With bioinformatics, we’re now measuring the fitnesses of millions of DNA fragments! This gets us data on whole genomes and is the first step toward big data for modeling genotype -> phenotype with AI/ML for microbial evolution. Link in comments.
🧬 + 🔢 = 📈 -> 🤖?
09.05.2025 00:34 — 👍 4 🔁 1 💬 1 📌 1
"Let's go do that"
A conversation with Astera resident Erika Alden DeBenedictis
Was so fun to talk with @asterainstitute.bsky.social resident and @pioneerlabs.bsky.social founder @erika-alden.bsky.social! Read our convo if you want to be inspired about the future of life, bioengineering, and engineered life on Mars
asterainstitute.substack.com/p/lets-go-do...
13.12.2024 14:03 — 👍 3 🔁 3 💬 1 📌 1
🏆 A Biologist’s Guide to Mars Dirt
Just add water
Check out 🏆A Biologist’s Guide to Mars Dirt, where we present a receipt for soluble Mars Regolith Media (sMRM) that best simulates what you’d get if you added water to Mars dirt.
Will anything grow in this media? Stay tuned!
💧+ 🪨 → 🌱 ?
open.substack.com/pub/pioneerl...
10.12.2024 17:27 — 👍 13 🔁 8 💬 0 📌 3
There's even more in the pipeline. Expect another post soon that describes how we plan to chemically simulate Mars!
20.11.2024 00:32 — 👍 1 🔁 0 💬 0 📌 0
The first turn of our engineering crank 🛠🧂
Beyond deletions: additive strain engineering and adaptation
In our most recent post we describe fragmenting a halophilic genome 🔪, building functional libraries 🪡 and selecting them 🤼 to find genes that measurably 📏 improved salt tolerance🛠🧂! Lab notebook links once more included if you want to dive into the details! open.substack.com/pub/pioneerl...
20.11.2024 00:32 — 👍 1 🔁 1 💬 1 📌 0
We can reliably measure salt tolerance 📏🧂
We have achieved Traction!
Our second post outlined our first measurement, where we link lab notebooks showing how we reliably quantify salt tolerance 📏🧂 . We also talk about several things that didn't work! pioneerlabs.substack.com/p/we-can-rel...
20.11.2024 00:32 — 👍 1 🔁 0 💬 1 📌 0
How to make a microbe for Mars, one step at a time
Our engineering roadmap 🚀🦠
Our first post outlined our roadmap, complete with benchmarks, measurements and engineering cranks! pioneerlabs.substack.com/p/how-to-mak...
20.11.2024 00:32 — 👍 1 🔁 0 💬 1 📌 0
Want to follow along as we engineer microbes for circular biomanufacturing in space? We're launching open science updates through our substack! ⬇️
20.11.2024 00:32 — 👍 7 🔁 2 💬 1 📌 0
Exploring workforce skills for Industry 5.0. We are a #HorizonEU initiative funded by EU HaDEA
https://bridges5-0.eu/
Synthetic Biologist, Protein and Genome Engineer, Microbe and Fungi Fan
www.billerbecklab.com
engineering biology for a more circular economy
Synthetic biologist @ANU, made in NZ
Scientist doing a PhD in synthetic and evolutionary microbiology with Tiffany Taylor and Thomas Gorochowski. Also interested in developmental biology, plants, and science communication/education. I like to make in media incl. DNA and code. He/him
Assistant Professor at the University of Washington - Chemical Engineering. Building technology and engineering biology with #XenoNucleicAcids at the Xenobiology Lab.
#XNA #SyntheticBiology #ChemBio #Biosynthesis #NucleicAcids #UW
A bioengineer who believes in an abundant future. Follow my writing on innovation at: https://gairiksachdeva.substack.com/
Biotech business development at Skyhook. Previously at Arbor Bio, Abata Tx, Silver Lab.
All views here and on Substack are my own.
Cofounder/CEO Octant
BoD Ginkgo Bioworks
Defense Science Board for Emerging Biotech
Fmr: Associate Professor, UCLA
co-founder and CEO at Ginkgo Bioworks
Former Chair of National Security Commission on Emerging Biotechnology
Protein engineer (Rosetta/ML/wet lab) working on a NewCo building targeted chemotherapy for solid tumours (esp. PDAC) using ADEPT — loops and buried polar groups are a feature, not a bug.
Postdoc at Marc Güell's lab at UPF Barcelona | Engineering the microbiome to understand (and treat) the skin 🦠 #SynBio | Alumni LPI (former CRI) & UniZar | 🇪🇸 🇫🇷 🇬🇧
More info: www.gnevot.xyz
Immunotherapy, CAR-T, Protein Design, Synthetic biology, Cell Signaling.
Head of Research Group | Structural Biochemistry | LIT
Leibniz Institute for Immunotherapy
https://lit.eu/our-scientists/dr-leo-scheller/
🇫🇷🇲🇽 Assoc. Prof. @SorbonneU Paris, in Biophysics | DNA nanotechnology 🧬 🤖Active Matter ⚙️🌊 | Microfluidics💧🔬| formerly @UTokyo 🍂 🇯🇵
Postdoc working on RNA Nanotech & MD simulations @uniheidelberg.bsky.social & MPIP. GROMACS wrangler, oxDNA developer, @molpigs.bsky.social podcast host, and all around weird lil guy.
Has been known to post about music and neat bugs found in the woods.
Research Scientist in ML+Bio | Stanford Ph.D. | Google X
I do SciML + open source!
🧪 ML+proteins @ http://Cradle.bio
📚 Neural ODEs: http://arxiv.org/abs/2202.02435
🤖 JAX ecosystem: http://github.com/patrick-kidger
🧑💻 Prev. Google, Oxford
📍 Zürich, Switzerland
Molecular Immunologist
TCRs, BCRs, and their ligands
Head of Immunology Discovery at BioMed X
Heidelberg, Germany and New Haven, CT
Synthetic biologist at Ginkgo working on Biosensors, CRISPR tools, etc.
My art is on Instagram @rishi.jain.art
DPhil student in the Engineered Biotechnology Group, University of Oxford. https://steel.ac/
ORCID: 0000-0002-2360-7150
Patent Examiner at European Patent Office, The Hague, NL. Professor of Biosystems Engineering and Control, Department of Bioengineering, Imperial College London, UK
09.05.2025 00:34 — 👍 0 🔁 0 💬 0 📌 1
