IBD Doctor

Pat Bagley, Salt Lake Tribune
Short list for the Pulitzer
@PatBagley

Two panel cartoon. How it started: masked man beating Police Officer at the Capitol. How it’s going: identical masked man with ICE badge beating Statue of Liberty.

Remove ICE and CBP funding until real changes are made.
With apologies, I can’t find the artist to credit.

Mamdani: "I speak of Renee Good, whose final words to the man who murdered her were, 'I'm not mad at you.' I speak of Alex Pretti who died as he lived, caring for the stranger. ICE shot him bc he did something they could never fathom ... let us offer a new path: one of defiance through compassion."

a cartoon dog is sitting at a table in front of a fire with the words it 's fine everything is fine ALT: a cartoon dog is sitting at a table in front of a fire with the words it 's fine everything is fine

It's fine (as long as the patient happens to have a -80C freezer at home)

This moment is bringing out the best in some of us (like this speaker) and bringing out the worst in others of us. This is a time for choosing to live a life that you're proud of, or not. ❤️

It makes you wonder whether homeschooling is dangerous to society.

@scientificdiscovery.dev Hi, I am creating a new version of my free online MOOC, and would like to use this picture, of which you have the copyright. Is it ok if I put it in a slide?

Incentive sugar ($$) needed. Kids from age 5 onward need to register with one club each July. The club gets credit for each year they develop a player. @ussoccer.com solidarity payments for each year in the top 1000, top 150, each US cap. Divided among the development clubs by years of credit.

Oh look, according to Peter Attia MD “pussy is low carb” something that is totally normal for a doctor to say to Epstein, who had previously been convicted of procuring a child for prostitution

RVA Specialist At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted an...

I’m hiring! 🎉 I’m building out my team and looking for someone who enjoys working in R (tidyverse), is comfortable with Git, and is excited about data. 🤓

#rstats #tidyverse #datascience

roche.wd3.myworkdayjobs.com/roche-ext/jo...

It is more that
1) The Lancet editor insists it was the right thing to do, and would publish it again
2) The Lancet editorial board has a weird ideas about "free speech" and "controversial ideas" being "canceled"
3) Widely recognized as a compliant path for industry to get papers out quickly

Fraud Behind the MMR Scare | Immunize.org BMJ Calls Wakefield’s Study Linking MMR Vaccine to Autism ‘Fraudulent’ In a special series of articles published in 2011 by BMJ, author Brian Deer exposes the data behind claims that launched a worldw...

Why we should avoid reading, quoting, or in any way supporting The Lancet medical journal. @elisabethbik.bsky.social
The fraud underlying the Wakefield anti-MMR publication in the Lancet. Follow the money. A full explication from the BMJ here:

www.immunize.org/clinical/vac...

Please Switch to Python Or R. Or Anything. Just Not Stata, SAS, SPSS, or MATLAB.

Abigail Haddad back with yet again another banger of a blog post that everyone who is still hanging on to STATA, SAS, SPSS, MATLAB, etc needs to read and internalize.

Especially relevant for #civictech

open.substack.com/pub/presento...

nycOpenData: A unified R interface to NYC Open Data APIs Discover nycOpenData, an R package offering tidy, reproducible access to NYC Open Data APIs for teaching, research, and civic data analysis.

🆕 New guest post on the blog!

Discover nycOpenData, an R package that provides tidy, reproducible access to NYC Open Data APIs — perfect for teaching, research, and civic data analysis.

statsandr.com/blog/nycopen...

#RStats #OpenData #DataScience #ReproducibleResearch #CivicTech

That's 62.2 degrees celsius for the rest of the world.

