Anestis Tsakiridis

Postdoctoral Research Associate: Modelling Neural Crest Anomalies (mouse/human) - the Node The Liu lab is looking for a postdoc with a love of embryos and developmental biology! This post is part of an MRC-funded collaboration between Karen Liu’s lab at King’s College London and Marco Trizz...

Dev biologists! 3-yr postdoc position at King's, collaboration with Trizzino lab @marcotrizzino.bsky.social modelling CHD3 neural crest. We are looking for postdocs with mad embryology skills @the-node.bsky.social #developmental @ccrb27.bsky.social

thenode.biologists.com/jobs/postdoc...

Application deadline for up to 5 @mrc-lms.bsky.social postdoc positions in developmental epigenetics closes soon - don’t miss out! Positions across both experimental and computational projects. Come and join our fantastic team science community!

📣 Cilia Lab is growing 📣 - we have 2️⃣ open positions at @uoe-igc.bsky.social @edinburgh-uni.bsky.social for talented and motivated researchers interested in disease modelling & genetic therapies which target #RareRespiratoryDiseases at their root cause. 🧪🧪#ciliopathies #PrimaryCiliaryDyskinesia 1/4

Ecstatic to share our paper on nutrient signaling in the #EntericNervousSystem published in Nature! 🧪

We explored how neurons in the gut respond to basic nutrients that we typically ingest and tested whether they can distinguish between different nutrients 🔬

Check it out 👉 tinyurl.com/3vc756dv

Looking foward to the Northern(ish) Developmental Biology Meeting 2025 next week @sheffielduni.bsky.social! Thanks to the organisers @shaneherbert.bsky.social Raman Das @tsakiridis.bsky.social @kyracampbelllab.bsky.social

ENS aficionados, mark your calendars: the next symposium on enteric nervous system development, function and repair, will be held at KU Leuven from 7–10 April 2026. Excellent line up of speakers and the website is now live so for more details check: ens-leuven2026.eu ‪

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

Congrats Vicki!

Today’s speaker in our DRN external seminar series is Dr Sissy Wamaitha from the University of California, Los Angeles (UCLA)

Sponsored by the Physiological Society @physoc.bsky.social

Host: Stan Strawbridge
@stanleystrawbridge.bsky.social

All welcome!

🚨 New paper out in Development! 🚨

We show that donor embryonic stem cells (ESCs) reshape the developing mouse embryo, not just by what they signal, but where they push.

📄 doi.org/10.1242/dev....

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1/10🧵 New preprint! 🚀
We built a resource of 20 clonal human naïve pluripotent stem cell lines from 10 blastocysts. Explore embryo-to-embryo and clone-to-clone variation in one place.
👉doi.org/10.1101/2025.06.02.657331

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Today’s speaker in our DRN external seminar series is Dr Thorsten Boroviak (PDN, University of Cambridge) @pdncambridge.bsky.social , who will talk on early embryonic development in primates.

Host: Anestis Tsakiridis @tsakiridis.bsky.social

All welcome!

Congratulations to Dr Claire Turner @molmicrosheffield.bsky.social and DRN's Professor Ivana Barbaric on their excellent talks in the University of Sheffield @sheffielduni.bsky.social School of Biosciences Inaugural Lecture series today.

www.sheffield.ac.uk/biosciences/...

www.thebarbariclab.com

The UK Stem Cell Network has just launched registrations for the meeting in September: Find out more by visiting ukstemcellnetwork.org/2025-confere...

Early-bird deadline is 23rd June

Indeed, it was great to catch up again!

Fantastic to see @tsakiridis.bsky.social's excellent work on Neuroblastoma and to finally chat some science with a social acquaintance from my PhD years some 20 years later 😮

Such a pleasure to host you for the @uoe-igc.bsky.social seminar series @tsakiridis.bsky.social. It was great to hear about your latest exciting and impactful science and it was great to catch up! Thank you for visiting us and bringing the beautiful weather!

This is insane. Labour is making the very same mistake the Tories made but in a more catastrophic way. A left-leaning party adopting an ultra-right fascist agenda: what could go wrong?

Always a pleasure to return to Edinburgh and visit @uoe-igc.bsky.social, I had a fantastic day discussing science and meeting old and new friends. Many thanks to @hannahlong.bsky.social for the warm hospitality-even the sky was blue!

Altering metabolism programs cell identity via NAD+-dependent deacetylation | The EMBO Journal imageimageHow alterations in cell metabolism translate into specific developmental gene programs remains a major question. This study shows that forcing OXPHOS metabolism reprograms mouse embryonic stem cells (ESCs) to a more inner cell mass (ICM)-...

How does metabolism act through generic chromatin modifiers promote specific cellular states? Simultaneous modification of transcription factors and chromatin, enhancing epigenetic signal to noise ratios.
www.embopress.org/doi/full/10....

Interphase cell morphology defines the mode, symmetry, and outcome of mitosis During tissue formation, dynamic cell shape changes drive morphogenesis while asymmetric divisions create cellular diversity. We found that the shifts in cell morphology that shape tissues could conco...

My first post on Bluesky! Very excited to share our work just published in @science.org. We find that “Interphase cell morphology defines the mode, symmetry, and outcome of mitosis” - in angiogenesis and other tissues! www.science.org/doi/abs/10.1... www.science.org/doi/abs/10.1...

Kindly sponsored by the @biologists.bsky.social

1 month left to register for this year's @bsdb.bsky.social Northern(ish) England Developmental Biology Meeting here in Sheffield (10th of July). We have a great speaker line-up and available oral presentation slots for PGRs/ECRs. For registration/details see: onlineshop.shef.ac.uk/product-cata...

Purinergic signalling and calcium dynamics: potential drivers in the onset of coordinated intestinal motility in human fetal development https://www.biorxiv.org/content/10.1101/2025.04.17.649306v1

Don’t miss this exciting opportunity. Feel free to reach out with any question.
PIs, please share

In vivo sonic hedgehog pathway antagonism temporarily results in ancestral proto-feather-like structures in the chicken The Sonic Hedgehog (Shh) pathway is a key regulator of feather development. These authors show that in vivo Shh inhibition during early chicken embryogenesis temporarily results in unbranched and non-...

🚨🐣 Our new paper is out @plosbiology.org! Sonic hedgehog inhibition transforms feathers into ancestral protofeathers-like structures. These units then recover after hatching, highlighting their remarkable developmental robustness! @lanevol.bsky.social 🧪

journals.plos.org/plosbiology/...

Congrats Rory!

Science under siege: protecting scientific progress in turbulent times As Editors-in-Chief of The Company of Biologists' journals, we have been watching with growing concern the policy changes in the United States of America (USA) and the challenges that these are creati...

Science under siege: protecting scientific progress in turbulent times

journals.biologists.com/dev/article/...

Looking forward to hosting Sarah McClelland @mcclellandlab.bsky.social, @qmbci.bsky.social today 1-2 pm, Medical School LT3, F Floor @drn-sheffield.bsky.social @sheffielduni.bsky.social