Trevor A. Crowell, MD, PhD

🥳 Awesome 2 catch up w/ #HopkinsFam @tcrowellmd.bsky.social & #AmitaGupta at #BigBash @#IDWEEK2025!!

Uganda's Anti-Homosexuality Act has devastated fight against HIV A study recently conducted by human rights activists and institutions from Uganda and the United States has revealed that the Anti-Homosexuality Bill (AHA)

"New study reveals huge drop in #Uganda’s queer people accessing #HIV prevention and care"

via @76crimes.bsky.social #IAS2025

Factors Associated With Interest in HIV Pre-exposure... : Journal of the Association of Nurses in AIDS Care 389 participants answered questions about PrEP interest. Of these, 53.7% were female, 72.2% were single, 55.5% completed secondary education, and 37.5% reported previous sex work. Their median age was...

PrEP interest and usage was suboptimal in a cohort of people with behavioral risk for #HIV in Western Kenya. Key correlates of PrEP interest included transactional sex, overnight travel, knowing someone taking PrEP, and belief in PrEP's efficacy.

journals.lww.com/janac/fullte...

Thrilled to be discussing the safety of analytic treatment interruption across several HIV cure studies in Thailand

@mhrp.bsky.social #ias2025 #HIV

Check out the full supplement from @jiasociety, “PEP in Africa: prospects, opportunities and challenges”. bit.ly/JIASPEP

#IDsky #episky #HIV #IAS2025

<em>Journal of the International AIDS Society</em> | IAS HIV Research Journal | Wiley Online Library Introduction HIV post-exposure prophylaxis (PEP) can prevent HIV acquisition and facilitates linkage to pre-exposure prophylaxis (PrEP) for people with ongoing vulnerability. We assessed PEP awarene.....

Excited to share lessons from the #MOCHIstudy about post‐exposure prophylaxis ( #PEP ) use in Kenya. PEP can prevent #HIV acquisition soon after exposure and can be a link to pre-exposure prophylaxis ( #PrEP ) for people with ongoing exposures. onlinelibrary.wiley.com/doi/10.1002/...

#IDsky #Episky

The countdown is on! #IAS2025 pre-conferences kick off in exactly 3 weeks!

📰 View the full conference programme: zurl.co/Nz3Fz

👥 Discover featured speakers: zurl.co/vVsez

☑️ Register to join us: zurl.co/HtskV

🌍 Discover what’s in store for #IAS2025, taking place in #Kigali and virtually, from 13 to 17 July!

🔎 Browse over 100 sessions, including plenary presentations, invited-speaker symposia, oral abstract sessions, pre-conferences and satellites:

zurl.co/x1g26

So important that the general public here’s this message and understands the danger in which our nation’s health has been placed.

Meet, Fredrick Sawe, MBCHB, MMED. Dr. Sawe is a 2023 award recipient of the ACTG James Hakim International Investigators Mentorship Award, recognizing his work in advancing the care of people living with HIV/AIDS and his service to the ACTG network.

actgnetwork.org/newsletter/

YouTube video by IAS-USA 40+ Years of HIV: What’s Changed, What Hasn’t, What Shouldn’t, What Must

A must-watch: Rebecca Denison, founder of Women Organized to Respond to Life-threatening Diseases (WORLD), delivers the Martin Delaney Presentation at #CROI2025

"40+ Years of #HIV: What’s Changed, What Hasn’t, What Shouldn’t, What Must"

Thanks to IAS-USA for making it publicly available.

ACTG Launches Second HIV Cure Clinical Trial in Africa ACTG Launches 2nd HIV Cure Clinical Trial in Africa Study Evaluating 2 Long-Acting Broadly Neutralizing Antibodies Given at HIV Treatment Initiation...

So excited and proud to be part of this work as ACTG launches its second HIV cure clinical trial in Africa!

www.globenewswire.com/news-release...

#HIV #IDSky #MedSky #GlobalHealth #PublicHealth

Prophylaxis Against Pneumocystis jirovecii Pneumonia in Adults This JAMA Insights Clinical Update discusses current recommendations regarding prevention of Pneumocystis pneumonia in patients who are immunocompromised.

ID rule of thumb is to prophylax against PJP when high-dose steroids are used (i.e. 20mg or more of prednisone daily) for 4 or more weeks. Prophylactic regimens and other indications for prophylaxis are reviewed nicely in the linked JAMA article.

www.doi.org/10.1001/jama...

Something was just different about Omicron. While many participants still experienced symptoms after their acute COVID-19, recovery was faster than with earlier variants. Disappointingly, prior vaccination did not impact recovery time.

rdcu.be/d6bS8

#MedSky #IDSky #PublicHealth #EpiSky

Discussion of HIV and Other Sexually Transmitted Infections ... : JAIDS Journal of Acquired Immune Deficiency Syndromes g a historically marginalized and presently criminalized community of sexual and gender minorities (SGM) in Nigeria. Methods: From 2013 to 2018, we enrolled SGM aged 18+ years in Lagos or 16+ years...

Talking openly about HIV and other STIs with sexual partners is one of the first steps toward safer sex. Data from this study with Nigerian colleagues show increased condom use when such discussions are had.

#IDSky #MedSky #EpiSky @mhrp.bsky.social

journals.lww.com/jaids/fullte...

Want to start a fight among virus experts? Ask about HIV’s new name HIV is now "Lentivirus humimdef1" by another name. Virus researchers are not happy.

