Center for Systems Biology Dresden

#GenAI meets perception psychology for better super-resolution microscopy 🤩 Fig.1 says it all! 😎 Fantastic collaboration with @casusscience.bsky.social - work of @zuseschoolsecai.bsky.social students @csbdresden.bsky.social - out now onlinelibrary.wiley.com/doi/10.1002/...

24.07.2025 19:31 — 👍 1    🔁 2    💬 0    📌 0

Morphogen gradients are regulated by porous media characteristics of the developing tissue Summary: Image-based 3D modeling of pore-scale extracellular space geometries of the developing zebrafish embryo reveals that the Fgf8a morphogen gradient is regulated by the porous media characterist...

⚡️Advanced Computing ❤️ laboratory experiments ➡️ an unbeatable combination to unlock the secrets of biology! Together with the Brand lab @tudresden.bsky.social we @csbdresden.bsky.social discovered a simple mechanism how tissue geometry controls growth: journals.biologists.com/dev/article/...

14.07.2025 16:45 — 👍 20    🔁 7    💬 2    📌 2

Integrating Odeint Time Stepping into OpenFPM for Distributed and GPU Accelerated Numerical Solvers We present a software implementation integrating the time-integration library Odeint from Boost with the OpenFPM framework for scalable scientific computing. This enables compact and scalable codes fo...

Our scientific computing framework #OpenFPM now has multistage and adaptive time integrators that scale to distributed CPU clusters and GPUs! Happy supercomputing! @tudresden.bsky.social @csbdresden.bsky.social @mpi-cbg.de preprint: arxiv.org/abs/2309.05331

10.07.2025 07:34 — 👍 4    🔁 3    💬 0    📌 0

We are looking for a new Max Planck Director in Biomedical #AI here at @csbdresden.bsky.social @mpi-cbg.de. Excited and looking forward!

27.06.2025 08:16 — 👍 0    🔁 0    💬 0    📌 0

🐠🦠Why can’t bacteria swim like fish?
At microscopic scales, physics changes — viscosity rules! Researchers at our institute study how microbes like E. coli overcome this challenge with clever strategies like run-and-tumble.

Watch our new video:

youtu.be/drwCRRD7CGY?...

17.06.2025 07:45 — 👍 41    🔁 18    💬 3    📌 1

Now #published @cp-cellsystems.bsky.social: "Impossible ecologies: Interaction networks and stability of coexistence in ecological communities" doi.org/10.1016/j.cels.2025.101297!
With @yumeng0806.bsky.social, @szhorvat.bsky.social, Carl Modes @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social.

17.06.2025 11:49 — 👍 22    🔁 9    💬 1    📌 0

Formeln des Lebens Künstliche Intelligenz mit physikalischem Vorwissen soll biologische Vorgänge berechenbar machen

Formulas of Life: article of the @maxplanck.de on the research of Ivo Sbalzarini @mosaicgroup.bsky.social. Article in German language: www.mpg.de/24841408/ki-...

12.06.2025 08:58 — 👍 5    🔁 3    💬 0    📌 0

Wie kann Künstliche Intelligenz in der Biomedizin helfen? Biologie und Medizin sind eng verknüpft. Künstliche Intelligenz kann dabei in vielen Fragen helfen. Was ist zu beachten?

Ivo Sbalzarini was interviewed by German science radio @detektorfm.bsky.social and explains our research @csbdresden.bsky.social @mpi-cbg.de @tudresden.bsky.social to a general audience (in German only):

detektor.fm/wissen/forsc...

12.06.2025 06:58 — 👍 4    🔁 2    💬 0    📌 0

A Transparent and Efficient Extension of IceT for Parallel Compositing on Non-Convex Volume Domain Decompositions The IceT library is widely used for parallel compositing but does not support non-convex volume domain decompositions. We provide a backward-compatible extension of IceT to handle non-convex domain de...

🔥Just out @EGPGV’25: Parallel visualization of distributed volume data for non-convex decompositions! @csbdresden.bsky.social @tudresden.bsky.social @mpi-cbg.de And the best: code is contributed upstream 🤩 diglib.eg.org/items/3aed38...

08.06.2025 09:44 — 👍 3    🔁 2    💬 0    📌 0

Now #published in Phys. Rev. Lett. as an Editors' Suggestion: "Mechanics of poking a cyst" - the first paper from the PhD work of @zhaoshh.bsky.social.

journals.aps.org/prl/abstract...

@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social

05.06.2025 15:01 — 👍 25    🔁 5    💬 2    📌 1

Funding for Mathematician from Knut and Alice Wallenberg Foundation Danai Deligeorgaki from the KTH Royal Institute for Technology in Stockholm will spend postdoctoral time with mathematicians at MPI-CBG.

Funding for Danai Deligeorgaki from the Knut and Alice Wallenberg Foundation. She will spend her postdoctoral time with @aidadoesmath.bsky.social and Heather Harrington @math-mpicbg.bsky.social at the @mpi-cbg.de & @csbdresden.bsky.social. Congratulations! 🎉 www.mpi-cbg.de/news-outreac...

