DNA insights into diverse pathogens and their hosts Nature Reviews Genetics - Ancient DNA techniques are being applied to study increasingly diverse pathogens of the past. The authors review the latest insights into pathogen–host coevolution,...

Lovely to work with @blevinske.bsky.social, @paleogenomics.bsky.social & Verena Schuenemann on " Ancient DNA insights into diverse pathogens and their hosts"! Read it at rdcu.be/eSVPN

🤬@&$!€£¥*

Actively looking for a postdoc interested in host-virus evolution. Please apply to the #MahanFellowship This fellowship provides early career scientists with the opportunity to join a Fred Hutch CompBio lab (like ours!). If interested please contact me to coordinate proposal and apply by Dec 05 2025

We mourn the passing of Nobel laureate David Baltimore, a towering figure in molecular biology and virology, and a pioneer and founder of ASV. His discoveries transformed science and medicine, and his mentorship inspired generations. His legacy will continue to guide and inspire virology and ASV.

25 Anniversary - HelpEndHIV https://vimeo.com/1080978050

HVTN 25th Anniversary:
The journey to an HIV vaccine 💪🏼

Full movie of this incredible 25yr effort 👇🏼

www.helpendhiv.org/25-anniversa...

On today's front page @nytimes.com

It was a pleasure to attend the first #APG2025 symposium at UNAM Juriquilla and to listen to great keynote lectures given by @christinawarinner.bsky.social and
@scs22.bsky.social. A big thanks to @dbm003.bsky.social and @paleogenomics.bsky.social and their organizing committee 👏.

📢📢One more day to submit your abstract to the Ancient Pathogen Genomics Symposium 🧬🦠🦴📢📢

Great program and community 💚

🔗 Details: liigh.unam.mx/apg/

🇲🇽 ¡Nos vemos en Querétaro! 🌮🪅

Our Diversity is our strength! #StandUpFor Science-Seattle

Seattle #StandUpForScience

Map of Stand Up for Science events, with official SUFS events in Red and solidarity events in Blue

WHERE WILL YOU BE ON MARCH 7TH!?

Head to www.standupforscience2025.org/local-event-information/ or the link in our bio to find your closest event—or add one if you're hosting one!

#standupforscience2025

Hello Again #Bluesky Im officially over with the #DeadBlueBird. Ready to engage with all of you and all things Viral #LoveVirology🦠

Program for the Ancient Pathogen Genomics symposium between April 12-13 2025.

🌍 Hello #AncientPathogens community! 🦴🧬🦠

APG's Preliminary Program is up!
Registration waivers for LMIC trainees (thanks to Novogene & Twist Bioscience)! 🙌Abstract deadline extended! ⏳

🔗 Details: liigh.unam.mx/apg/

🇲🇽 ¡Nos vemos en Querétaro! 🌮🪅

Please RT!

Thank you Alistair!

Very Happy to share the very first paper of the Lab! Qing Yang & Ben Nilsson-Payant found that modulating Influenza NS1 levels reveals a ranking in its inhibitory roles: IFN < ISGs < UPR. Huge thanks to Ben tenOever for his helpful advice! For many more to come 🥂
bit.ly/NS1Priority

Exciting work from @nandangokhale.bsky.social Nandan plans to continue studying how RNAs scaffold immune signaling platforms as an independent investigator, and is on the job market. Hire him!

www.biorxiv.org/content/10.1...

Hello #BlueSky friends! I work on #cancer #genomics in 🇲🇽, focused on acral #melanoma, #liver diseases and also on capacity building and training. We seek to generate genome sequences from cancer and pre-cancer from Latin America to study risk factors & contributors. Excited to join this community!

👩‍🔬New **PostDoc** Opportunity!👨‍🔬

My new Epidemiology & Virus Evolution (EVE) group at SwissTPH is looking for a PostDoc in evolution & phylogenetics of respiratory viruses 🦠🌳

Interested? See here for more details & to apply!
jobs.swisstph.ch/Vacancies/92...

Please share!😁

m7GpppNm - VERY EXCITED to share my postdoctoral work in @ramlabuw.bsky.social’s lab, now @bioRxiv. We find that cellular RNA interacts with MAVS, the adaptor protein of the RIG-I-like receptor pathway, to promote antiviral signaling. A 🧵:

We have an open virology faculty search at the University of Illinois! We have world class core facilities and a fantastic collaborative group of young faculty working on cutting edge questions in virus biology...you could be next!

Please re-post/RT/re-bleet/whatever it is called here!

Hello #AcademicBlueSky! Great to see you again. Ready to share and learn all things #LoveVirology