Oscar Marcelo Lazo's Avatar

Oscar Marcelo Lazo

@omlazo.science.bsky.social

Broad-spectrum neurobiologist, cancionista, & escribidor de brocha gorda. Dad of three humans, married to their unfathomable mum. I ask questions to neurons and brains at the UCL Queen Square Institute of Neurology 🇬🇧 and Universidad San Sebastián 🇨🇱.

226 Followers  |  185 Following  |  73 Posts  |  Joined: 20.09.2023  |  1.8997

Latest posts by omlazo.science on Bluesky

Velan? 😂

15.10.2025 21:10 — 👍 1    🔁 0    💬 0    📌 0

Ok, I get it.

15.10.2025 21:09 — 👍 1    🔁 0    💬 0    📌 0

Don't quite get the difference between methods and protocols. Could you please expand?

15.10.2025 17:40 — 👍 0    🔁 0    💬 1    📌 0

This may be an unpopular thing to say today, but Venezuela deserved a much better political opposition — and now it’s harder than ever for them to get one.

10.10.2025 20:00 — 👍 0    🔁 0    💬 0    📌 0
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127th British Neuropathological Society meeting Annual Scientific Meeting of the British Neuropathological Society, 28–30 Jan 2026 at The View, Royal College of Surgeons of England, London.

Annual Scientific Meeting of the British Neuropathological Society, 28–30 Jan 2026 at The View, Royal College of Surgeons of England, London.

www.dementiaresearcher.nihr.ac.uk/event/127th-...

09.10.2025 12:06 — 👍 1    🔁 2    💬 0    📌 0

La democracia liberal patas pa arriba: un comercio no puede ponerle a sus clientes una regla de convivencia básica, como no portar armas visiblemente en el interior del súper, porque viola sus derechos constitucionales. ¡Jolín!

09.10.2025 22:00 — 👍 0    🔁 0    💬 0    📌 0
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EIPR1 variants cause a neurodevelopmental disorder with endolysosomal and dense core vesicle defects Abstract. EIPR1 (EARP-interacting protein 1, formerly known as TSSC1) is a WD40-domain protein that interacts with the EARP (endosome-associated recycling

Excited to share our latest manuscript by @saikat2025.bsky.social and an international team, reporting variants in the EARP- and GARP-interacting protein EIPR1 associated with a neurodevelopmental disorder. Will send you the PDF if you can’t access the article: academic.oup.com/brain/articl...

08.10.2025 15:33 — 👍 11    🔁 4    💬 0    📌 0
31 Minutos: Tiny Desk Concert
YouTube video by NPR Music 31 Minutos: Tiny Desk Concert

Latinoamérica en El Tiny! youtu.be/UEqTIwRrWvA?...

06.10.2025 21:59 — 👍 0    🔁 0    💬 0    📌 0
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Join us today for a new session of our Journal Club on Psychology & Neuroscience —we are having a special guest, @tonchimatta.bsky.social, who comes to discuss her favourite bit of neuroscience: brain-machine interfaces and their potential.

30.09.2025 11:21 — 👍 1    🔁 0    💬 0    📌 0
kirkus review: SCIENCE UNDER SIEGE
HOW TO FIGHT THE FIVE MOST POWERFUL FORCES THAT THREATEN OUR WORLD

by Michael E. Mann & Peter J. Hotez ‧ RELEASE DATE: Sept. 9, 2025

A necessary and propulsive argument that offers optimism in the face of one of the world’s most destructive forces.

Pursuing science and truth in the age of disinformation.

On the tail of a historic deadly pandemic, in the midst of a climate crisis that threatens the world, perhaps the greatest danger is the overwhelming rise of disinformation that threatens to crush and diminish science that might save us. With that, two renowned scientists—climatologist Mann and pediatrician and global health expert Hotez—who are veterans of the disinformation wars have come together to create a work that seeks to provide a way out. The authors identify what they call “the p’s”—five key forces creating a dangerous modern realm of anti-science: “the plutocrats, the authoritarian petrostates (assisted by polluters and the politicians who advocate for them), the ‘pros’ who use their professional (or in some cases scholarly) credentials to deceive or promote unsupported contrarian views, the propagandists who amplify them on social media and other venues, and, increasingly, the press, including even the mainstream press.” The narrative reveals, in compelling detail, how these forces weave a complicated web of public deception and political danger in the face of some of humanity’s greatest challenges. With clear-eyed prose moving through chapters that explain each of these actors, the authors provide a clear, persuasive road map to fight back against the forces that diminish and dismiss science. The result is an empowering work in a world that can often feel lost to untruths. “While there is urgency—unlike any we’ve ever known—there is still agency,” they write. “We can still avert disaster if we can understand the nature of the mounting anti-science threat and formulate a strategy to counter it.”
A necessary and pro…

