@thomaslecuit.bsky.social
How are biological forms encoded? Group leader at IBDM Marseille, director of Turing Center for living systems (CENTURI). Professor at Collège de France, Paris: Dynamics of living systems
Wonderful to be part of exciting Program at Harvard University & CMSA, Mathematics &Biology: Morphometry, Morphogenesis and Mathematics. Thank you 🙏🏼 and congrats to organizers for their invitation. Great to see and discuss with wonderful colleagues, not least @akankshi.bsky.social! 🤩
03.03.2026 11:00 — 👍 16 🔁 2 💬 0 📌 0
Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate www.nature.com/articles/s41... #jcampubs
25.02.2026 17:06 — 👍 51 🔁 23 💬 0 📌 2
New paper out! In this project, we focused on the question how tissue mechanics is spatially controlled during development. We show that the GPCR ligand Fog acts as a “mechanogen” during Drosophila gastrulation, driving a self-organized wave of tissue invagination:
www.nature.com/articles/s41...
Spring is just around the corner in Marseille 😊
19.02.2026 10:44 — 👍 16 🔁 0 💬 2 📌 0
Very sad news. Gail Martin (1944-2026) was a figure in developmental biology. She pioneered the field of ES cells.
A great colleague, a friend and a lovely person.
Huge congrats to @manuelthery.bsky.social and all the Cytomorpho lab. The "Living Architectures" performance at @museeorsay.bsky.social was breathtakingly beautiful
25.01.2026 09:22 — 👍 145 🔁 37 💬 5 📌 2
A few seconds of eternity: From microscope to museum❣️
It was truly delightful to be part of this project, celebrating life as a continuous dance of creation, collapse, and renewal. 🔄
Kudos to @manuelthery.bsky.social @lblanchoin.bsky.social #cytomorpholab members, and @museeorsay.bsky.social
This weekend we projected cells and filaments on the roof of the @museeorsay.bsky.social in Paris, then we contracted it with a pinch of myosin.
And it was fabulous!
Grateful to have been part of this art/science project & thx to @manuelthery.bsky.social @lblanchoin.bsky.social & the CytoMorphoLab
Very nice dinner with colleagues from Institut Pasteur, Francois Schweisguth, Romain @levayerr.bsky.social , Thomas Gregor and @jeromegros.bsky.social 🤩. I look forward to more discussions and to giving my seminar tomorrow ! Thank you for the great invitation.
12.02.2026 22:30 — 👍 14 🔁 0 💬 0 📌 0
I made a map of 3.4 million Bluesky users - see if you can find yourself!
bluesky-map.theo.io
I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
Last but not least, @NCBS_Bangalore hosts remarkable plants and biodiversity. The garden is beautiful, at any season. Always refreshing to be exposed to nature while working on « life in a lab »… a glimpse below 🤩
07.02.2026 11:16 — 👍 7 🔁 0 💬 0 📌 0
Another treat visiting ICTS, welcomed & stimulated by @vijaykrishnamurthy.bsky.social Exciting work on non-trivial & remarkable interactions btw mechanics & geometry in morphogenesis.
Check what will come out…
+ Do visit ICTS biological physics groups. 🙏🏼 for hosting me!
A very interesting article « De novo emergence of metabolically active protocols ». Complex chemistry, organisation from few input constituants. Very intriguing.
Congrats Shashi Thutupalli and colleagues @stpalli
Link:
arxiv.org/abs/2601.11013
Among outstanding scientists @ncbsbangalore.bsky.social are the physicists. Colleagues & friends Madan Rao, Mukund Thattai, @stpalli Shashi Thutupalli, w. visitors Shiva GV, Irene Giardina. Always learn from them. Great discussions on Information & computation in biology.