"Lentivirus humimdef1"? Am I really going to have to start writing this in papers??

#IDSky #MedSky #HIV

www.statnews.com/2025/01/09/v... via @statnews.com

Evaluating the psychosocial experiences of participants in HIV cure research before, during, and after analytical treatment interruptions: A longitudinal qualitative study in the United States The lack of socio-behavioral research on stress and psychosocial experiences among research participants who undergo analytical treatment interruption…

Evaluating the psychosocial experiences of participants in #HIV cure research before, during, and after analytical treatment interruptions: A longitudinal qualitative study in the United States www.sciencedirect.com/science/arti... (subscription req for full text)

Mpox vaccination hesitancy, previous immunisation coverage, and vaccination readiness in the African region: a multinational survey Our findings indicate a significant level of hesitancy toward mpox vaccination in the African region. Individuals who have not previously received other vaccines are at a higher risk of refusing to vaccinate against mpox for themselves and for children. However, high vaccination readiness can help mitigate this risk. The study recommends that regions in Africa with low immunisation coverage should continue to enhance vaccination education and improve vaccination readiness to reduce hesitancy and promote the mpox vaccination program.

Data from this multinational study in Africa show substantial hesitancy to receive an mpox vaccine. To facilitate public health response to future outbreaks, we need to engage people proactively to build trust/confidence.

www.thelancet.com/journals/ecl...

#IDSky #EpiSky #globalhealth

Wastewater COVID-19 National and Regional Trends CDC’s National Wastewater Surveillance System, U.S. National trends

Wastewater data suggest an uptrend in COVID-19. Flu season is also upon us.

www.cdc.gov/nwss/rv/COVI...

#IDSky #MedSky #EpiSky

Jimmy Carter made eradicating Guinea worm disease a top mission Nobel Peace Prize winner Jimmy Carter spent decades waging war against an ancient parasite. Carter tried to rid the world of Guinea worm, which infects people who drink unclean water tainted with larv...

Jimmy Carter spent almost forty years after his presidency working to eliminate Guinea worm.

apnews.com/article/jimm...

#IDSky #EpiSky #MedSky

Norovirus cases are surging in parts of the US, CDC data shows The latest government data shows that cases of a fast-spreading stomach bug are surging in parts of the United States.

There has been an uptick in norovirus cases. Be vigilant with handwashing! 👏

apnews.com/article/noro...

#IDSky #MedSky

Rwanda and WHO declare end of Marburg outbreak after no new cases reported The World Health Organization and the Rwandan government have declared the outbreak in Rwanda of the Ebola-like Marburg fever over after no new cases were registered in recent weeks.

Fantastic public health response from Rwanda and Africa CDC contributed to the swift end to this Marburg outbreak.

apnews.com/article/rwan...

#IDSky #EpiSky #globalhealth #publichealth

Systems Vaccinology: Navigating the Future of Personalized Immunity and Next-Generation Vaccines Systems vaccinology integrates a range of “omics” technologies to identify key immune signatures and enhance vaccine development. This approach aids in understanding variations in immune responses, driven by genetics, health status, and the microbiome. Consequently, systems vaccinology helps pave the way for personalized vaccination strategies, essential for addressing diverse populations.

Systems Vaccinology: Navigating the Future of Personalized Immunity and Next-Generation Vaccines

#IDSky

Nigeria activates emergency response as Lassa fever kills 190 this year Nigeria has launched an emergency response centre after recording 190 deaths from Lassa fever, a viral hemorrhagic illness, the country's disease control agency said on Monday.

Nigeria has launched an emergency response centre after recording 190 deaths from Lassa fever, a viral hemorrhagic illness transmitted to humans via rodent and other animal hosts.

www.reuters.com/world/africa...

#IDSky #EpiSky #MedSky #GlobalHealth #PublicHealth

Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. The drug attaches to the lattice-like capsid proteins that shield the virus’s genetic material—a mechanism that could inspire other antivirals. Lenacapavir could help end the HIV/AIDS epidemic, but that will hinge on access for those who need it most.

Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months.

Learn more about this year's #BOTY and other big advances in science: scim.ag/3BrCtUn

Susceptible!

Does the world still need an HIV vaccine? Experts say yes Fifteen years ago, an HIV vaccine trial conducted in Thailand and sponsored by the U.S. Army found something no other HIV vaccine trial ever had: a regimen that seemed to work.

Long-acting injectables are poised to change the landscape of HIV prevention, allowing people to go months in between doses of PrEP. In the era of lenacapavir and cabotegravir, does the world still need an HIV vaccine? I asked around and got one answer. #HIVSky #IDSky

www.healio.com/news/infecti...

Scholarships | IAS 2025 If you are at least 18 years old on 13 July 2025 and working, volunteering or studying in the area of HIV, you are welcome to apply for a scholarship for IAS 2025. Apply now

🌟 #IAS2025 scholarship applications are now open!

If you are at least 18 years old on 13 July 2025 & working, volunteering or studying in the area of #HIV, you can apply for a scholarship to join us in #Kigali, #Rwanda, from 13-17 July 2025!

☑️ Apply by 22 January: www.iasociety.org/conferences/...

Ten Americas: a systematic analysis of life expectancy disparities in the USA - @thelancet.bsky.social

Somber update on the 8 Americas study; highlights growing inequities in life expectancy, impact of structural racism and disproportionate impact of #COVID19

www.thelancet.com/journals/lan...

go.bsky.app/B9SSKaq