kirkus review: SCIENCE UNDER SIEGE HOW TO FIGHT THE FIVE MOST POWERFUL FORCES THAT THREATEN OUR WORLD by Michael E. Mann & Peter J. Hotez ‧ RELEASE DATE: Sept. 9, 2025 A necessary and propulsive argument that offers optimism in the face of one of the world’s most destructive forces. Pursuing science and truth in the age of disinformation. On the tail of a historic deadly pandemic, in the midst of a climate crisis that threatens the world, perhaps the greatest danger is the overwhelming rise of disinformation that threatens to crush and diminish science that might save us. With that, two renowned scientists—climatologist Mann and pediatrician and global health expert Hotez—who are veterans of the disinformation wars have come together to create a work that seeks to provide a way out. The authors identify what they call “the p’s”—five key forces creating a dangerous modern realm of anti-science: “the plutocrats, the authoritarian petrostates (assisted by polluters and the politicians who advocate for them), the ‘pros’ who use their professional (or in some cases scholarly) credentials to deceive or promote unsupported contrarian views, the propagandists who amplify them on social media and other venues, and, increasingly, the press, including even the mainstream press.” The narrative reveals, in compelling detail, how these forces weave a complicated web of public deception and political danger in the face of some of humanity’s greatest challenges. With clear-eyed prose moving through chapters that explain each of these actors, the authors provide a clear, persuasive road map to fight back against the forces that diminish and dismiss science. The result is an empowering work in a world that can often feel lost to untruths. “While there is urgency—unlike any we’ve ever known—there is still agency,” they write. “We can still avert disaster if we can understand the nature of the mounting anti-science threat and formulate a strategy to counter it.” A necessary and pro…

book cover

book cover

#ScienceUnderSiege: How to Fight the Five Most Powerful Forces that Threaten Our World
by @peterhotezmdphd.bsky.social & yours truly,
comes out one week from today! 🙂
Preorder now:
Barnes & Noble: www.barnesandnoble.com/w/science-un...
Publisher: www.hachettebookgroup.com/titles/micha...

02.09.2025 12:18 — 👍 63    🔁 29    💬 3    📌 4
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Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar.

Lo ves aquí: pro.amorporlamarca.com/direct-surve...

13.08.2025 21:12 — 👍 2    🔁 2    💬 0    📌 0
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Atención chilenos, estamos haciendo un estudio narrativo de emociones evocadas por los candidatos a la presidencia. Ayer estuvimos presentándolo en @meganoticiascl.bsky.social y sigue abierto para que todos puedan evaluar a un candidato al azar.

Lo ves aquí: pro.amorporlamarca.com/direct-surve...

13.08.2025 21:12 — 👍 2    🔁 2    💬 0    📌 0
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La presencia de Hiroshima | Editorial El 80 aniversario de la destrucción de la ciudad japonesa advierte contra la actual frivolidad global sobre la amenaza nuclear

Editorial | "Las imágenes y los relatos del horror de Hiroshima y Nagasaki no son una conmemoración histórica más: sirven como recuerdo constante del daño existencial que la humanidad puede infligirse a sí misma"

06.08.2025 08:23 — 👍 27    🔁 16    💬 4    📌 3

Random chat last night...

— Dad, I'm not vaccinating. They say the HPV vaccine is the most painful one!
— Do you know what a papilloma is?
— No...
— A cause of cancer
— x___x
— A type of cancer that use to cause a lot of trouble and now you can avoid just getting vaccinated.
— Ok

05.08.2025 14:06 — 👍 0    🔁 0    💬 0    📌 0
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Tengo que hacer algunas clases este semestre. Afortunadamente son algunas de las cosas que más me entusiasman en el mundo, así que simplemente espero poder transferir algo de ese mismo entusiasmo.

¡Se viene el segundo semestre!

