Dr David Joffe MB BS(Hons), PhD, FRACP

Unveiling the Intricacies of Implicit Motor Learning in Adults Recovered from COVID-19 COVID-19 is primarily a respiratory illness, but it has been linked to persistent neurocognitive deficits. Given the prefrontal cortex’s role in cognitive-motor processing and implicit motor learni...

🧠 Daily Feed of Brain Damage 🧠

www.tandfonline.com/doi/full/10....

There are many pathways to destruction... APS is autoimmune with a side serve of thrombosis.

Direct gliosis pre-frontal cortex and amygdala. Hypoperfusion. Glymphatic drainage obstruction.

It's a collective attack on the organ of everything. The one you cannot transplant

Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement AbstractStudy Objectives. Our study introduced the 2023 UK Biobank sleep questionnaire and described variation in sleep health dimensions and prevalence of

Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement url: academic.oup.com/sleep/articl...

www.hhs.gov/longcovid/in...

Thanks, Mark

My slide collection thanks you too😊

Receptor-mediated mechanisms underlying neurological complications in COVID-19: from viral entry to neuroinflammation - 3 Biotech Neurological complications of COVID-19 encompass acute syndromes and persistent post-acute sequelae, yet their mechanistic basis remains incompletely defined. Integrated clinical, neuropathological, n...

🧠 Daily Feed of Brain Damage 🧠

@atranscendedman.bsky.social 🙏🏻

link.springer.com/article/10.1...

Touché

I was waiting for you to knock on the door, My Friend 😂😂😂

Hmmmm....

I wonder if the:

🧠 Daily Feed of Brain Damage 🧠
Applies here:

CMAJ 2026 March 9;198:E313-25. doi: 10.1503/cmaj.251065

🧠 Daily Feed of Brain Damage 🧠

@atranscendedman.bsky.social 🙏🏻

doi.org/10.1093/brai...

👍🏻👍🏻

🧠 Daily Feed of Brain Damage 🧠

@atranscendedman.bsky.social 🙏🏻

www.nature.com/articles/s41...

Could Positive Airway Pressure (PAP) Enhance Brain Waste Clearance and Modify Neurodegenerative Risk? A Perspective on Sleep-Dependent CSF–Lymphatic Pathways Abstract. Obstructive sleep apnea (OSA) is linked to cognitive decline and is increasingly implicated in neurodegenerative trajectories. Continuous positiv

Reasons those with Long Covid should have a PSG.

Could Positive Airway Pressure (PAP) Enhance Brain Waste Clearance and Modify Neurodegenerative Risk? A Perspective on Sleep-Dependent CSF–Lymphatic Pathways url: academic.oup.com/sleep/articl...

Frontiers | Dysregulated NK-cell gene expression defines the enduring symptoms of long COVID-19 IntroductionLong-term COVID-19 syndrome (LTCS) or “long COVID” is a debilitating post-viral condition affecting approximately 2%–8% of individuals after SARS...

The #Leonardi_Effect are strong.

Up your nose and away it goes.

It would seem the depletion of NK Cells contributes to Long Cövid 🙏🏻

www.frontiersin.org/journals/imm...

🤬🤬

😂😂

AI - The new version of "Replacement Theory"....

I'm not overly excited nor optimistic... I'm a happy Neanderthal 🙈

It may be available online. I've zero experience

They can be positive within 12 hours to be honest. It's all about viral load 🙏🏻

Prevalence and Symptoms of Post-COVID-19 Syndrome in Active-Duty Military Personnel Post-acute COVID-19 is a syndrome characterized by the persistence of clinical symptoms beyond 4 weeks from the onset of acute symptoms. Over 250,000 Department of Defense service members have recover...

Perhaps this explains the US's lacklustre performance at the military level....

The Hesgeth Factor is likely a huge confounder 🤬🤬

www.amjmedsci.org/article/S000...

That's varied considerably between strains. I would suggest that the asymptomatic infections are likewise strain dependent 🙏🏻

Thank You, Jonathan....

It's was a lot of fun to chat 😊😊🙏🏻

From the other place....

Priceless 😂😂

The impact of testing positive versus negative for COVID-19 on health-related quality of life: cross-sectional evidence from the Alberta post-COVID-19 follow-up survey - Quality of Life Research Quality of Life Research - The novel Coronavirus Disease 2019 (COVID-19) can have lasting physical and psychological outcomes, though little is known about the long-term impact of COVID-19 on the...

I'll just leave this here:

👇🏻👇🏻👇🏻👇🏻

doi.org/10.1007/s111...

Risk of influenza and COVID-19 illness and pediatric obstructive sleep apnea: a TriNetX cohort with 5-year follow-up - Journal of Clinical Sleep Medicine Background Obstructive sleep apnea (OSA) is associated with impaired immune responses. Prior small-scale investigations suggested that pediatric OSA leads to a more severe clinical course of common ch...

link.springer.com/article/10.1...

I'm sorry for your loss

💔💔😔

Objective assessment of long-term impact of COVID-19 on multiple sensory functions - BMC Medicine Background This ongoing study investigates the impact of post-acute sequelae of SARS-CoV-2 infection (PASC) on broad sensory functions. Methods Sixty subjects aged 27–78 years were recruited who had c...

🧠 Daily Feed of Brain Damage 🧠

doi.org/10.1186/s129...

The fatigue spectrum in a community-based long haul COVID cohort - Sleep and Breathing Introduction In a Long Haul COVID referral clinic we describe the primary presentations of fatigue according to the CDC 2015 criteria for myalgic encephalitis/chronic fatigue syndrome (ME/CFS). Method...

MECFS versus Long Cövid in the Sleep literature

link.springer.com/article/10.1...

A Preliminary Investigation of Dopamine Transporter Binding Abnormalities in Individuals With Autism Spectrum Disorder In the emerging literature on aging and autism, a consistently replicated finding is a significantly increased risk for Parkinson's disease (PD), up to six times higher. Also, atypical dopamine activ...

Reminder:

Cövid is Dopa senescent

doi.org/10.1002/aur....

Long‐COVID‐19 Symptoms are associated with Abnormal Cognitive Testing and Mild Cognitive Impairment Compared to Controls Background There is a paucity of data comparing neuropsychiatric testing in patients with post-acute COVID-19 symptoms (“long-COVID”) to COVID-19 patients without long-term symptoms and to COVID-19 ...

🧠 Daily Feed of Brain Damage 🧠

doi.org/10.1002/alz7...

Kidneys and Cövid
@thecovidinfoguy.bsky.social 🙏🏻

www.nature.com/articles/s43...