04.06.2025 14:17 — 👍 6    🔁 2    💬 0    📌 0

MPI-CBG participates in Dresden 5K running event Nine teams ran REWE Team Challenge Dresden 2025

Thirty-six institute staff members in nine tems participated in the REWE Team Challenge Dresden on Wednesday evening, May 28. Congratulations to all participants! 🎉 www.mpi-cbg.de/news-outreac...

04.06.2025 07:10 — 👍 15    🔁 5    💬 0    📌 1

SHARK: web server for alignment-free homology assessment for intrinsically disordered and unalignable protein regions Abstract. Whereas alignment has been fundamental to sequence-based assessments of protein homology, it is ineffective for intrinsically disordered regions

Are you looking for homologous sequences but alignments do not seem to work? SHARK is available as a webserver: compare sequences or search against precomputed IDR datasets: bio-shark.org @narjournal.bsky.social @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social
doi.org/10.1093/nar/...

28.05.2025 21:24 — 👍 21    🔁 13    💬 2    📌 0

Picture of the PIs of TUD's Clusters of Excellence and Cluster of Excellence Initiatives beeing happy.

Picture of TUD's Rector Prof. Ursula Staudinger during the announcement of the funding decision of the DFG.

Picture of cheering guests in the ballroom of the Rectorate Building.

Picture of TUD's Rector Prof. Ursula Staudinger and cheering guests in the ballroom of the Rectorate Building.

Outstanding success: 🎉 #TUDresden shines with 5 Clusters of Excellence. @dfg.de & @wissenschaftsrat.de announced that decision today. TUD has impressively proven its claim to be a top university for the 21st century.
ℹ️ tu-dresden.de/tu-dresden/n...

22.05.2025 16:54 — 👍 84    🔁 31    💬 8    📌 8

Aida Maraj selected as fellow of the Elisabeth-Schiemann-Kolleg  Mentoring network of the Max Planck Society for women in the natural sciences

Aida Maraj @aidadoesmath.bsky.social selected as fellow of the Elisabeth-Schiemann-Kolleg @maxplanck.de. Congratulations! 🎉 www.mpi-cbg.de/news-outreac...

09.05.2025 13:49 — 👍 14    🔁 2    💬 0    📌 0

Deep learning tools predict variants in disordered regions with lower sensitivity - BMC Genomics Background The recent AI breakthrough of AlphaFold2 has revolutionized 3D protein structural modeling, proving crucial for protein design and variant effects prediction. However, intrinsically disorde...

Deep learning tools predict variants in disordered regions with lower sensitivity. Just published by FedericaLuppino, @swlenz.bsky.social and WillisChow @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social bmcgenomics.biomedcentral.com/articles/10....

16.04.2025 21:43 — 👍 7    🔁 3    💬 1    📌 0

"Unbuckling" in a minimal model of cell monolayers under compression: work by Chandraniva Guha Ray and @lepuslapis.bsky.social @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social now highlighted as an Editors' Suggestion by Physical Review Letters!

doi.org/10.1103/PhysRevLett.134.118402

25.03.2025 16:57 — 👍 18    🔁 6    💬 1    📌 0

SHARK‐capture identifies functional motifs in intrinsically disordered protein regions Increasing insights into how sequence motifs in intrinsically disordered regions (IDRs) provide functions underscore the need for systematic motif detection. Contrary to structured regions where moti...

Identifying functional motifs in disordered regions is challenging. We gave it a try. Check out SHARK-capture, an alignment-free method to detect SLiMs. Congrats Chi Fung Willis Chow @swlenz.bsky.social et al. @mpi-cbg.de @csbdresden.bsky.social @poldresden.bsky.social doi.org/10.1002/pro....

18.03.2025 20:05 — 👍 36    🔁 17    💬 2    📌 1

Happy International Women’s Day!

08.03.2025 08:05 — 👍 31    🔁 8    💬 1    📌 0

New #preprint: "Euler buckling on curved surfaces" arxiv.org/abs/2503.04303

@zhaoshh.bsky.social and I ask the question that Euler left open: How does an elastic line buckle within a (general) curved surface?

@mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social

07.03.2025 08:38 — 👍 28    🔁 5    💬 2    📌 0

New #preprint: "A model for boundary-driven tissue morphogenesis" arxiv.org/abs/2503.03688.

A great collaboration with @danielalber.bsky.social @zhaoshh.bsky.social, Alexandre Jacinto, Eric Wieschaus, Stas Shvartsman.

@flatironinstitute.org @mpipks.bsky.social @mpi-cbg.de @csbdresden.bsky.social

06.03.2025 09:51 — 👍 53    🔁 15    💬 1    📌 2

Hello! The CSBD is now sharing news on @bsky.app 🦋

26.02.2025 12:57 — 👍 10    🔁 4    💬 0    📌 0