Karl Koehler

The latest story from my group. Working toward build regionally distinct skin and amnion piece by piece.

📢 The September Issue of the JID is here!
Explore the latest issue here:
www.jidonline.org/current

#DermatologyJournal #dermsky

On the cover: A cross-section of a 146 day-old hair-bearing skin organoid derived from human pluripotent stem cells.
@krkoehler.bsky.social @BostonChildrens.bsky.social

I'm moderating the upcoming ISSCR Digital Webinar. Join me! Register now

I am moderating the upcoming ISSCR Digital Webinar: Modeling Human Neural Development and Disease with iPSCs. Join me to explore the latest science on neural development, disease mechanisms, and genetic variability from ISSCR 2025 Poster Award Winners. invt.io/1bxbs3ez8ty

Organoids: modelling organ development and disease in 3D

Yes, check here for details: www.embl.org/about/info/c...

All #organoid enthusiasts, please consider joining us in Heidelberg, Germany, October 2025. My co-organizers, Meri Huch, @lancasterlab.bsky.social, Esther Schnapp, and I have assembled an excellent speaker list, with keynotes from Paola Arlotta and Matthias Lütolf. Hope to see you there!

A panoramic view of cell population dynamics in mammalian aging To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...

Excited to share our work @science.org. led by our incredible @tommyz626.bsky.social at @rockefelleruniv.bsky.social! By profiling 21 million single cells across life stages, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific time windows!

Happy to be included here, too. Thanks for curating!

Thanks, Rajini! Feel free to reach out if you take this approach. We have a new Fellow in our group interested in rare skin disorders.

Love it. We have been generating retinal organoids lately, too. Should think about making an assembloid. 🤔

Posting one of my favorite #organoid images for #microscopymonday. A 100+ day-old skin organoid with emerging hair follicles (ECAD, cyan) and endothelial cells (CD31, red). See: www.nature.com/immersive/d4.... Credit: Jiyoon Lee and Matt Steinhart from our lab. #devbio #stemcells

#Organoid research starter pack.
I didn't find many researchers from the field yet, please comment/text me to be added!
go.bsky.app/RmXgs6d

Happy to join, too!

Science Magazine on LinkedIn: This light-sheet microscopy three-dimensional rendering shows a… This light-sheet microscopy three-dimensional rendering shows a first-of-its-kind mouse whole-brain mRNA analysis at single-cell resolution. Learn more in…

Thrilled to announce that our latest work has been published in Science and featured on the front cover!

www.linkedin.com/posts/scienc...

A prenatal skin atlas reveals immune regulation of human skin morphogenesis Nature - A comprehensive multi-omics reference atlas of prenatal human skin shows that innate immune cells crosstalk with non-immune cells to perform pivotal roles in skin morphogenesis, including...

Exciting to see the collection of HCA papers out this week in Nature. Honored to be in the mix with our collaboration with @mhaniffa.bsky.social and Sarah Teichmann on a fetal skin atlas. Bravo to Hudaa, Elena, and Bayanne et al, for pulling this study together. A tremendous effort! rdcu.be/d02Yx

The Human Cell Atlas: towards a first draft atlas In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.

A collection published across Nature Portfolio journals presents early draft maps of cells in the human body from the Human Cell Atlas initiative. The research leverages new data and analytical tools to aid our understanding of human health and disease at a cellular level. 🧪

Thanks for curating this list! Please add me too.