Theoretical Biophysics

Delighted to announce “Hydrodynamic Approaches to Active Matter: Successes and Future Challenges”, will now take place on 6–10 October 2025 at @mpipks.bsky.social, on the occasion of John Toner’s 71st birthday. We hope you will join us.

www.pks.mpg.de/haam26

Tomorrow at #NeurIPS2025! Oral at 10 am in UL Ballroom 20D and poster #2016 at 11 am. @haydari.bsky.social and I are looking forward to hearing your thoughts.

Neural Network Circuit for Operant Conditioning with Blocking and Overshadowing Effects Based on DNA Strand Displacement Operant conditioning reflects the ability of organisms to adapt and learn. By implementing operant conditioning neural networks, complex brain-like behaviors can be simulated and learned at the molecular level. In this paper, an operant conditioning circuit with blocking effect and overshadowing effect is proposed by DNA strand displacement technique. The network can achieve blocking and overshadowing effects in the presence of multiple inputs. First, we construct DNA memristors using DNA strand displacement technology. The constructed DNA memristors are plastic and nonvolatile, which is very similar to biological synapses. The synaptic circuits constructed by DNA memristors have short-term plasticity, long-term plasticity, potentiation plasticity and depression plasticity. Second, the learning module, forgetting module, synaptic module, decision module and feedback module are constructed, and the operant conditioning circuit is realized. In addition, the operant conditioning circuit has relearning effect. Blocking and masking effects can also be achieved in the presence of multiple inputs. Finally, the reliability of the circuit is verified by the simulation of Visual DSD software. Our work demonstrates the potential of DNA molecules to build complex intelligent systems and provides an idea for using DNA molecules to achieve artificial intelligence.

Neural Network Circuit for Operant Conditioning with Blocking and Overshadowing Effects Based on DNA Strand Displacement
pubs.acs.org/doi/10.1021/...

📜We are thrilled to announce that the latest MorphoNet paper is officially published 🎉 ! Discover 5 varied use cases in which MorphoNet helps segment, curate, evaluate & validate complex 3D+t datasets, and much more 🧑‍💻 ! Read at @elife.bsky.social : doi.org/10.7554/eLif...

P.s.: We are always looking for collaborators for the Theoretical Biophysics Channels!

Have you spotted a scientific conference in theoretical biophysics, computational life sciences, microbial ecology, or related fields?

Contribute to our community updating the conference list

sites.google.com/view/theoret...

Your input helps accessible science to all researchers!

Clarke, D. N., & Martin, A. C. (2021). Actin-based force generation and cell adhesion in tissue morphogenesis. Current Biology, 31(10), R667–R680. #EpithelialMechanicsReview
doi.org/10.1016/j.cu...

www.icbp2026.org

Hi Maxime :), not sure about the future since I am looking for new (more stable and higher) position therefore probably not going. Are you? :)

Konstanz school of Collective Behavior will take place again from 20th July to 7th August , 2026. We have an amazing line up of speakers covering state of the art research on collective behavior across systems. Application deadline : March 15th
Details here: www.exc.uni-konstanz.de/kscb/applica...

Diagram illustrating "feed the enemy's enemy": ampicillin inhibits Pseudomonas aeruginosa. Citrobacter freundii acidifies the environment, further inhibiting P. aeruginosa.

New preprint from our lab www.biorxiv.org/content/10.1...! Andrea Dos Santos and Clément Vulin combine experiments and models showing how adding glucose can strengthen negative interactions between microbial species. This can be used in tandem with antibiotic treatment to inhibit pathogens!

Hi, I’m David Brückner @davidbrueckner.bsky.social.

I’ll take you through how cells in a tissue can use information distributed by biochemical gradients to make decisions, and how we can measure such positional information.

buff.ly/RFxVeHh

Resource allocation models: theory and applications in microbial biotechnology
doi.org/10.1016/j.co...

A niche for ecology and evolution in microbial biotechnology Bioengineering offers potential advancements in health, manufacturing, and environmental remediation, but without involvement from ecologists and evolutionary biologists the impact of environmental bi...

A niche for ecology and evolution in microbial biotechnology

@cp-trendsecolevo.bsky.social SCIENCE & SOCIETY by Callie Chappell and @jonshurin.bsky.social

www.cell.com/trends/ecolo...