07.02.2026 11:06 — 👍 4 🔁 0 💬 0 📌 0
15 yrs ago, I spent 1y sabbatical @ncbsbangalore.bsky.social , with family, hosted by @kvijayraghavan.bsky.social , starting long standing coll. with Jitu Mayor & Madan Rao. The discovery of this exceptionally diverse, creative & energetic community transformed me 🤩. Huge 🙏🏼
07.02.2026 11:05 — 👍 9 🔁 1 💬 0 📌 0
Happy to highlight our collaborative work from our @ijmonod.bsky.social team with @destriano.bsky.social, B. Goyeau and M. Chabanon.
Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity.
Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
very sad news. Peer Bork was one of the leaders of our field, a wonderful scientist, and he's much too young to be gone. www.embl.org/news/embl-an...
16.01.2026 18:33 — 👍 144 🔁 82 💬 10 📌 7
Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de
A screenshot of the 'The hard truth about how hard it is to publish in Development' article PDF.
The hard truth about how hard it is to publish in Development
Editor-in-Chief @jamesbriscoe.bsky.social leads our team of Academic Editors in addressing the perception that Development is ‘too hard to publish in’ by discussing the journal's review process.
doi.org/10.1242/dev....
Is there a mathematics of discontinuous behavior? Christopher Zeeman was a leading proponent of Catastrophe Theory, a topological approach to sudden change that underpins much of today’s work on tipping points. This is his beautiful 1976 paper in @sciam.bsky.social www.jstor.org/stable/pdf/2...
12.01.2026 23:27 — 👍 58 🔁 14 💬 2 📌 1
Wonderful dinner in Paris with Claude Desplan, 1st mentor (who led me to become a scientist because his lab was such a cool place) & friend. Thank you for your energy, shear passion for science and sense of humour 🤩. And see you soon at the College de France in May June for your lecture series.
08.01.2026 16:19 — 👍 10 🔁 0 💬 0 📌 0
How can cells use information from neighboring cells to improve the spatial precision of morphogen patterns? 🤔
We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns.
buff.ly/w56OUJT
Super nice to see this awesome set of lectures online! A really timely perspective on biology through the lens of information, which inspires much of our own research as well.
05.01.2026 08:34 — 👍 10 🔁 2 💬 0 📌 0
The CENTURI PhD Call 2026 is still ongoing. Applications are open until the end of the month, on January 28th!
Visit centuri-livingsystems.org/recruitment/ to apply.
#PHD #CENTURI
Here is the link to download the PDF of my course#5 on Biological computation. I present & discuss Self-tuning, Adaptation and Learning in biological (non-neuronal) systems, in particular during embryonic development.
This course contains various personal ideas/proposals.
tinyurl.com/hcpwsbtm
Please find below the link to watch the VIDEO of my course#5 @college-de-france.fr on Biological computation. I present and discuss Self-tuning, Adaptation and Learning in biological (non/neuronal) systems, in particular during embryonic development.
Enjoy!
tinyurl.com/4pv95an9
#Science #Biologie
🧬 « Qu’est-ce que l’information biologique (suite) ? »
🖥️ Le cours du Pr @thomaslecuit.bsky.social, titulaire de la chaire Dynamiques du vivant, est terminé... mais toutes les vidéos sont à retrouver sur notre site web !
👉 https://tinyurl.com/bddcxahd
And here is the PDF of the 4th course @college-de-france.fr. You will find the justification and presentation of geometric representation of cell decisions, a parsimonious mathematical model for signalling and cell state transitions
tinyurl.com/yc7u296j
Please find below the link to watch the VIDEO of my course#4 @college-de-france.fr on Biological computation. I present and discuss Geometric analysis of cell decisions during development, a mathematical formulation of Waddington landscapes.
Enjoy!
tinyurl.com/3zay96xx
Have you ever wondered what you would find if you could keep your eyes on a bee for more than a few meters? Us, too!
preprint (with videos!) + thread 🧵
Precise, individualized foraging flights in honey #bees 🐝 revealed by multicopter drone-based tracking
www.biorxiv.org/content/10.6...
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