01.08.2025 15:17 — 👍 0    🔁 0    💬 0    📌 0
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I've been culturing intact explants of embryonic mouse basal forebrain. It's a pretty cool way to model interactions between the different BFN populations in vitro, both in physiology and disease, specially in Alzheimer's where these neurons are particularly vulnerable.

[Confocal— DAPI+Phalloidin]

31.07.2025 16:03 — 👍 1    🔁 0    💬 0    📌 0
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This Thursday 31st/July at 3.30 pm we have another session of our Journal Club on Psychology and Neuroscience. This month we are led by Prof. @pauladagnino.bsky.social to discuss mental health outcomes monitoring in the public system.

Join us!

28.07.2025 15:29 — 👍 1    🔁 0    💬 0    📌 0

Impaired BDNF-TrkB trafficking and signalling in Down syndrome basal forebrain neurons https://www.biorxiv.org/content/10.1101/2025.07.15.664857v1

19.07.2025 00:15 — 👍 1    🔁 1    💬 0    📌 0
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For Epistemic Respect – Against Reviewer 2 - Impact of Social Sciences Gorgi Krlev & Andre Spicer draw on an encounter with reviewer 2 and the subsequent twitterstorm, to explain what epistemic respect means and how to uphold it.

I came across this concept today and I liked this blog post on epistemic respect and peer-review: blogs.lse.ac.uk/impactofsoci...

08.07.2025 23:46 — 👍 0    🔁 0    💬 0    📌 0

Coming to London on a summer Saturday—when Pride celebrations were in full swing, and everyone was out with friends in all sorts of playful attire—has been absolutely vivifying!

05.07.2025 23:21 — 👍 1    🔁 0    💬 0    📌 0
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Tomorrow!

25.06.2025 14:41 — 👍 0    🔁 0    💬 0    📌 0

I grew up one little bit today.

I'm going back to the lab in London in a couple of weeks, and instead of booking a bed in a noisy backpackers' hostel as usual, I evolved to booking myself a room in a proper family-run hotel next door.

Yeahp... getting old.

23.06.2025 13:37 — 👍 1    🔁 0    💬 0    📌 0
An intriguing role of repeat-element RNAs in nerve injury repair - Nature Reviews Neuroscience A polyA-tail-directed RNA sequencing approach that was used to investigate transcriptomic changes in dorsal root ganglia following nerve crush revealed unexpected upregulation of a specific set of B2-...

🙏 to editor Sian Lewis for this @natrevneuro.nature.com highlight on our recent paper

www.nature.com/articles/s41...

07.06.2025 09:44 — 👍 4    🔁 3    💬 0    📌 0
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Today, in news that surprise no one...

www.nature.com/articles/d41...

27.05.2025 11:34 — 👍 52    🔁 19    💬 1    📌 1
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Antisense oligonucleotide jacifusen for FUS-ALS: an investigator-initiated, multicentre, open-label case series The findings suggest the safety and possible efficacy of jacifusen for treating FUS-ALS. The efficacy of jacifusen is being further evaluated in an ongoing clinical trial.

True that the promising story about jacifusen still requires more data to weight its impact in the real world, but I can't help thinking about the 16-y.o. kid with ALS that after a year of treatment is breathing again and recovering movement. Unprecedented progress! www.thelancet.com/journals/lan...

27.05.2025 02:45 — 👍 2    🔁 0    💬 0    📌 0
Post image 22.04.2025 20:44 — 👍 0    🔁 0    💬 0    📌 0

I feel you. I hope you comprehend.

15.03.2025 19:03 — 👍 0    🔁 0    💬 0    📌 0

😂 Qué talento.

07.03.2025 17:15 — 👍 1    🔁 0    💬 0    📌 0

If I were an elected Dem today, here’s what I’d be doing:

- Not cooperating with anything administration wants to do. No bailing the GOP out. Shut it down.

- Daily fireside chats explaining how/why I’m fighting.

- Calling them fash.

- Attending protests. Calling for protests (at their homes?)

01.03.2025 22:37 — 👍 645    🔁 157    💬 14    📌 11
National Institutes of Health (NIH) Official website of the National Institutes of Health (NIH). NIH is one of the world's foremost medical research centers. An agency of the U.S. Department of Health and Human Services, the NIH is the ...

Actually, if I go higher up the nih.gov website doesn't work either. :/

01.03.2025 21:14 — 👍 1    🔁 0    💬 1    📌 0

@omlazo.science is following 20 prominent accounts