We're at 735 registrants and counting! 🎉🦠

If you haven't registered yet, don't miss out on this exciting (free) symposium on gut microbial metabolites and their impacts on host health.

Please share with your networks. 🔗👇

isbscience.org/events/2025-...

How do brain areas control each other? 🧠🎛️

✨In our NeurIPS 2025 Spotlight paper, we introduce a data-driven framework to answer this question using deep learning, nonlinear control, and differential geometry.🧵⬇️

1/6 New preprint 🚀 How does the cortex learn to represent things and how they move without reconstructing sensory stimuli? We developed a circuit-centric recurrent predictive learning (RPL) model based on JEPAs.
🔗 doi.org/10.1101/2025...
Led by @atenagm.bsky.social @mshalvagal.bsky.social

Physique des cellules et cancer UMR168

Wednesday, 03/12/2025 11:30 am

Centre de recherche - Paris Amphithéâtre Marie Curie

Aleksandra Radenovic  

Institute of Bioengineering, School of Engineering, Swiss Federal Institute of Technology Lausanne, Switzerland

«Advancing Single-Molecule Imaging »

cambridgeblog.org/2025/10/univ...

www.cambridge.org/gb/universit...

Universal Biology: The Physics of Life through the Macro-Micro Consistency Principle Universal Biology: The Physics of Life through the Macro-Micro Consistency Principle : Kaneko, Kunihiko: Amazon.de: Books

Our friend Kunihiko Kaneko published his new amazing book!

"Universal Biology: The Physics of Life through the Macro-Micro Consistency Principle"

An insights into biology from physics perspective providing picture of the universal characteristics of living systems across scales

We got published in Ecology&Evolution! We propose an equation from which we derive the fundamental equations of population ecology and evolutionary biology (the Price equation). #evobio #philbio onlinelibrary.wiley.com/doi/10.1002/...

Bacterial networks #BacNet26 in September 2026 will be chaired by @lalouxlab.bsky.social and co-chaired by @s-lab.bsky.social with @coralietesseur.bsky.social

Sneak peak on invited speakers and preliminary program:
meetings.embo.org/event/26-bac...

Faculty Position: Neurocomputation
Apply by December 1, 2025

WTI invites those from mathematical, computational, and related fields interested in working with experimentalists to develop new frameworks for understanding cognition.

🔗 wti.yale.edu/opportunities/faculty-neurocomputation

Fully funded NERC GW4+ PhD Opportunity - *Understanding The Spread of Antimicrobial Resistance by Migratory Birds*

Supervised by me, @stubearhop.bsky.social (Exeter) & Patricia Brekke (ZSL). Application deadline 8th January. Please get in touch for more info

www.findaphd.com/phds/project...

Don't miss out on our free virtual symposium (Dec. 12th) focused on microbial metabolites and their effects on the host.

Sponsors: @amiposts.bsky.social, Pendulum, & Liv (@zymoresearch.bsky.social)

Registrants will receive free memberships to Applied Microbiology International.

Details below 👇

We are back with new YBM sessions!
Abstract submission is open for our next YBM meeting on January 5th 2026.
Submit your abstracts here : t.co/W1qGraRpAc
Sign up for updates : t.co/O7XhxxSn2u
Speaker list of previous sessions can be found on our website: t.co/XBGYf9X4qQ

Happening now!

🚨 Soon at 15:30 EU (in 1h), Guillaume Salbreux (Geneva University) will present the talk

From active surfaces to evo-devo-mechanobiology

at the Population Dynamics Seminars.

sites.google.com/view/popdyn/

What is the most profitable industry in the world, this side of the law? Not oil, not IT, not pharma.

It's *scientific publishing*.

We call this the Drain of Scientific Publishing.

Paper: arxiv.org/abs/2511.04820
Background: doi.org/10.1162/qss_...

Thread @markhanson.fediscience.org.ap.brid.gy 👇

Strain displacement in microbiomes via ecological competition - Nature Microbiology Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.

Can we leverage bacterial competition for targeted replacement of harmful strains? Maybe! Our recent piece in @natmicrobiol.nature.com provides a theoretical framework and a set of experiments to show what it might take: www.nature.com/articles/s41...