Treating Refractory IBD Slides from the Crohn's and Colitis Congress 2026

Slides from today's talk on approaches to refractory #IBD at the Crohn's and Colitis Congress can be found here - please share!
speakerdeck.com/higgi13425/t...
@crohnsandcolitisau.bsky.social @crohns-disease.org.uk @ccyanetwork.bsky.social @crohnscolitisfdn.bsky.social @crohnscolitisca.bsky.social

Examples of how to use the new futurize package

Oooh love this. Easiest way to parallelise anything in #rstats. Just add futurize() to your favourite function call

www.jottr.org/2026/01/22/f...

Thanks @henrikbengtsson.bsky.social HT @rstats.blaze.email

Is anyone here an expert on #rstats ellmer structured data?

It works when I define the JSON schema of an object A containing an array of object B, but not when I read object B from JSON schema and use type_object and type_array to set up object A.

Reprex: gist.github.com/debruine/d35...

main image for Scaling Up Data Analysis in R with Arrow R Consortium webinar

R Consortium webinar: Scaling up data analysis in R with Arrow. Learn larger-than-memory workflows, why Parquet matters, and where DuckDB fits—w/ Dr Nic Crane (Arrow R maintainer; Apache Arrow PMC). Register: r-consortium.org/webinars/sca... #rstats #arrow @niccrane.bsky.social

Having a reasonable (not overpowering) Bayesian prior from adult studies would actually make the pediatric studies small enough and affordable enough to actually get done. Rather than the complete absence of data in pediatrics that we have now.

But what we do now (not great) is to do the adult study, decide the pediatric market is too small to do a study at all in kids, and then have pediatricians spending their days appealing to insurance to get a drug covered that has never been studied (in a RCT) in kids.

The adult prior can dominate (probably too much). It would be reasonable (the devil is in the details) for the FDA to limit priors to the equivalent of 100 adults (pick your favorite number) so as not to overpower actual data in children.

(1) at least adults are the same species as human children, so we are pretty confident (2) Decades of experience have shown that drugs that work in adults also work in children. But there is an issue when 1700 adults were studied, and the difference between drug and placebo is large.

HHS Gave a $1.6 Million Grant to a Controversial Vaccine Study. These Emails Show How That Happened Two Danish researchers faced accusations of “questionable research practices” as RFK Jr.’s top appointees made their study a “funding priority.”

How sad is this? The CDC closed its FOIA office, so this story could only be published because a Danish journalist provided Rolling Stone with the documents, after obtaining them through a freedom of information request to the University of Southern Denmark

www.rollingstone.com/politics/pol...

Agreed. I think that there is a niche for the "feeder league" academic model - as in world soccer/English football, the revenue/salaries in the Dutch league are lower, so they find talented young players, put them in positions of responsibility, and know that some will leave for the Prem in England.

Must they though?
Some will definitely train up at OUP and then leave for more $$ elsewhere. Others (a minority) will value the position for other reasons, if you treat them well.

Reported Executive Compensation Examples
Nigel Portwood (Former CEO): Around $1.7 million.
Tim Fulton (Chief Transformation Officer): Around $1.038 million.
Fathima Dada (MD Education): Around $1.01 million.
David Clark (MD Academic): Around $913,000.

Nitazoxanide Is Effective Therapy For Norovirus Gastroenteritis After Chemotherapy and Hematopoietic Stem Cell Transplantation (HSCT) Norovirus infection is a major cause of nonbacterial gastroenteritis and is a self-limited infection in immunocompetent patients. However, in immune compro

It is not terribly common, but I have a few patients who really have trouble clearing norovirus. Not sure if it is underlying host factors or their #IBD meds. In cases with notable weight loss I will occasionally use nitazoxanide off label. ashpublications.org/blood/articl...

I would like to see how well this works in small bowel Crohn's with standard immunosuppression. Would be nice to protect these folks from summer and winter waves of noro #IBD

An oral, mucosal norovirus vaccine given to breastfeeding women can safely induce functional IgA and IgG responses in serum and breast milk.
Phase 1 study but it will be super dope to protect infants from norovirus by vaccinating mum.
www.nature.com/articles/s41...