Mel Sharpe

My first GRC amygdala in Barcelona hosted by @katewassum.bsky.social did not disappoint! Can’t wait for the next one with @joserodroma.bsky.social and @annabeyerle.bsky.social! ☀️🕶️🌴🌊

Cancers can be detected in bloodstream three years prior to diagnosis Detection of cancer before a clinical diagnosis could give patients and caregivers more time for intervention and may lead to better outcomes because tumors are more likely to be curable

Genetic material shed by tumors can be detected in the bloodstream three years before cancer diagnosis, according to a study led by investigators at Johns Hopkins University.

That study was made possible with federal funding. Now, many studies like this are canceled. hub.jhu.edu/2025/06/04/...

Prefrontal encoding of an internal model for emotional inference - Nature Neurons in the rodent dorsomedial prefrontal cortex encode a flexible internal model of emotion by linking directly experienced and inferred associations with aversive experiences.

... neurons in the rodent dorsomedial prefrontal cortex (dmPFC) [link] sensory stimuli in the environment with aversive events, whether they were directly or *indirectly* associated with that experience....

by the amazing lab of @jojolab.bsky.social

🧠📈

www.nature.com/articles/s41...

Dopaminergic processes predict temporal distortions in event memory Our memories do not simply keep time - they warp it, bending the past to fit the structure of our experiences. For example, people tend to remember items as occurring farther apart in time if they spa...

New from our lab: your brain doesn’t just remember time - it bends it.

We show that the dopamine system responds to natural breakpoints in experience, and this relates to more stretched memories of time. Blinking also increases, signaling encoding of new memories.

www.biorxiv.org/content/10.1...

I have Tycho on repeat 🌈

#whatkeepsmeinscience #community

Yes! We need to see more of this. 🧪

One of the most epic trips of my life! Joshua Tree retreat with 11 of the most inspirational neuroscientists I know!

Thx to Moriel Z and Bianca JM for organizing. And featuring Michelin star chef and yoga instructor @denisejcai.bsky.social

Forever grateful for this crew

Until next year ❤️

🧪🧠

Who’s coming to Sydney!?

It's gonna be epic!

All info and relevant forms, here: pavlovian.org/upcoming-mee...

🚨LAST DAY to submit poster abstracts for the PAVLOVIAN 2025 annual meeting 🚨

Check out our 🔥 program and submit abstracts in the link below, with 5 travel awards available for students and postdocs! 🧠

Chen Institute Workshop on Cross-Species Modalities in Cognition and Behavior

Anyone up for some cross-species discussions at Caltech on Friday afternoon? neuroscience.caltech.edu/programs/wor...

An inscopix miniaturized microscope! The lens is implanted in the brain, and the microscope images through the lens.

Big news from the lab this week! Successfully recorded lateral hypothalamic GABA neurons in freely moving rats using single-unit calcium imaging ! Led by a phenomenal postdoc in the lab, Jess Leake.

And just in time for that grant deadline 🔥 🧠

Kill me.

… and of course I’m on a grant deadline 😭

I will salute you if you manage to find a good time to use that one 🫡

Nice- looking forward to reading it!

WTF?! 👇 Asprin reduces cancer metastasis?! @nature.com

Nothing better than a well-time touché 😝

Thanks, Tony! It’s great to be back 😃

Been pinning up my favorite papers from the lab 🧪 that we’ve published since we got to Sydney 🇦🇺 ☀️

Going to have to take down the pics of my kid soon 😉 🧠

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

AOC and Bernie in front of the rally crowd in Denver

Zoomed out crowd shot of 34,000 people in downtown Denver with Colorado mountains in the background

Tonight an unbelievable **34,000 people** gathered for our Denver rally to take on billionaires and win our country back.

This was the largest political gathering in Denver since Obama in 2008.

Also bigger than the 2024 DNC.

And the largest ever rally in Bernie’s career (and obviously, mine too).

Congrats, Bridge! Well deserved.

Technically effective July 1st, but I need a celebration today. You are looking at Associate Professor with Tenure at UCLA. Tickled pink! 🤓🥳

Don’t forget to submit your data blitz or poster abstracts for PAVLOVIAN in SYDNEY!🧪🧠

Due April 11th, including 5 x travel awards to help our buddies from the 🇺🇸 and elsewhere get to 🇦🇺

Our line up is 🔥 Check out our website, registration, and hotel block below 👇

Great news. Long term
Independence for biorxiv and medrxiv.

As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine HPV can cause a variety of cancers, including cervical. New mortality data for women under 25 point to the success of the HPV vaccine.

There is a vaccine against a virus that causes a particularly pernicious cancer, and since it was introduced deaths from that cancer have dropped by more than 60%. An unmitigated triumph of human genius.

www.sciencefriday.com/segments/hpv...