Andrii Kozytskyi

Zoom-ins help uncover the fine structure of these crowded regions — a great example of the complexity of natural mixtures captured by NMR.

The region between 3.0–5.3 ppm is packed with signals from sugars like glucose and fructose.
You can also spot additional small molecules — amino acids, other organic acids, and possibly traces of aroma compounds — especially in the aliphatic region (0.5–2.5 ppm). 👇🧵

🍋 ¹H NMR of Lemon Juice
Freshly squeezed science!
This proton NMR spectrum of lemon juice reveals a rich mixture of natural metabolites. The intense multiplets around 2.6–2.8 ppm are from citric acid, the dominant organic acid in lemon.

#NMR #nmrchat #chemistry 👇🧵

My standard speed on this QNP-equipped Bruker is 100–150 routine ¹H spectra per hour (not ideal quality, of course — Z1 + Z2). Most folks don’t believe me 🤣

UPD ✅: The correct answer is C. The methyl group appears as a doublet, indicating coupling to a CH (eliminating structure A). The aldehyde signal is also a doublet with ³J = 1.5 Hz, indicating coupling to a CH (eliminating structure B).

It’s #NMRweekend ⁉️🧲 Write your answers in the comments section 👇. Note: This is an experimental spectrum. The explanation for the challenge will be published in a few days 😉.
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Oh. My. God.
#fluorine #spin #coupling #nmr #nmrchat

Spin coupling of fluorine to 4 chemically inequivalent Hydrogens

dddd )

Fluorine in bicyclic molecules looks mind blowing 🤯.
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Multiplet of the week 🧲 ᗑ. This particular proton has four couplings to the ¹H nuclei of two diastereotopic CH₂ groups (³J = 4.95, 5.66, 6.00, and 7.28 Hz) and a ³J coupling of 6.63 Hz to the methyl protons.

#nmr #nmrchat #spin #coupling #chemistry #organicchemistry #spectroscopy

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Just insane 🤯. MNova calculated it as “m” 🙂. But I didn’t give up and extracted all couplings separately 👌. Its CH signal at the chiral centre bonded to 2XCH₂ and CH₃ 🤌🤌🤌
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When my cat wants attention, he just lies down on my laptop while I’m working. )
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Damn that’s true 🤣🤣🤣
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nmr challenge

Analytical and Bioanalytical Chemistry, NMR Challenge, by Andrii V. Kozytskyi @nmrspectroscopy.bsky.social & Volodymyr V. Tymoschuk #Enamine Substituted piperidine challenge, submit your answer for a chance to win a Springer book up to €100 link.springer.com/article/10.1... #NMRchat #NMR 🧲

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My colleague is definitely having fun with his 3D printer) #nmr #nmrchat @brukercorporation.bsky.social

Ferromagnetic sample and its spectrum 👌
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🧲🧐 @uea-nmr.bsky.social bsky.app/profile/nmr9...

An awful sample with not that bad ¹H 🤷🏻‍♂️
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Me like 🤔😕😐🤷🫤😵‍💫💫🤣

The sample to illuminate the lab with.
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)))

Fast 13-carbons are dope 😎

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Love luminescent samples #nmr #nmrchat