Karl Koehler's Avatar

Karl Koehler

@krkoehler.bsky.social

Neurobiologist and #organoid wrangler Associate Professor, #otolaryngology, #neurobiology @Bostonchildrens.bsky.social @Harvardmed.bsky.social Studying sensory #development through inner ear, skin and retinal organoids Lab: https://koehler-lab.org

920 Followers  |  699 Following  |  10 Posts  |  Joined: 21.11.2024  |  2.0726

Latest posts by krkoehler.bsky.social on Bluesky

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πŸ“’ The September Issue of the JID is here!
Explore the latest issue here:
www.jidonline.org/current

#DermatologyJournal #dermsky

On the cover: A cross-section of a 146 day-old hair-bearing skin organoid derived from human pluripotent stem cells.
@krkoehler.bsky.social @BostonChildrens.bsky.social

23.08.2025 17:34 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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I'm moderating the upcoming ISSCR Digital Webinar. Join me! Register now

I am moderating the upcoming ISSCR Digital Webinar: Modeling Human Neural Development and Disease with iPSCs. Join me to explore the latest science on neural development, disease mechanisms, and genetic variability from ISSCR 2025 Poster Award Winners. invt.io/1bxbs3ez8ty

21.07.2025 16:25 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Organoids: modelling organ development and disease in 3D

Yes, check here for details: www.embl.org/about/info/c...

20.12.2024 17:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

All #organoid enthusiasts, please consider joining us in Heidelberg, Germany, October 2025. My co-organizers, Meri Huch, @lancasterlab.bsky.social, Esther Schnapp, and I have assembled an excellent speaker list, with keynotes from Paola Arlotta and Matthias LΓΌtolf. Hope to see you there!

20.12.2024 13:44 β€” πŸ‘ 16    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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A panoramic view of cell population dynamics in mammalian aging To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome atlas profiling over 20 million cells from 623 mouse tissues across different life stages, se...


Excited to share our work @science.org. led by our incredible @tommyz626.bsky.social at @rockefelleruniv.bsky.social! By profiling 21 million single cells across life stages, we reveal aging as distinct, development-like transitions, with dramatic cell population changes in specific time windows!

29.11.2024 16:17 β€” πŸ‘ 195    πŸ” 77    πŸ’¬ 12    πŸ“Œ 3

Happy to be included here, too. Thanks for curating!

27.11.2024 13:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thanks, Rajini! Feel free to reach out if you take this approach. We have a new Fellow in our group interested in rare skin disorders.

25.11.2024 17:24 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Love it. We have been generating retinal organoids lately, too. Should think about making an assembloid. πŸ€”

25.11.2024 17:22 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Posting one of my favorite #organoid images for #microscopymonday. A 100+ day-old skin organoid with emerging hair follicles (ECAD, cyan) and endothelial cells (CD31, red). See: www.nature.com/immersive/d4.... Credit: Jiyoon Lee and Matt Steinhart from our lab. #devbio #stemcells

25.11.2024 15:53 β€” πŸ‘ 185    πŸ” 24    πŸ’¬ 10    πŸ“Œ 3

#Organoid research starter pack.
I didn't find many researchers from the field yet, please comment/text me to be added!
go.bsky.app/RmXgs6d

24.11.2024 08:32 β€” πŸ‘ 92    πŸ” 52    πŸ’¬ 64    πŸ“Œ 4

Happy to join, too!

24.11.2024 19:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Science Magazine on LinkedIn: This light-sheet microscopy three-dimensional rendering shows a… This light-sheet microscopy three-dimensional rendering shows a first-of-its-kind mouse whole-brain mRNA analysis at single-cell resolution. Learn more in…

Thrilled to announce that our latest work has been published in Science and featured on the front cover!

www.linkedin.com/posts/scienc...

22.11.2024 00:43 β€” πŸ‘ 53    πŸ” 12    πŸ’¬ 4    πŸ“Œ 3
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A prenatal skin atlas reveals immune regulation of human skin morphogenesis Nature - A comprehensive multi-omics reference atlas of prenatal human skin shows that innate immune cells crosstalk with non-immune cells to perform pivotal roles in skin morphogenesis, including...

Exciting to see the collection of HCA papers out this week in Nature. Honored to be in the mix with our collaboration with @mhaniffa.bsky.social and Sarah Teichmann on a fetal skin atlas. Bravo to Hudaa, Elena, and Bayanne et al, for pulling this study together. A tremendous effort! rdcu.be/d02Yx

21.11.2024 18:34 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 2    πŸ“Œ 0
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The Human Cell Atlas: towards a first draft atlas In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.

A collection published across Nature Portfolio journals presents early draft maps of cells in the human body from the Human Cell Atlas initiative. The research leverages new data and analytical tools to aid our understanding of human health and disease at a cellular level. πŸ§ͺ

20.11.2024 16:46 β€” πŸ‘ 126    πŸ” 29    πŸ’¬ 0    πŸ“Œ 6

Thanks for curating this list! Please add me too.

21.11.2024 16:58 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

@krkoehler is following 20 prominent accounts