Paulina Nuñez-Valencia's Avatar

Paulina Nuñez-Valencia

@paulinanunezv.bsky.social

PhD student - Machine Learning for Conservation. Dias&Frazer Lab @crg.eu with Mafalda Días and @jonnyfrazer.bsky.social

238 Followers  |  813 Following  |  1 Posts  |  Joined: 08.12.2024  |  1.5308

Latest posts by paulinanunezv.bsky.social on Bluesky

Applications are open for the @crg_eu PhD Programme! 20 fully funded positions — including one in our group through the Evolutionary Medical Genomics ITN.

Join us to develop deep generative models of cross-species data to tackle open questions in disease genetics.

www.crg.eu/en/content/t...

23.10.2025 11:00 — 👍 11    🔁 9    💬 0    📌 2

Check out our new preprint!
How can we get more out of existing protein/genome language models without retraining them?

26.05.2025 20:31 — 👍 7    🔁 2    💬 0    📌 0

Awesome paper. Simple post-hoc trick (averaging over homologs) with elegant evolution theory dramatically improves zero shot coding variant effect prediction in pLMs & actually delivers better results from the larger models (inverting the trend with raw likelihoods). 1/

26.05.2025 09:40 — 👍 48    🔁 9    💬 1    📌 1
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@cwjpugh.bsky.social at #VariantEffect25

22.05.2025 10:29 — 👍 19    🔁 8    💬 0    📌 0
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Proud supervisor moment! Next up at #VariantEffect25: Charles Pugh @cwjpugh.bsky.social, PhD student in Mafalda’s and my group, presents: From Likelihood to Fitness: Improving Variant Effect Prediction in Protein and Genome Language Models #AI #ProteinML

22.05.2025 10:10 — 👍 18    🔁 3    💬 0    📌 0
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A lovely summary of what we have learnt about scaling from ProteinGym -- Have we reached a performance plateau? More on this later in the week from @cwjpugh.bsky.social

21.05.2025 08:55 — 👍 4    🔁 2    💬 0    📌 0

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