Jo Poole

Thanks that’s super helpful!

Anyone know if NHS pensions are tax deductible in terms of adjusted net income?

@mike-ambler.bsky.social

Picture of a naked mole-rat in a fleece bed

🧵1/15 Delighted to share our study on the naked mole-rat (NMR): a mammal with bizarre thermal biology, notorious longevity, and cancer resistance. But how do NMRs maintain (or fail to maintain) their body temperature? Our latest work digs deep! #ThermalBiology #Thermogenesis

Value of cDPP3 as a short-term prognostic biomarker in all-comers critically ill patients in the emergency department - Critical Care

Interesting biomarker for 24 hour and 28 day mortality in critically ill patients (reflects metalloproteinase tissue damage and angiotensin II activity). AUC 0.83 for 24 hour. Interestingly subgroup with elevated biomarker & ACEi use higher mortality ccforum.biomedcentral.com/articles/10.... #emimcc

So very beautiful thank you 🤩 xx

Ha! Yes I’m thrilled eviction happened prior to this heat wave it was unacceptable!

#child#2 is earthside 🥰💕

I think for Colin alone 9/10

Very fair

Influenza Vaccination and Cardiovascular Risk This meta-analysis updates a previous meta-analysis examining the association of seasonal influenza vaccination with prevention of adverse cardiovascular events for a new large clinical trial.

What if something quick and free could cut your heart attack risk by 34%? Getting a flu vaccine each year is linked to a 34% lower risk of major cardiovascular events. jamanetwork.com/journals/jam...

Use of Intralipid in a Propranolol/Quetiapine induced cardiac arrest - our poster today at #SOA25

Evidence for lipid rescue is (and will likely remain) limited, but it really was an inspiring and uplifting case to have been a part of - ROSC after 76 mins CPR and an excellent neurological outcome.

Comes - there are a lot in AKI

I think target trial emulation is an interesting and hypothesis generating method, but I think unless the effect size fairly large, never possible to truly eliminate confounders - I’d also like to see trials start to enrich the likely responders using biomarkers that correlate with functional out

My family had a recent experience of hospital care & we saw effect of this type of taskification of care. Pointless delays, miscommunication, unnecessary referrals etc. No one had the patient at the core of their thinking as they did their bit of the job - result was real anguish

Not all airway compromises would be safe to travel - many of ours done for dental extractions - not sure our network tertiary centre would manage all of those! Huge increased rate since less nhs dentists too

In an ideal world there should be a level 1.5 care for such patients, but when bed bases often limited for level 2 and 3 care, is it justifiable to take patients for enhanced monitoring etc only? It’s not a straight forward situ

These cuts come as high-ranking US officials criticize top journals as ‘woke’ and ‘corrupt’.

In May, RFK Jr threatened to bar government scientists from publishing in top medical journals.

And several journals received letters in April from DOJ alleging political bias in the research they publish.

Just lmao

Once again, this is why we cannot ask pregnant trainees / early career faculty to attend scientific & medical conferences in states that outlaw abortion, and hence why we absolutely must not hold conferences in these states

Mervyn’s suggestions for the next stages of critical care #soa25

Next up: Professor Rockwood (yes, THAT Rockwood) discusses frailty

And here’s his definition

#soa25

Our next session is on the recent excellent @ncepod.bsky.social report on rehabilitation after critical illness

This can be read here ncepod.org.uk/2025icur.html

Spoiler alert: we have much to improve on

#soa25

Honestly could have fed Prof Rockwood Questions for an hour!what a fantastic and relevant session on Frailty #SOA25

At some point we have to decide what we stand for - is human life, let alone innocent child life, worth nothing?

Witnesses describe grim aftermath of Israeli strike on busy Gaza cafe Women, children and elderly people among at least 24 killed by attack that turned beach spot into scene of carnage

These are war crimes, missile attacks in areas full of defenceless civilians and children are pathetic - why is there so much inaction on the atrocities being committed by the IDF? We wouldn’t tolerate other nations doing this? www.theguardian.com/world/2025/j...

the volume of an ellipsoid is ABC/2

so if a patient is in hemorrhagic shock with an 3x4x5 cm hematoma in their abdomen, the hematoma *cannot* explain their hemorrhagic shock (estimated 30 cc volume)

keep looking for the source of bleeding (which statistically is likely to be a GI bleed) #EMIMCC

No we don’t? That’s why it’s being collected? Why’s that a bad thing? I’m just cautious having seen a few is all, I don’t have a problem with their licensed indication but I’m glad we have monitoring schemes to check these events for us

I actually completely disagree with you on both these counts, I don’t think we can safely say there is not an increased risk of pancreatitis, furthermore the mechanism is very clear - they work very particularly on pancreatic hormone and metabolic regulation….

I think the whole point of follow up data is to identify what the rates actually are and potentially identify who is higher risk. Like with the expansion of any medication, one sees more unusual complications the wider the roll out. That’s just good monitoring policy and not isolated to these jabs